标题
Analysis of aptamer discovery and technology
作者
关键词
-
出版物
Nature Reviews Chemistry
Volume 1, Issue 10, Pages 0076
出版商
Springer Nature
发表日期
2017-10-04
DOI
10.1038/s41570-017-0076
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Selection of 2′-Fluoro-Modified Aptamers with Optimized Properties
- (2017) Deepak Thirunavukarasu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The chemical evolution of oligonucleotide therapies of clinical utility
- (2017) Anastasia Khvorova et al. NATURE BIOTECHNOLOGY
- Synthesis and polymerase activity of a fluorescent cytidine TNA triphosphate analogue
- (2017) Hui Mei et al. NUCLEIC ACIDS RESEARCH
- A thermostable d-polymerase for mirror-image PCR
- (2017) Andreas Pech et al. NUCLEIC ACIDS RESEARCH
- Selection of DNA aptamers with two modified bases
- (2017) Bharat N. Gawande et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enzymatic Synthesis of Sequence-Defined Synthetic Nucleic Acid Polymers with Diverse Functional Groups
- (2016) Dehui Kong et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Multiparameter Particle Display (MPPD): A Quantitative Screening Method for the Discovery of Highly Specific Aptamers
- (2016) Jinpeng Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Selection platforms for directed evolution in synthetic biology
- (2016) P. A. G. Tizei et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Evaluating TNA stability under simulated physiological conditions
- (2016) Michelle C. Culbertson et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Destabilization of B2 RNA by EZH2 Activates the Stress Response
- (2016) Athanasios Zovoilis et al. CELL
- Reverse Transcription of Threose Nucleic Acid by a Naturally Occurring DNA Polymerase
- (2016) Matthew R. Dunn et al. CHEMBIOCHEM
- Embracing proteins: structural themes in aptamer–protein complexes
- (2016) Amy D Gelinas et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- High-Affinity DNA Aptamer Generation Targeting von Willebrand Factor A1-Domain by Genetic Alphabet Expansion for Systematic Evolution of Ligands by Exponential Enrichment Using Two Types of Libraries Composed of Five Different Bases
- (2016) Ken-ichiro Matsunaga et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor
- (2016) Alem W Kahsai et al. Nature Chemical Biology
- A synthetic molecular system capable of mirror-image genetic replication and transcription
- (2016) Zimou Wang et al. Nature Chemistry
- Aptamers as targeted therapeutics: current potential and challenges
- (2016) Jiehua Zhou et al. NATURE REVIEWS DRUG DISCOVERY
- Evoking picomolar binding in RNA by a single phosphorodithioate linkage
- (2016) N. Dinuka Abeydeera et al. NUCLEIC ACIDS RESEARCH
- A general strategy for expanding polymerase function by droplet microfluidics
- (2016) Andrew C. Larsen et al. Nature Communications
- A Versatile Approach Towards Nucleobase-Modified Aptamers
- (2015) Fabian Tolle et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Hi-Fi SELEX: A high-fidelity digital-PCR based therapeutic aptamer discovery platform
- (2015) Eric Ouellet et al. BIOTECHNOLOGY AND BIOENGINEERING
- Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer® therapeutics
- (2015) Axel Vater et al. DRUG DISCOVERY TODAY
- Analysis of In Vitro Aptamer Selection Parameters
- (2015) Maureen McKeague et al. JOURNAL OF MOLECULAR EVOLUTION
- Sequence-Defined Scaffolding of Peptides on Nucleic Acid Polymers
- (2015) Chun Guo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Specific Inhibition of MicroRNA Processing Using l-RNA Aptamers
- (2015) Jonathan T. Sczepanski et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Reproducibility: Standardize antibodies used in research
- (2015) Andrew Bradbury et al. NATURE
- Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference–based bone anabolic strategy
- (2015) Chao Liang et al. NATURE MEDICINE
- Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers
- (2015) Alexander I Taylor et al. Nature Protocols
- NOX-A12: mobilizing CLL away from home
- (2014) R. Marasca et al. BLOOD
- Aptamers as Drug Delivery Vehicles
- (2014) Sven Kruspe et al. ChemMedChem
- Factor IXa as a target for anticoagulation in thrombotic disorders and conditions
- (2014) Dia A. Smiley et al. DRUG DISCOVERY TODAY
- An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents
- (2014) Stephanie E. Barrett et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Chemically Modified DNA Aptamers Bind Interleukin-6 with High Affinity and Inhibit Signaling by Blocking Its Interaction with Interleukin-6 Receptor
- (2014) Shashi Gupta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors
- (2014) Kyung-Ae Yang et al. Nature Chemistry
- Use of the REG1 anticoagulation system in patients with acute coronary syndromes undergoing percutaneous coronary intervention: results from the phase II RADAR-PCI study
- (2014) Thomas J. Povsic et al. EuroIntervention
- New Technologies Provide Quantum Changes in the Scale, Speed, and Success of SELEX Methods and Aptamer Characterization
- (2014) Abdullah Ozer et al. Molecular Therapy-Nucleic Acids
