The Science is There: Key Considerations for Stabilizing Viral Vector-Based Covid-19 Vaccines

Evaluation of the stability of measles vaccine out of the cold chain under extended controlled temperature conditions

(2020) Aitana Juan-Giner et al.   VACCINE

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

(2020) Feng-Cai Zhu et al.   LANCET

Simian adenovirus vector production for early-phase clinical trials: A simple method applicable to multiple serotypes and using entirely disposable product-contact components

(2019) Sofiya Fedosyuk et al.   VACCINE

Algorithm-based liquid formulation development including a DoE concept predicts long-term viral vector stability

(2019) E.B. Reinauer et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Physical characterization and stabilization of a lentiviral vector against adsorption and freeze-thaw

(2018) Ozan S. Kumru et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Combined semi-empirical screening and design of experiments (DOE) approach to identify candidate formulations of a lyophilized live attenuated tetravalent viral vaccine candidate

(2018) Ashaben Patel et al.   VACCINE

Evaluation of the thermal stability of live-attenuated Rubella vaccine (Takahashi strain) formulated and lyophilized in different stabilizers

(2018) Somayeh Shokri et al.   JOURNAL OF VIROLOGICAL METHODS

Stability of heat stable, live attenuated Rotavirus vaccine (ROTASIIL®)

(2017) Sameer P. Naik et al.   VACCINE

Stabilization of Live Attenuated Influenza Vaccines by Freeze Drying, Spray Drying, and Foam Drying

(2016) Phillip M. Lovalenti et al.   PHARMACEUTICAL RESEARCH

Live attenuated and inactivated viral vaccine formulation and nasal delivery: Potential and challenges

(2015) José L. Tlaxca et al.   ADVANCED DRUG DELIVERY REVIEWS

Freeze-drying of live virus vaccines: A review

(2015) L.J.J. Hansen et al.   VACCINE

Vaccine instability in the cold chain: Mechanisms, analysis and formulation strategies

(2014) Ozan S. Kumru et al.   BIOLOGICALS

Towards ambient temperature-stable vaccines: The identification of thermally stabilizing liquid formulations for measles virus using an innovative high-throughput infectivity assay

(2011) Lisa D. Schlehuber et al.   VACCINE

Development of a stabilizer for lyophilization of an attenuated duck viral hepatitis vaccine

(2010) M. S. Kang et al.   POULTRY SCIENCE