Curcumin mitigates aflatoxin B1-induced liver injury via regulating the NLRP3 inflammasome and Nrf2 signaling pathway

Dietary Resveratrol Alleviates AFB1-Induced Ileum Damage in Ducks via the Nrf2 and NF-κB/NLRP3 Signaling Pathways and CYP1A1/2 Expressions

(2022) Hao Yang et al.   Agriculture-Basel

Contamination of Aflatoxins Induces Severe Hepatotoxicity Through Multiple Mechanisms

(2021) Zhenglai Hua et al.   Frontiers in Pharmacology

Bacillus amyloliquefaciens B10 can alleviate liver apoptosis and oxidative stress induced by aflatoxin B1

(2021) Xiaotong Li et al.   FOOD AND CHEMICAL TOXICOLOGY

Ligustrazine alleviates cyclophosphamide-induced hepatotoxicity via the inhibition of Txnip/Trx/NF-κB pathway

(2021) Xinfei Ma et al.   LIFE SCIENCES

Research Progress on the Protection and Detoxification of Phytochemicals against Aflatoxin B1-Induced Liver Toxicity

(2021) Tingting Fan et al.   TOXICON

Effects of dietary resveratrol supplementation on the chemical composition, oxidative stability and meat quality of ducks (Anas platyrhynchos)

(2021) Sanjun Jin et al.   FOOD CHEMISTRY

Formononetin ameliorates myocardial ischemia/reperfusion injury in rats by suppressing the ROS-TXNIP-NLRP3 pathway

(2020) Dan-Shu Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PTUPB ameliorates high-fat diet-induced non-alcoholic fatty liver disease via inhibiting NLRP3 inflammasome activation in mice

(2020) Chen-Chen Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

(2020) Mausita Karmakar et al.   Nature Communications

Aflatoxin B1-Induced COX-2 Expression Promotes Mitophagy and Contributes to Lipid Accumulation in Hepatocytes In Vitro and In Vivo

(2020) Xin-Lu Ren et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis

(2020) Susanne Gaul et al.   JOURNAL OF HEPATOLOGY

Protective Effect of Low Molecular Weight Peptides from Solenocera crassicornis Head against Cyclophosphamide-Induced Nephrotoxicity in Mice via the Keap1/Nrf2 Pathway

(2020) Shuoqi Jiang et al.   Antioxidants

COVID‐19: A Case for Inhibiting NLRP3 Inflammasome, Suppression of Inflammation with Curcumin?

(2020) Ali Saeedi‐Boroujeni et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Melatonin attenuates AFB1-induced cardiotoxicity via the NLRP3 signalling pathway

(2020) Hui Yan et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Avian host defense cathelicidins: structure, expression, biological functions, and potential therapeutic applications

(2020) Yingjie Wang et al.   POULTRY SCIENCE

Counteracting arsenic toxicity: Curcumin to the rescue?

(2020) Afsane Bahrami et al.   JOURNAL OF HAZARDOUS MATERIALS

Detection of Aflatoxin adducts as potential markers and the role of curcumin in alleviating AFB1-induced liver damage in chickens

(2019) Sihong Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Aflatoxin B1 enhances pyroptosis of hepatocytes and activation of Kupffer cells to promote liver inflammatory injury via dephosphorylation of cyclooxygenase-2: an in vitro, ex vivo and in vivo study

(2019) Li-Yin Zhang et al.   ARCHIVES OF TOXICOLOGY

6-Gingerol attenuates macrophages pyroptosis via the inhibition of MAPK signaling pathways and predicts a good prognosis in sepsis

(2019) Fang-Ling Zhang et al.   CYTOKINE

Mitochondrial damage are involved in Aflatoxin B1-induced testicular damage and spermatogenesis disorder in mice

(2019) Wanyue Huang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-κB signaling

(2019) Xueliang Chen et al.   Cell Death & Disease

Effect of some safe feed additives on growth performance, blood biochemistry, and bioaccumulation of aflatoxin residues of Nile tilapia fed aflatoxin-B 1 contaminated diet

(2018) Mohamed Salah Ayyat et al.   AQUACULTURE

Sensitivity of Arbor Acres broilers and chemoprevention of aflatoxin B 1 -induced liver injury by curcumin, a natural potent inducer of phase-II enzymes and Nrf2

