Cell death inhibitors protect against brain damage caused by cardiac ischemia/reperfusion injury

Cognitive impairment in myocardial infarction and heart failure

(2021) Kewarin Jinawong et al.   Acta Physiologica

An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo

(2021) Meike Hedwig Keuters et al.   Scientific Reports

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

BAX-dependent mitochondrial pathway mediates the crosstalk between ferroptosis and apoptosis

(2020) Young-Sun Lee et al.   APOPTOSIS

Metformin preferentially provides neuroprotection following cardiac ischemia/reperfusion in non-diabetic rats

(2020) Juthipong Benjanuwattra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial Fusion Promoter Alleviates Brain Damage in Rats with Cardiac Ischemia/Reperfusion Injury

(2020) Poomarin Surinkaew et al.   JOURNAL OF ALZHEIMERS DISEASE

Acyl‐CoA synthetase long chain family member 4 plays detrimental role in early brain injury after subarachnoid hemorrhage in rats by inducing ferroptosis

(2020) Xiao‐feng Qu et al.   CNS Neuroscience & Therapeutics

Pretreatment With PCSK9 Inhibitor Protects the Brain Against Cardiac Ischemia/Reperfusion Injury Through a Reduction of Neuronal Inflammation and Amyloid Beta Aggregation

(2019) Nattayaporn Apaijai et al.   Journal of the American Heart Association

Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

(2019) Yang Li et al.   CELL DEATH AND DIFFERENTIATION

Targeting RIPK1 for the treatment of human diseases

(2019) Alexei Degterev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory mechanisms leading to differential Acyl-CoA synthetase 4 expression in breast cancer cells

(2019) Melina A. Dattilo et al.   Scientific Reports

Association of Cognitive Impairment With Treatment and Outcomes in Older Myocardial Infarction Patients: A Report From the NCDR Chest Pain–MI Registry

(2019) Akshay Bagai et al.   Journal of the American Heart Association

Insight into the mechanism of ferroptosis inhibition by ferrostatin-1

(2019) Giovanni Miotto et al.   Redox Biology

Mitochondria, Oxidative Stress and the Kynurenine System, with a Focus on Ageing and Neuroprotection

(2018) Katalin Sas et al.   MOLECULES

Necrostatin-1 Attenuates Cisplatin-Induced Nephrotoxicity Through Suppression of Apoptosis and Oxidative Stress and Retains Klotho Expression

(2018) Yichun Ning et al.   Frontiers in Pharmacology

Hypoxic preconditioning attenuates necroptotic neuronal death induced by global cerebral ischemia via Drp1-dependent signaling pathway mediated by CaMKIIα inactivation in adult rats

(2018) Lixuan Zhan et al.   FASEB JOURNAL

BID links ferroptosis to mitochondrial cell death pathways

(2017) Sandra Neitemeier et al.   Redox Biology

Recent Advances in Pathophysiology of Traumatic Brain Injury

(2017) Parmeet Kaur et al.   Current Neuropharmacology

Humanin prevents brain mitochondrial dysfunction in a cardiac ischaemia-reperfusion injury model

(2016) Sirinart Kumfu et al.   EXPERIMENTAL PHYSIOLOGY

Monitoring cell-cell contactsin vivoin transgenic animals

(2016) Ting-Hao Huang et al.   JOURNAL OF CELL SCIENCE

Receptor-interacting protein kinase 3-mediated programmed cell necrosis in rats subjected to focal cerebral ischemia-reperfusion injury

(2016) YANRU DONG et al.   Molecular Medicine Reports

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Conivaptan, a Selective Arginine Vasopressin V1a and V2 Receptor Antagonist Attenuates Global Cerebral Edema Following Experimental Cardiac Arrest via Perivascular Pool of Aquaporin-4

(2016) Shin Nakayama et al.   Neurocritical Care

dAcsl, the Drosophila Ortholog of Acyl-CoA Synthetase Long-Chain Family Member 3 and 4, Inhibits Synapse Growth by Attenuating Bone Morphogenetic Protein Signaling via Endocytic Recycling

(2014) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Radiation-induced cytochrome c release and the neuroprotective effects of the pan-caspase inhibitor z-VAD-fmk in the hypoglossal nucleus

(2013) JIANGUO LI et al.   Experimental and Therapeutic Medicine

Necrosis-like death can engage multiple pro-apoptotic Bcl-2 protein family members

(2012) Denise Tischner et al.   APOPTOSIS

Necrostatin-1 Suppresses Autophagy and Apoptosis in Mice Traumatic Brain Injury Model

(2012) Yao-Qi Wang et al.   NEUROCHEMICAL RESEARCH

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

(2012) N Takahashi et al.   Cell Death & Disease

Drosophila Acyl-CoA Synthetase Long-Chain Family Member 4 Regulates Axonal Transport of Synaptic Vesicles and Is Required for Synaptic Development and Transmission

(2011) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-Induced Necrosis

(2011) K. M. Irrinki et al.   MOLECULAR AND CELLULAR BIOLOGY

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses

(2010) Pascale Krejbich-Trotot et al.   FASEB JOURNAL

Analyses of mental dysfunction-related ACSl4 in Drosophila reveal its requirement for Dpp/BMP production and visual wiring in the brain

(2009) Yi Zhang et al.   HUMAN MOLECULAR GENETICS

Transcription factor Sp1 dysregulation in Alzheimer's disease

(2008) Bruce A. Citron et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The XLMR gene ACSL4 plays a role in dendritic spine architecture

(2008) I. Meloni et al.   NEUROSCIENCE