Lepr+ mesenchymal cells sense diet to modulate intestinal stem/progenitor cells via Leptin–Igf1 axis

MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche

(2021) Ningbo Wu et al.   NATURE

Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient

(2020) Neil McCarthy et al.   Cell Stem Cell

Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium

(2020) Thierry Jardé et al.   Cell Stem Cell

Cycling Stem Cells Are Radioresistant and Regenerate the Intestine

(2020) Xiaole Sheng et al.   Cell Reports

Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury

(2020) Natacha Bohin et al.   Cellular and Molecular Gastroenterology and Hepatology

Mapping Development of the Human Intestinal Niche at Single-Cell Resolution

(2020) Emily M. Holloway et al.   Cell Stem Cell

Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

(2019) Christian F. Guerrero-Juarez et al.   Nature Communications

Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data

(2019) Samuel L. Wolock et al.   Cell Systems

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses

(2019) Neil Murphy et al.   GASTROENTEROLOGY

Dietary Factors in the Control of Gut Homeostasis, Intestinal Stem Cells, and Colorectal Cancer

(2019) Federica Francescangeli et al.   Nutrients

Nutritional Regulation of Intestinal Stem Cells

(2018) Salvador Alonso et al.   Annual Review of Nutrition

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

(2018) Maria M. Mihaylova et al.   Cell Stem Cell

Insulin/IGF-1 enhances intestinal epithelial crypt proliferation through PI3K/Akt, and not ERK signaling in obese humans

(2018) Weinan Zhou et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Chemerin: a multifaceted adipokine involved in metabolic disorders

(2018) Gisela Helfer et al.   JOURNAL OF ENDOCRINOLOGY

PDGFRα+pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo

(2018) Gediminas Greicius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting the Role of Eotaxin-1/CCL11 in Psychiatric Disorders

(2018) Antonio L. Teixeira et al.   Frontiers in Psychiatry

Subepithelial telocytes are an important source of Wnts that supports intestinal crypts

(2018) Michal Shoshkes-Carmel et al.   NATURE

GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells

(2018) Bahar Degirmenci et al.   NATURE

Differential cytokine contributions of perivascular haematopoietic stem cell niches

(2017) Noboru Asada et al.   NATURE CELL BIOLOGY

CD34+mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury

(2017) Igor Stzepourginski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

(2016) Semir Beyaz et al.   NATURE

IGF1 stimulates crypt expansion via differential activation of 2 intestinal stem cell populations

(2015) Laurianne Van Landeghem et al.   FASEB JOURNAL

Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism

(2015) Hyeong-Kyu Park et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Overview of Complement Activation and Regulation

(2013) Marina Noris et al.   SEMINARS IN NEPHROLOGY

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

OLFM4 Is a Robust Marker for Stem Cells in Human Intestine and Marks a Subset of Colorectal Cancer Cells

(2009) Laurens G. van der Flier et al.   GASTROENTEROLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE