标题
Injury-Induced Cellular Plasticity Drives Intestinal Regeneration
作者
关键词
Intestinal Homeostasis, Stem Cell Niche, Cellular Plasticity, Intestinal Regeneration
出版物
Cellular and Molecular Gastroenterology and Hepatology
Volume 13, Issue 3, Pages 843-856
出版商
Elsevier BV
发表日期
2021-12-13
DOI
10.1016/j.jcmgh.2021.12.005
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates
- (2021) Anika Böttcher et al. NATURE CELL BIOLOGY
- Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells
- (2021) Breanna J. Sheahan et al. Cellular and Molecular Gastroenterology and Hepatology
- Wnt and Src signals converge on YAP‐TEAD to drive intestinal regeneration
- (2021) Oriane Guillermin et al. EMBO JOURNAL
- Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient
- (2020) Neil McCarthy et al. Cell Stem Cell
- Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells
- (2020) Kazutaka Murata et al. Cell Stem Cell
- 5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation
- (2020) Santiago Uribe-Lewis et al. Scientific Reports
- Yap1-Driven Intestinal Repair Is Controlled by Group 3 Innate Lymphoid Cells
- (2020) Mónica Romera-Hernández et al. Cell Reports
- TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling
- (2020) Jason R. Goldsmith et al. Nature Communications
- Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium
- (2020) Thierry Jardé et al. Cell Stem Cell
- Cell death in the gut epithelium and implications for chronic inflammation
- (2020) Jay V. Patankar et al. Nature Reviews Gastroenterology & Hepatology
- Cycling Stem Cells Are Radioresistant and Regenerate the Intestine
- (2020) Xiaole Sheng et al. Cell Reports
- Elevating EGFR-MAPK program by a non-conventional Cdc42 enhances intestinal epithelial survival and regeneration
- (2020) Xiao Zhang et al. JCI Insight
- IL-13 secreted by ILC2s promotes the self-renewal of intestinal stem cells through circular RNA circPan3
- (2019) Pingping Zhu et al. NATURE IMMUNOLOGY
- Insulin-like Growth Factor II: An Essential Adult Stem Cell Niche Constituent in Brain and Intestine
- (2019) Amber N. Ziegler et al. Stem Cell Reports
- Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell
- (2019) Arshad Ayyaz et al. NATURE
- MET signaling overcomes EGFR inhibition in normal and colorectal cancer stem cells causing drug resistance
- (2019) Sander P.J. Joosten et al. GASTROENTEROLOGY
- Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion
- (2019) Johan H. van Es et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Paneth Cell Multipotency Induced by Notch Activation following Injury
- (2018) Shiyan Yu et al. Cell Stem Cell
- YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
- (2018) Shiro Yui et al. Cell Stem Cell
- Insulin/IGF-1 enhances intestinal epithelial crypt proliferation through PI3K/Akt, and not ERK signaling in obese humans
- (2018) Weinan Zhou et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Integrative multi‐omics analysis of intestinal organoid differentiation
- (2018) Rik GH Lindeboom et al. Molecular Systems Biology
- PDGFRα+pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo
- (2018) Gediminas Greicius et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Contribution of ATOH1 + Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium
- (2018) Fumiaki Ishibashi et al. Stem Cell Reports
- Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut
- (2018) Charles A. Herring et al. Cell Systems
- Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration
- (2018) Goran Tomic et al. Cell Stem Cell
- Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche
- (2018) Ysbrand M. Nusse et al. NATURE
- Subepithelial telocytes are an important source of Wnts that supports intestinal crypts
- (2018) Michal Shoshkes-Carmel et al. NATURE
- GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells
- (2018) Bahar Degirmenci et al. NATURE
- Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling
- (2018) Mark Schmitt et al. Cell Reports
- T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation
- (2018) Moshe Biton et al. CELL
- BHLHA15-positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice
- (2018) Yoku Hayakawa et al. GASTROENTEROLOGY
- MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms
- (2017) Sander P.J. Joosten et al. GASTROENTEROLOGY
- Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice
- (2017) Han-Byul Kim et al. GASTROENTEROLOGY
- Visualization and targeting of LGR5+ human colon cancer stem cells
- (2017) Mariko Shimokawa et al. NATURE
- Interplay between metabolic identities in the intestinal crypt supports stem cell function
- (2017) Maria J. Rodríguez-Colman et al. NATURE
- Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cells
- (2017) Juri Kazakevych et al. NUCLEIC ACIDS RESEARCH