- Aptamer based electrochemical sensors for emerging environmental pollutants
- (2014) Akhtar Hayat et al. Frontiers in Chemistry
- A Brief History of G-Protein Coupled Receptors (Nobel Lecture)
- (2013) Robert J. Lefkowitz ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization
- (2013) J. Hoellenriegel et al. BLOOD
- Aptamers from Cell-Based Selection for Bioanalytical Applications
- (2013) Weihong Tan et al. CHEMICAL REVIEWS
- Directed polymerase evolution
- (2013) Tingjian Chen et al. FEBS LETTERS
- Generation of high-affinity DNA aptamers using an expanded genetic alphabet
- (2013) Michiko Kimoto et al. NATURE BIOTECHNOLOGY
- Finding the right antibody for the job
- (2013) Vivien Marx NATURE METHODS
- Calling the next generation of affinity reagents
- (2013) Vivien Marx NATURE METHODS
- In vitro selection with artificial expanded genetic information systems
- (2013) K. Sefah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Real-Time, Aptamer-Based Tracking of Circulating Therapeutic Agents in Living Animals
- (2013) B. S. Ferguson et al. Science Translational Medicine
- Aptamer-Based Analysis: A Promising Alternative for Food Safety Control
- (2013) Sonia Amaya-González et al. SENSORS
- In vivo SELEX for Identification of Brain-penetrating Aptamers
- (2013) Congsheng Cheng et al. Molecular Therapy-Nucleic Acids
- A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial
- (2012) Thomas J. Povsic et al. EUROPEAN HEART JOURNAL
- DNA Ligase-Mediated Translation of DNA Into Densely Functionalized Nucleic Acid Polymers
- (2012) Ryan Hili et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Functional In Vivo Delivery of Multiplexed Anti-HIV-1 siRNAs via a Chemically Synthesized Aptamer With a Sticky Bridge
- (2012) Jiehua Zhou et al. MOLECULAR THERAPY
- Selective transformations of complex molecules are enabled by aptameric protective groups
- (2012) Andreas A. Bastian et al. Nature Chemistry
- Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor
- (2012) Hanyang Yu et al. Nature Chemistry
- Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration
- (2012) Jeffrey S. Heier et al. OPHTHALMOLOGY
- Toward an Alternative Biology
- (2012) G. F. Joyce SCIENCE
- Synthetic Genetic Polymers Capable of Heredity and Evolution
- (2012) V. B. Pinheiro et al. SCIENCE
- Alternative affinity tools: more attractive than antibodies?
- (2011) Vincent J. B. Ruigrok et al. BIOCHEMICAL JOURNAL
- The Human Proteome Project: Current State and Future Direction
- (2011) Pierre Legrain et al. MOLECULAR & CELLULAR PROTEOMICS
- Challenges and opportunities for structural DNA nanotechnology
- (2011) Andre V. Pinheiro et al. Nature Nanotechnology
- Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration
- (2011) NEW ENGLAND JOURNAL OF MEDICINE
- RNA aptamers that functionally interact with green fluorescent protein and its derivatives
- (2011) Bo Shui et al. NUCLEIC ACIDS RESEARCH
- Unlocking Biomarker Discovery: Large Scale Application of Aptamer Proteomic Technology for Early Detection of Lung Cancer
- (2011) Rachel M. Ostroff et al. PLoS One
- Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery
- (2011) Larry Gold et al. PLoS One
- Model-Driven Engineering of RNA Devices to Quantitatively Program Gene Expression
- (2011) J. M. Carothers et al. SCIENCE
- Applications of Aptamers as Sensors
- (2010) Eun Jeong Cho et al. Annual Review of Analytical Chemistry
- Antibody validation
- (2010) Jennifer Bordeaux et al. BIOTECHNIQUES
- Expanding the Chemistry of DNA for in Vitro Selection
- (2010) Jonathan D. Vaught et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Molecular robots guided by prescriptive landscapes
- (2010) Kyle Lund et al. NATURE
- Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay
- (2010) Fernando Pastor et al. NATURE
- Aptamers as therapeutics
- (2010) Anthony D. Keefe et al. NATURE REVIEWS DRUG DISCOVERY
- The Chemical Biology of Aptamers
- (2009) Günter Mayer ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
- (2009) Nahum Sonenberg et al. CELL
- Creating Protein Affinity Reagents by Combining Peptide Ligands on Synthetic DNA Scaffolds
- (2009) Berea A. R. Williams et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- In vivo selection of tumor-targeting RNA motifs
- (2009) Jing Mi et al. Nature Chemical Biology
- Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells
- (2009) Jiehua Zhou et al. NUCLEIC ACIDS RESEARCH
- Emerging Concepts in the Immunopathogenesis of AIDS
- (2008) Daniel C. Douek et al. Annual Review of Medicine
- SELEX with modified nucleotides
- (2008) Anthony D Keefe et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- The Structure of a TNA−TNA Complex in Solution: NMR Study of the Octamer Duplex Derived from α-(l)-Threofuranosyl-(3′-2′)-CGAATTCG
- (2008) Marc-Olivier Ebert et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Adeno-associated Virus of a Single-polarity DNA Genome Is Capable of Transduction In Vivo
- (2008) Xiaohuai Zhou et al. MOLECULAR THERAPY
- Crystal structure of an RNA aptamer bound to thrombin
- (2008) S. B. Long et al. RNA
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