Directing Multivalent Aptamer‐Receptor Binding on the Cell Surface with Programmable Atom‐Like Nanoparticles

T cell circuits that sense antigen density with an ultrasensitive threshold

(2021) Rogelio A. Hernandez-Lopez et al.   SCIENCE

Enhancing anti‐PD‐1 immunotherapy by nanomicelles self‐assembled from aptamer‐multivalent‐drug conjugates

(2021) Zhongmin Geng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Encoding Fluorescence Anisotropic Barcodes with DNA Frameworks

(2021) Qiuling Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers

(2021) Edurne Rujas et al.   Nature Communications

Encoding quantized fluorescence states with fractal DNA frameworks

(2020) Jiang Li et al.   Nature Communications

Programming Biomimetically Confined Aptamers with DNA Frameworks

(2020) Xiuhai Mao et al.   ACS Nano

Barcoded DNA origami structures for multiplexed optimization and enrichment of DNA-based protein-binding cavities

(2020) Ali Aghebat Rafat et al.   Nature Chemistry

Role of nanoscale antigen organization on B-cell activation probed using DNA origami

(2020) Rémi Veneziano et al.   Nature Nanotechnology

DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation

(2020) Xiao Huang et al.   Nature Nanotechnology

Differential organization of tonic and chronic B cell antigen receptors in the plasma membrane

(2019) Maria Angela Gomes de Castro et al.   Nature Communications

DNA Framework-Programmed Cell Capture via Topology-Engineered Receptor–Ligand Interactions

(2019) Min Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

EpCAM Aptamer-Functionalized Cationic Liposome-Based Nanoparticles Loaded with miR-139-5p for Targeted Therapy in Colorectal Cancer

(2019) Yuyu Zhao et al.   MOLECULAR PHARMACEUTICS

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

(2019) Paul S. Kwon et al.   Nature Chemistry

Quantitatively Mapping the Assembly Pattern of EpCAM on Cell Membranes with Peptide Probes

(2019) Yingying Jing et al.   ANALYTICAL CHEMISTRY

Programming nanoparticle valence bonds with single-stranded DNA encoders

(2019) Guangbao Yao et al.   NATURE MATERIALS

DNA-Assembled Advanced Plasmonic Architectures

(2018) Na Liu et al.   CHEMICAL REVIEWS

Concept and Development of Framework Nucleic Acids

(2018) Zhilei Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simultaneous targeting of CD44 and EpCAM with a bispecific aptamer effectively inhibits intraperitoneal ovarian cancer growth

(2017) Jingying Zheng et al.   Theranostics

DNA nanotechnology

(2017) Nadrian C. Seeman et al.   Nature Reviews Materials

Analysis of aptamer discovery and technology

(2017) Matthew R. Dunn et al.   Nature Reviews Chemistry

EpCAM aptamer-functionalized mesoporous silica nanoparticles for efficient colon cancer cell-targeted drug delivery

(2016) Xiaodong Xie et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Self-Assembly of Molecule-like Nanoparticle Clusters Directed by DNA Nanocages

(2015) Yulin Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Programmable materials and the nature of the DNA bond

(2015) M. R. Jones et al.   SCIENCE

Spatial control of membrane receptor function using ligand nanocalipers

(2014) Alan Shaw et al.   NATURE METHODS

Selection of DNA Aptamers against Epithelial Cell Adhesion Molecule for Cancer Cell Imaging and Circulating Tumor Cell Capture

(2013) Yanling Song et al.   ANALYTICAL CHEMISTRY

Nucleic Acid-Modified Nanostructures as Programmable Atom Equivalents: Forging a New “Table of Elements”

(2013) Robert J. Macfarlane et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Noncanonical Self-Assembly of Multifunctional DNA Nanoflowers for Biomedical Applications

(2013) Guizhi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multivalency as a Chemical Organization and Action Principle

(2012) Carlo Fasting et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA Origami as a Carrier for Circumvention of Drug Resistance

(2012) Qiao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies

(2010) Markus Münz et al.   Cancer Cell International

DNA-nanoparticle superlattices formed from anisotropic building blocks

(2010) Matthew R. Jones et al.   NATURE MATERIALS

The Emerging Role of EpCAM in Cancer and Stem Cell Signaling

(2009) M. Munz et al.   CANCER RESEARCH

Nuclear signalling by tumour-associated antigen EpCAM

(2009) Dorothea Maetzel et al.   NATURE CELL BIOLOGY

The human IgM pentamer is a mushroom-shaped molecule with a flexural bias

(2009) D. M. Czajkowsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-assembled DNA nanostructures for distance-dependent multivalent ligand–protein binding

(2008) Sherri Rinker et al.   Nature Nanotechnology