- CD34+mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury
- (2017) Igor Stzepourginski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters
- (2016) Paul W. Tetteh et al. Cell Stem Cell
- Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium
- (2016) Hiroyuki Miyoshi et al. EMBO JOURNAL
- Mouse Label-Retaining Cells Are Molecularly and Functionally Distinct From Reserve Intestinal Stem Cells
- (2016) Ning Li et al. GASTROENTEROLOGY
- Epigenetic regulation of intestinal stem cells by Tet1-mediated DNA hydroxymethylation
- (2016) Rinho Kim et al. GENES & DEVELOPMENT
- Reg4+deep crypt secretory cells function as epithelial niche for Lgr5+stem cells in colon
- (2016) Nobuo Sasaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury
- (2016) Subhrajit Saha et al. Nature Communications
- Stem vs non-stem cell origin of colorectal cancer
- (2015) D J Huels et al. BRITISH JOURNAL OF CANCER
- Ascl2 Acts as an R-spondin/Wnt-Responsive Switch to Control Stemness in Intestinal Crypts
- (2015) Jurian Schuijers et al. Cell Stem Cell
- Krt19+/Lgr5− Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine
- (2015) Samuel Asfaha et al. Cell Stem Cell
- Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage
- (2015) Patricia Aparicio-Domingo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Opposing Activities of Notch and Wnt Signaling Regulate Intestinal Stem Cells and Gut Homeostasis
- (2015) Hua Tian et al. Cell Reports
- Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts
- (2014) Z. Kabiri et al. DEVELOPMENT
- Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele
- (2014) O. Basak et al. EMBO JOURNAL
- DNA methylation is required for the control of stem cell differentiation in the small intestine
- (2014) K. L. Sheaffer et al. GENES & DEVELOPMENT
- Long-lived intestinal tuft cells serve as colon cancer–initiating cells
- (2014) C. Benedikt Westphalen et al. JOURNAL OF CLINICAL INVESTIGATION
- Wnt Secretion from Epithelial Cells and Subepithelial Myofibroblasts Is Not Required in the Mouse Intestinal Stem Cell Niche In Vivo
- (2014) Adrianna K. San Roman et al. Stem Cell Reports
- Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration
- (2013) Ciara Metcalfe et al. Cell Stem Cell
- Intestinal label-retaining cells are secretory precursors expressing Lgr5
- (2013) Simon J. A. Buczacki et al. NATURE
- Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration
- (2013) Nick Barker NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus
- (2013) Lucas TJ Kaaij et al. GENOME BIOLOGY
- The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor
- (2012) Anne E. Powell et al. CELL
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
- (2012) Sarah Schwitalla et al. CELL
- Redundant Sources of Wnt Regulate Intestinal Stem Cells and Promote Formation of Paneth Cells
- (2012) Henner F. Farin et al. GASTROENTEROLOGY
- Crypt Base Columnar Stem Cells in Small Intestines of Mice Are Radioresistant
- (2012) Guoqiang Hua et al. GASTROENTEROLOGY
- Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease
- (2012) Alan M. Hanash et al. IMMUNITY
- Restriction of intestinal stem cell expansion and the regenerative response by YAP
- (2012) Evan R. Barry et al. NATURE
- Dll1+ secretory progenitor cells revert to stem cells upon crypt damage
- (2012) Johan H. van Es et al. NATURE CELL BIOLOGY
- Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)
- (2012) A. Durand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells
- (2012) T.-H. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A tissue-specific landscape of sense/antisense transcription in the mouse intestine
- (2011) Ulrich C Klostermeier et al. BMC GENOMICS
- Genetic Evidence That Intestinal Notch Functions Vary Regionally and Operate through a Common Mechanism of Math1 Repression
- (2011) Tae-Hee Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
- (2011) Hua Tian et al. NATURE
- Interconversion Between Intestinal Stem Cell Populations in Distinct Niches
- (2011) N. Takeda et al. SCIENCE
- Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells
- (2010) Hugo J. Snippert et al. CELL
- Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
- (2010) Toshiro Sato et al. NATURE
- Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells
- (2010) R. K. Montgomery et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift
- (2010) C. Lopez-Garcia et al. SCIENCE
- A genetic study of the role of the Wnt/β-catenin signalling in Paneth cell differentiation
- (2008) Pauline Andreu et al. DEVELOPMENTAL BIOLOGY
- Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation
- (2008) Liqin Zhu et al. NATURE
- Crypt stem cells as the cells-of-origin of intestinal cancer
- (2008) Nick Barker et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started