(2018) He Wang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Curcumin Attenuates on Carbon Tetrachloride-Induced Acute Liver Injury in Mice via Modulation of the Nrf2/HO-1 and TGF-β1/Smad3 Pathway

(2018) Xinyan Peng et al.   MOLECULES

Biochemical basis for the age-related sensitivity of broilers to aflatoxin B1

(2018) He Wang et al.   TOXICOLOGY MECHANISMS AND METHODS

Biochemical basis for the age-related sensitivity of broilers to aflatoxin B1

(2018) He Wang et al.   TOXICOLOGY MECHANISMS AND METHODS

Dual Role of Dietary Curcumin Through Attenuating AFB1-Induced Oxidative Stress and Liver Injury via Modulating Liver Phase-I and Phase-II Enzymes Involved in AFB1 Bioactivation and Detoxification

(2018) Ishfaq Muhammad et al.   Frontiers in Pharmacology

Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods

(2018) Blake R. Rushing et al.   FOOD AND CHEMICAL TOXICOLOGY

Identification of essential transcription factors for adequate DNA damage response after benzo(a)pyrene and aflatoxin B1 exposure by combining transcriptomics with functional genomics

(2017) Evelyn Smit et al.   TOXICOLOGY

Lycopene relieves AFB 1 -induced liver injury through enhancing hepatic antioxidation and detoxification potential with Nrf2 activation

(2017) Feibo Xu et al.   Journal of Functional Foods

Turmeric extract and its active compound, curcumin, protect against chronic CCl4-induced liver damage by enhancing antioxidation

(2016) Hwa-Young Lee et al.   BMC Complementary and Alternative Medicine

Is Liver Enzyme Release Really Associated with Cell Necrosis Induced by Oxidant Stress?

(2016) Martha Lucinda Contreras-Zentella et al.   Oxidative Medicine and Cellular Longevity

Curcumin Prevents Aflatoxin B1 Hepatoxicity by Inhibition of Cytochrome P450 Isozymes in Chick Liver

(2016) Ni-Ya Zhang et al.   Toxins

Detoxification and antioxidant effects of garlic and curcumin in Oreochromis niloticus injected with aflatoxin B1 with reference to gene expression of glutathione peroxidase (GPx) by RT-PCR

(2015) Manal I. El-Barbary   FISH PHYSIOLOGY AND BIOCHEMISTRY

Ameliorative effect of curcumin on aflatoxin B1-induced changes in liver gene expression of Oreochromis niloticus

(2015) M. E. Mahfouz   MOLECULAR BIOLOGY

Curcumin suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

(2015) Zizhen Gong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Selection, identification, and application of Aflatoxin B1 aptamer

(2014) Xiaoyuan Ma et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Effect of Curcumin on Hepatic Antioxidant Enzymes Activities and Gene Expressions in Rats Intoxicated with Aflatoxin B1

(2014) S. M. El-Bahr   PHYTOTHERAPY RESEARCH

Overview on aflatoxins and oxidative stress

(2013) Daniela E. Marin et al.   Toxin Reviews

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

(2012) Holly K. Bryan et al.   BIOCHEMICAL PHARMACOLOGY

Curcumin alleviates oxidative stress, inflammation, and renal fibrosis in remnant kidney through the Nrf2-keap1 pathway

(2012) Vivian Soetikno et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammasome activation and IL-1β and IL-18 processing during infection

(2011) Frank L. van de Veerdonk et al.   TRENDS IN IMMUNOLOGY

Comparative effects of curcumin and resveratrol on aflatoxin B1-induced liver injury in rats

(2010) Dina S. El-Agamy   ARCHIVES OF TOXICOLOGY

Expression, Function and Regulation of Mouse Cytochrome P450 Enzymes: Comparison With Human Cytochrome P450 Enzymes

(2010) E. Hrycay et al.   CURRENT DRUG METABOLISM

Inhibitory effects of quercetin on aflatoxin B1-induced hepatic damage in mice

(2010) K.-C. Choi et al.   FOOD AND CHEMICAL TOXICOLOGY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[ a ]pyrene-treated mice: mechanism of its anti-initiating action

(2008) Rachana Garg et al.   CARCINOGENESIS

Naturally occurring chlorophyll derivatives inhibit aflatoxin B1-DNA adduct formation in hepatoma cells

(2008) Ching-Yun Hsu et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1

(2007) E. Olatunde Farombi et al.   FOOD AND CHEMICAL TOXICOLOGY