Transcriptional Networks Identify BRPF1 as a Potential Drug Target Based on Inflammatory Signature in Primary Lower-Grade Gliomas

Targeting p300/CBP axis in lethal prostate cancer

(2021) Jonathan Welti et al.   Cancer Discovery

Bromodomain-containing protein BRPF1 is a therapeutic target for liver cancer

(2021) Carol Lai-Hung Cheng et al.   Communications Biology

Epigenetic therapy inhibits metastases by disrupting premetastatic niches

(2020) Zhihao Lu et al.   NATURE

Landscape and function of multiple mutations within individual oncogenes

(2020) Yuki Saito et al.   NATURE

Phase and context shape the function of composite oncogenic mutations

(2020) Alexander N. Gorelick et al.   NATURE

BRPF1 ‐associated intellectual disability, ptosis, and facial dysmorphism in a multiplex family

(2019) Naomi Pode‐Shakked et al.   Molecular Genetics & Genomic Medicine

Bromodomains: a new target class for drug development

(2019) Andrea G. Cochran et al.   NATURE REVIEWS DRUG DISCOVERY

Novel BRPF1 mutation in a boy with intellectual disability, coloboma, facial nerve palsy and hypoplasia of the corpus callosum

(2019) Sofie Demeulenaere et al.   European Journal of Medical Genetics

Truncated BRPF1 Cooperates with Smoothened to Promote Adult Shh Medulloblastoma

(2019) Giuseppe Aiello et al.   Cell Reports

Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors

(2018) Xun Huang et al.   CELL

Primary brain tumours in adults

(2018) Sarah Lapointe et al.   LANCET

SJARACNe: a scalable software tool for gene network reverse engineering from big data

(2018) Alireza Khatamian et al.   BIOINFORMATICS

A novel systemic inflammation response index (SIRI) for predicting postoperative survival of patients with esophageal squamous cell carcinoma

(2018) Yiting Geng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A Prognostic Signature for Lower Grade Gliomas Based on Expression of Long Non-Coding RNAs

(2018) Manjari Kiran et al.   MOLECULAR NEUROBIOLOGY

European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

(2017) Michael Weller et al.   LANCET ONCOLOGY

A mathematical model describes the malignant transformation of low grade gliomas: Prognostic implications

(2017) Magdalena U. Bogdańska et al.   PLoS One

Epigenetic plasticity and the hallmarks of cancer

(2017) William A. Flavahan et al.   SCIENCE

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer

(2016) Anna C. Groner et al.   CANCER CELL

Nomograms for predicting prognostic value of inflammatory biomarkers in colorectal cancer patients after radical resection

(2016) Yaqi Li et al.   INTERNATIONAL JOURNAL OF CANCER

MOZ and MORF acetyltransferases: Molecular interaction, animal development and human disease

(2015) Xiang-Jiao Yang   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Deficiency of the Chromatin Regulator Brpf1 Causes Abnormal Brain Development

(2015) Linya You et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Survival and low-grade glioma: the emergence of genetic information

(2015) Elizabeth B. Claus et al.   Neurosurgical Focus

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis

(2015) Xi Feng et al.   Oncotarget

International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading

(2014) David N. Louis et al.   BRAIN PATHOLOGY

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

(2014) Irfan A. Asangani et al.   NATURE

Practice changing mature results of RTOG study 9802: another positive PCV trial makes adjuvant chemotherapy part of standard of care in low-grade glioma

(2014) M. J. van den Bent   NEURO-ONCOLOGY

The cellular and molecular origin of tumor-associated macrophages

(2014) R. A. Franklin et al.   SCIENCE

Targeted Therapy in Gliomas

(2014) Mohamed Ali Hamza et al.   Current Oncology Reports

Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity

(2013) M.-E. Lalonde et al.   GENES & DEVELOPMENT

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010

(2013) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation

(2013) W. Wick et al.   NEUROLOGY

PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

(2012) Weiwei Yang et al.   CELL

Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice

(2012) M. Weller et al.   NEURO-ONCOLOGY

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

Neutrophil-to-lymphocyte ratio associated with mortality in early hepatocellular carcinoma patients after radiofrequency ablation

(2011) Tsung-Ming Chen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Low-grade gliomas in adults

(2011) Nader Sanai et al.   JOURNAL OF NEUROSURGERY

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

(2010) Christian Hartmann et al.   ACTA NEUROPATHOLOGICA

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Molecular Architecture of Quartet MOZ/MORF Histone Acetyltransferase Complexes

(2008) M. Ullah et al.   MOLECULAR AND CELLULAR BIOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE