Overexpression of pyruvate kinase M2 associates with aggressive clinicopathological features and unfavorable prognosis in oral squamous cell carcinoma

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer

(2015) Zhongwu li et al.   Oncotarget

Overexpression of metabolic markers PKM2 and LDH5 correlates with aggressive clinicopathological features and adverse patient prognosis in tongue cancer

(2014) Chunping Yuan et al.   HISTOPATHOLOGY

Oncogenic roles of Bmi1 and its therapeutic inhibition by histone deacetylase inhibitor in tongue cancer

(2014) Zhongwu Li et al.   LABORATORY INVESTIGATION

Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition

(2014) A. Hamabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Value of Expression of M2-PK and VEGF in Patients with Advanced Gastric Cancer

(2013) Lanning Yin et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Aberrant Overexpression of Pyruvate Kinase M2 Is Associated With Aggressive Tumor Features and theBRAFMutation in Papillary Thyroid Cancer

(2013) Chen Feng et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pharmacologic Activation of PKM2 Slows Lung Tumor Xenograft Growth

(2013) K. M. Parnell et al.   MOLECULAR CANCER THERAPEUTICS

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1 -mediated glucose metabolism

(2013) H.-J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Pyruvate Kinase M2: Multiple Faces for Conferring Benefits on Cancer Cells

(2012) M. Tamada et al.   CLINICAL CANCER RESEARCH

Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression

(2012) Michael S. Goldberg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Development of a 4-nitroquinoline-1-oxide model of lymph node metastasis in oral squamous cell carcinoma

(2012) Jing Li et al.   ORAL ONCOLOGY

Gene Expression Signature of DMBA-Induced Hamster Buccal Pouch Carcinomas: Modulation by Chlorophyllin and Ellagic Acid

(2012) Ramamurthi Vidya Priyadarsini et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Aberrant expression in multiple components of the transforming growth factor-β1-induced Smad signaling pathway during 7,12-dimethylbenz[a]anthracene-induced hamster buccal-pouch squamous-cell carcinogenesis

(2011) Yuk-Kwan Chen et al.   ORAL ONCOLOGY

Comparative Proteomic Approach Identifies Pkm2 and Cofilin-1 as Potential Diagnostic, Prognostic and Therapeutic Targets for Pulmonary Adenocarcinoma

(2011) Xing-chen Peng et al.   PLoS One

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Prognostic evaluation of oral tongue cancer: Means, markers and perspectives (II)

(2010) Ibrahim O. Bello et al.   ORAL ONCOLOGY

Major advances in the knowledge and understanding of the epidemiology, aetiopathogenesis, diagnosis, management and prognosis of oral cancer

(2009) Alexander D. Rapidis et al.   ORAL ONCOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Identification of pyruvate kinase type M2 as potential oncoprotein in squamous cell carcinoma of tongue through microRNA profiling

(2008) Thian-Sze Wong et al.   INTERNATIONAL JOURNAL OF CANCER