Glycosylation as a key parameter in the design of nucleic acid vaccines

A cross-neutralizing antibody between HIV-1 and influenza virus

(2021) Chang-Chun D. Lee et al.   PLoS Pathogens

Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged ≥65 Years — United States, January–March 2021

(2021) Mark W. Tenforde et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Recent developments and strategies of Ebola virus vaccines

(2021) Ashish Ranjan Sharma et al.   CURRENT OPINION IN PHARMACOLOGY

Immune Responses to Viral Gene Therapy Vectors

(2020) Jamie L. Shirley et al.   MOLECULAR THERAPY

Host protein glycosylation in nucleic acid vaccines as a potential hurdle in vaccine design for nonviral pathogens

(2020) Ahmet Ozdilek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

(2020) Dora Pinto et al.   NATURE

Site-specific glycan analysis of the SARS-CoV-2 spike

(2020) Yasunori Watanabe et al.   SCIENCE

Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help

(2020) Lina Sun et al.   Nature Communications

Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy

(2020) Florent Colomb et al.   Cell Reports

Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor

(2020) Peng Zhao et al.   Cell Host & Microbe

Self-amplifying RNA vaccines for infectious diseases

(2020) Kristie Bloom et al.   GENE THERAPY

Visualization of the HIV-1 Env glycan shield across scales

(2020) Zachary T. Berndsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-α alters host glycosylation machinery during treated HIV infection

(2020) Leila B. Giron et al.   EBioMedicine

The Science is There: Key Considerations for Stabilizing Viral Vector-Based Covid-19 Vaccines

(2020) Daan J.A. Crommelin et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Exploitation of glycosylation in enveloped virus pathobiology

(2019) Yasunori Watanabe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development

(2019) Fikri Avci et al.   mSphere

Structure and Immune Recognition of the HIV Glycan Shield

(2018) Max Crispin et al.   Annual Review of Biophysics

Universal Vaccines and Vaccine Platforms to Protect against Influenza Viruses in Humans and Agriculture

(2018) Daniela S. Rajão et al.   Frontiers in Microbiology

Engineering DNA vaccines against infectious diseases

(2018) Jihui Lee et al.   Acta Biomaterialia

Metabolic labeling of HIV-1 envelope glycoprotein gp120 to elucidate the effect of gp120 glycosylation on antigen uptake

(2018) Lina Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycans as Key Checkpoints of T Cell Activity and Function

(2018) Márcia S. Pereira et al.   Frontiers in Immunology

Glycan–protein interactions in viral pathogenesis

(2016) Rahul Raman et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Carbohydrates as T-cell antigens with implications in health and disease

(2016) Lina Sun et al.   GLYCOBIOLOGY

Biological roles of glycans

(2016) Ajit Varki   GLYCOBIOLOGY

Thetrans-sialidase, the majorTrypanosoma cruzivirulence factor: Three decades of studies

(2015) L Freire-de-Lima et al.   GLYCOBIOLOGY

A double-blind, randomised, placebo-controlled, dose-finding trial of the novel tuberculosis vaccine AERAS-402, an adenovirus-vectored fusion protein, in healthy, BCG-vaccinated infants

(2015) M. Tameris et al.   VACCINE

Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial

(2015) Birahim Pierre Ndiaye et al.   Lancet Respiratory Medicine

Vaccines for the 21st century

(2014) I. Delany et al.   EMBO Molecular Medicine

The interplay between Siglecs and sialylated pathogens

(2014) Y.-C. Chang et al.   GLYCOBIOLOGY

Novel Strategies for Development of Next-Generation Glycoconjugate Vaccines

(2013) Fikri Avci   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Glycosylation of Serum Proteins in Inflammatory Diseases

(2013) Olga Gornik et al.   DISEASE MARKERS

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

(2013) Michele D Tameris et al.   LANCET

Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion

(2013) Jason E Hudak et al.   Nature Chemical Biology

O-mannosylation of the Mycobacterium tuberculosis Adhesin Apa Is Crucial for T Cell Antigenicity during Infection but Is Expendable for Protection

(2013) Subhadra Nandakumar et al.   PLoS Pathogens

Siglecs as sensors of self in innate and adaptive immune responses

(2012) James C. Paulson et al.   Annals of the New York Academy of Sciences

Sialoglycoproteins adsorbed by Pseudomonas aeruginosa facilitate their survival by impeding neutrophil extracellular trap through siglec-9

(2012) B. Khatua et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Campylobacter Polysaccharide Capsules: Virulence and Vaccines

(2012) Patricia Guerry et al.   Frontiers in Cellular and Infection Microbiology

Letter to the Glyco-Forum: Since there are PAMPs and DAMPs, there must be SAMPs? Glycan "self-associated molecular patterns" dampen innate immunity, but pathogens can mimic them

(2011) A. Varki   GLYCOBIOLOGY

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

(2011) Jason S. McLellan et al.   NATURE

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

(2011) R. Pejchal et al.   SCIENCE

Capsules ofStreptococcus pneumoniaeand Other Bacteria: Paradigms for Polysaccharide Biosynthesis and Regulation

(2010) Janet Yother   Annual Review of Microbiology

Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response

(2009) A. F. Carlin et al.   BLOOD

Viruses as vaccine vectors for infectious diseases and cancer

(2009) Simon J. Draper et al.   NATURE REVIEWS MICROBIOLOGY