Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states

Global collective motions in the mammalian and bacterial respiratory complex I

(2018) Andrea Di Luca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Structure of the Deactive State of Mammalian Respiratory Complex I

(2018) James N. Blaza et al.   STRUCTURE

Using Hyperfine Electron Paramagnetic Resonance Spectroscopy to Define the Proton-Coupled Electron Transfer Reaction at Fe–S Cluster N2 in Respiratory Complex I

(2017) Nolwenn Le Breton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Terminal Electron–Proton Transfer Dynamics in the Quinone Reduction of Respiratory Complex I

(2017) Ana P. Gamiz-Hernandez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Accurate model annotation of a near-atomic resolution cryo-EM map

(2017) Corey F. Hryc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Correlating kinetic and structural data on ubiquinone binding and reduction by respiratory complex I

(2017) Justin G. Fedor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Symmetry-related proton transfer pathways in respiratory complex I

(2017) Andrea Di Luca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: More and better reference data for improved all-atom structure validation

(2017) Christopher J. Williams et al.   PROTEIN SCIENCE

Modulation of the conformational state of mitochondrial complex I as a target for therapeutic intervention

(2017) Alexander Galkin et al.   Interface Focus

A pipeline approach to single-particle processing inRELION

(2017) Rafael Fernandez-Leiro et al.   Acta Crystallographica Section D-Structural Biology

Role of water and protein dynamics in proton pumping by respiratory complex I

(2017) Outi Haapanen et al.   Scientific Reports

The origin of the supernumerary subunits and assembly factors of complex I: A treasure trove of pathway evolution

(2016) Dei M. Elurbe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Energy conversion, redox catalysis and generation of reactive oxygen species by respiratory complex I

(2016) Judy Hirst et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Structure of Mammalian Respiratory Supercomplex I 1 III 2 IV 1

(2016) Meng Wu et al.   CELL

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

The architecture of respiratory supercomplexes

(2016) James A. Letts et al.   NATURE

Structure of mammalian respiratory complex I

(2016) Jiapeng Zhu et al.   NATURE

Atomic structure of the entire mammalian mitochondrial complex I

(2016) Karol Fiedorczuk et al.   NATURE

Accessory subunits are integral for assembly and function of human mitochondrial complex I

(2016) David A. Stroud et al.   NATURE

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

Dissecting π-helices: sequence, structure and function

(2015) Prasun Kumar et al.   FEBS Journal

Constraining the Lateral Helix of Respiratory Complex I by Cross-linking Does Not Impair Enzyme Activity or Proton Translocation

(2015) Shaotong Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy

(2015) Benjamin A Barad et al.   NATURE METHODS

Structure of subcomplex Iβ of mammalian respiratory complex I leads to new supernumerary subunit assignments

(2015) Jiapeng Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox-induced activation of the proton pump in the respiratory complex I

(2015) Vivek Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic insight from the crystal structure of mitochondrial complex I

(2015) V. Zickermann et al.   SCIENCE

Characterisation of the active/de-active transition of mitochondrial complex I

(2014) Marion Babot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Architecture of mammalian respiratory complex I

(2014) Kutti R. Vinothkumar et al.   NATURE

A series of PDB-related databanks for everyday needs

(2014) Wouter G. Touw et al.   NUCLEIC ACIDS RESEARCH

Electrostatics, hydration, and proton transfer dynamics in the membrane domain of respiratory complex I

(2014) V. R. I. Kaila et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrastable gold substrates for electron cryomicroscopy

(2014) C. J. Russo et al.   SCIENCE

Mitochondrial Complex I

(2013) Judy Hirst   Annual Review of Biochemistry

Post-translational Modifications near the Quinone Binding Site of Mammalian Complex I

(2013) Joe Carroll et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the entire respiratory complex I

(2013) Rozbeh Baradaran et al.   NATURE

Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I

(2013) Edward T Chouchani et al.   NATURE MEDICINE

Asp563 of the horizontal helix of subunit NuoL is involved in proton translocation by the respiratory complex I

(2012) Stefan Steimle et al.   FEBS LETTERS

Complex I deficiency: clinical features, biochemistry and molecular genetics

(2012) Elisa Fassone et al.   JOURNAL OF MEDICAL GENETICS

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures

(2012) Eva Chovancova et al.   PLoS Computational Biology

Mitochondrial complex III stabilizes complex I in the absence of NDUFS4 to provide partial activity

(2011) M. A. Calvaruso et al.   HUMAN MOLECULAR GENETICS

Probing the mechanistic role of the long α-helix in subunit L of respiratory Complex I from Escherichia coli by site-directed mutagenesis

(2011) Galina Belevich et al.   MOLECULAR MICROBIOLOGY

Structure of the membrane domain of respiratory complex I

(2011) Rouslan G. Efremov et al.   NATURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Truncation of subunit ND2 disrupts the threefold symmetry of the antiporter-like subunits in complex I from higher metazoans

(2010) James A. Birrell et al.   FEBS LETTERS

Evolutionary Origin of a Secondary Structure: π-Helices as Cryptic but Widespread Insertional Variations of α-Helices That Enhance Protein Functionality

(2010) Richard B. Cooley et al.   JOURNAL OF MOLECULAR BIOLOGY

Lack of Oxygen Deactivates Mitochondrial Complex I

(2009) Alexander Galkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation of mitochondria for biogenetical studies: An update

(2009) Erika Fernández-Vizarra et al.   MITOCHONDRION

Structural Basis for Substrate Promiscuity of dCK

(2008) Elisabetta Sabini et al.   JOURNAL OF MOLECULAR BIOLOGY