Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I
出版年份 2022 全文链接
标题
Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I
作者
关键词
complex I, cryo-electron microscopy, acetogenin, inhibitor-bound structure, binding site
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 298, Issue 3, Pages 101602
出版商
Elsevier BV
发表日期
2022-01-20
DOI
10.1016/j.jbc.2022.101602
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cork-in-bottle mechanism of inhibitor binding to mammalian complex I
- (2021) Injae Chung et al. Science Advances
- Redox- and protonation-state driven substrate-protein dynamics in respiratory complex I
- (2021) Outi Haapanen et al. Current Opinion in Electrochemistry
- Respiratory complex I – Mechanistic insights and advances in structure determination
- (2020) Etienne Galemou Yoga et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I
- (2020) Shinpei Uno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Measurement of atom resolvability in cryo-EM maps with Q-scores
- (2020) Grigore Pintilie et al. NATURE METHODS
- Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in RELION-3.1
- (2020) Jasenko Zivanov et al. IUCrJ
- Coupling of quinone dynamics to proton pumping in respiratory complex I
- (2020) Outi Haapanen et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Respiratory complex I — structure, mechanism and evolution
- (2020) Kristian Parey et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation
- (2020) Daniel N. Grba et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The coupling mechanism of mammalian respiratory complex I
- (2020) Domen Kampjut et al. SCIENCE
- Key role of quinone in the mechanism of respiratory complex I
- (2020) Javier Gutiérrez-Fernández et al. Nature Communications
- Structure of inhibitor-bound mammalian complex I
- (2020) Hannah R. Bridges et al. Nature Communications
- Atomic structure of a mitochondrial complex I intermediate from vascular plants
- (2020) Maria Maldonado et al. eLife
- Balanced internal hydration discriminates substrate binding to respiratory complex I
- (2019) Murilo Hoias Teixeira et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mutations in a conserved loop in the PSST subunit of respiratory complex I affect ubiquinone binding and dynamics
- (2019) Etienne Galemou Yoga et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk
- (2019) James A. Letts et al. MOLECULAR CELL
- Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
- (2019) Dorothee Liebschner et al. Acta Crystallographica Section D-Structural Biology
- Long-range proton-coupled electron transfer in biological energy conversion: towards mechanistic understanding of respiratory complex I
- (2018) Ville R. I. Kaila Journal of the Royal Society Interface
- Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states
- (2018) Ahmed-Noor A. Agip et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- CASTp 3.0: computed atlas of surface topography of proteins
- (2018) Wei Tian et al. NUCLEIC ACIDS RESEARCH
- MonoRes: Automatic and Accurate Estimation of Local Resolution for Electron Microscopy Maps
- (2018) Jose Luis Vilas et al. STRUCTURE
- Analysis of Global and Site-Specific Radiation Damage in Cryo-EM
- (2018) Johan Hattne et al. STRUCTURE
- Structure of the Deactive State of Mammalian Respiratory Complex I
- (2018) James N. Blaza et al. STRUCTURE
- Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states
- (2018) Ahmed-Noor A. Agip et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Redox-coupled quinone dynamics in the respiratory complex I
- (2018) Judith Warnau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- New tools for the analysis and validation of cryo-EM maps and atomic models
- (2018) Pavel V. Afonine et al. Acta Crystallographica Section D-Structural Biology
- Exploring the quinone/inhibitor-binding pocket in mitochondrial respiratory complex I by chemical biology approaches
- (2018) Shinpei Uno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PubChem 2019 update: improved access to chemical data
- (2018) Sunghwan Kim et al. NUCLEIC ACIDS RESEARCH
- New tools for automated high-resolution cryo-EM structure determination in RELION-3
- (2018) Jasenko Zivanov et al. eLife
- Cryo-EM structure of respiratory complex I at work
- (2018) Kristian Parey et al. eLife
- A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis
- (2018) Jasenko Zivanov et al. IUCrJ
- Terminal Electron–Proton Transfer Dynamics in the Quinone Reduction of Respiratory Complex I
- (2017) Ana P. Gamiz-Hernandez et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- Correlating kinetic and structural data on ubiquinone binding and reduction by respiratory complex I
- (2017) Justin G. Fedor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- UCSF ChimeraX: Meeting modern challenges in visualization and analysis
- (2017) Thomas D. Goddard et al. PROTEIN SCIENCE
- Role of water and protein dynamics in proton pumping by respiratory complex I
- (2017) Outi Haapanen et al. Scientific Reports
- Specific Methylation of Asp160 (49 kDa subunit) Located inside the Quinone Binding Cavity of Bovine Mitochondrial Complex I
- (2016) Masatoshi Murai et al. BIOCHEMISTRY
- Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy
- (2016) J.M. de la Rosa-Trevín et al. JOURNAL OF STRUCTURAL BIOLOGY
- Gctf: Real-time CTF determination and correction
- (2016) Kai Zhang JOURNAL OF STRUCTURAL BIOLOGY
- Structure of mammalian respiratory complex I
- (2016) Jiapeng Zhu et al. NATURE
- EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
- (2015) Benjamin A Barad et al. NATURE METHODS
- A giant molecular proton pump: structure and mechanism of respiratory complex I
- (2015) Leonid A. Sazanov NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Redox-induced activation of the proton pump in the respiratory complex I
- (2015) Vivek Sharma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanistic insight from the crystal structure of mitochondrial complex I
- (2015) V. Zickermann et al. SCIENCE
- Site-Specific Chemical Labeling of Mitochondrial Respiratory Complex I through Ligand-Directed Tosylate Chemistry
- (2014) Takahiro Masuya et al. BIOCHEMISTRY
- Pinpoint Chemical Modification of Asp160 in the 49 kDa Subunit of Bovine Mitochondrial Complex I via a Combination of Ligand-Directed Tosyl Chemistry and Click Chemistry
- (2014) Takahiro Masuya et al. BIOCHEMISTRY
- Ultrastable gold substrates for electron cryomicroscopy
- (2014) C. J. Russo et al. SCIENCE
- Mitochondrial Complex I
- (2013) Judy Hirst Annual Review of Biochemistry
- Crystal structure of the entire respiratory complex I
- (2013) Rozbeh Baradaran et al. NATURE
- Tracing the tail of ubiquinone in mitochondrial complex I
- (2012) Heike Angerer et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Bis-THF motif of acetogenin binds to the third matrix-side loop of ND1 subunit in mitochondrial NADH-ubiquinone oxidoreductase
- (2011) Sayo Nakanishi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- A two-state stabilization-change mechanism for proton-pumping complex I
- (2011) Ulrich Brandt BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Exploring the Binding Site of Δlac-Acetogenin in Bovine Heart Mitochondrial NADH−Ubiquinone Oxidoreductase
- (2010) Nobuyuki Kakutani et al. BIOCHEMISTRY
- Quinone binding and reduction by respiratory complex I
- (2010) Maja A. Tocilescu et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- electronic Ligand Builder and Optimization Workbench(eLBOW): a tool for ligand coordinate and restraint generation
- (2009) Nigel W. Moriarty et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Exploring the binding site of acetogenin in the ND1 subunit of bovine mitochondrial complex I
- (2009) Koji Sekiguchi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Isolation of mitochondria for biogenetical studies: An update
- (2009) Erika Fernández-Vizarra et al. MITOCHONDRION
- Dynamic Function of the Spacer Region of Acetogenins in the Inhibition of Bovine Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I)†
- (2008) Masato Abe et al. BIOCHEMISTRY
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