Insulin/IGF-1 enhances intestinal epithelial crypt proliferation through PI3K/Akt, and not ERK signaling in obese humans
出版年份 2018 全文链接
标题
Insulin/IGF-1 enhances intestinal epithelial crypt proliferation through PI3K/Akt, and not ERK signaling in obese humans
作者
关键词
-
出版物
EXPERIMENTAL BIOLOGY AND MEDICINE
Volume -, Issue -, Pages 153537021878515
出版商
SAGE Publications
发表日期
2018-06-28
DOI
10.1177/1535370218785152
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Insulin induction instigates cell proliferation and metastasis in human colorectal cancer cells
- (2017) Chi-Cheng Lu et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Intestinal stem cells contribute to the maturation of the neonatal small intestine and colon independently of digestive activity
- (2017) Hirotsugu Yanai et al. Scientific Reports
- High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
- (2016) Semir Beyaz et al. NATURE
- Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition
- (2016) Valentine Comaills et al. Cell Reports
- IGF1 stimulates crypt expansion via differential activation of 2 intestinal stem cell populations
- (2015) Laurianne Van Landeghem et al. FASEB JOURNAL
- Variation in cancer risk among tissues can be explained by the number of stem cell divisions
- (2015) C. Tomasetti et al. SCIENCE
- Effects of insulin on human pancreatic cancer progression modeled in vitro
- (2014) Michelle T Chan et al. BMC CANCER
- Impact of Diet-Induced Obesity on Intestinal Stem Cells: Hyperproliferation but Impaired Intrinsic Function That Requires Insulin/IGF1
- (2014) Amanda T. Mah et al. ENDOCRINOLOGY
- Nutrient-induced intestinal adaption and its effect in obesity
- (2014) Megan J. Dailey PHYSIOLOGY & BEHAVIOR
- Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain
- (2014) Karyn J. Catalano et al. PLoS One
- Insulin Receptor Signaling in Normal and Insulin-Resistant States
- (2014) J. Boucher et al. Cold Spring Harbor Perspectives in Biology
- Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon
- (2014) Ann-Marie Baker et al. Cell Reports
- Obesity and colorectal cancer
- (2013) Marc Bardou et al. GUT
- Role of insulin resistance in endothelial dysfunction
- (2013) Ranganath Muniyappa et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance
- (2012) Edita Aksamitiene et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Small Intestinal Alterations in Severely Obese Hyperglycemic Subjects
- (2010) Froukje J. Verdam et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Crypt stem cells as the cells-of-origin of intestinal cancer
- (2008) Nick Barker et al. NATURE
- Similarities and differences between insulin and IGF-I: Structures, receptors, and signalling pathways
- (2008) Haim Werner et al. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started