Deficiency of the Chromatin Regulator Brpf1 Causes Abnormal Brain Development

Engrailed-2 protein as a potential urinary prostate cancer biomarker

(2015) Michał Piotr Marszałł et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

An individual with blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) and additional features expands the phenotype associated with mutations inKAT6B

(2014) Hung-Chun Yu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

(2014) Marcel Kool et al.   CANCER CELL

Expression atlas of the multivalent epigenetic regulator Brpf1 and its requirement for survival of mouse embryos

(2014) Linya You et al.   Epigenetics

Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain

(2014) Mulu Y. Lubula et al.   FEBS LETTERS

The role of chromatin modifiers in normal and malignant hematopoiesis

(2013) J. S. Butler et al.   BLOOD

Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity

(2013) M.-E. Lalonde et al.   GENES & DEVELOPMENT

Mice Lacking α-Tubulin Acetyltransferase 1 Are Viable but Display α-Tubulin Acetylation Deficiency and Dentate Gyrus Distortion

(2013) Go-Woon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Tumor Suppressor Kinase LKB1 Activates the Downstream Kinases SIK2 and SIK3 to Stimulate Nuclear Export of Class IIa Histone Deacetylases

(2013) Donald R. Walkinshaw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exome sequencing to identify de novo mutations in sporadic ALS trios

(2013) Alessandra Chesi et al.   NATURE NEUROSCIENCE

From neural development to cognition: unexpected roles for chromatin

(2013) Jehnna L. Ronan et al.   NATURE REVIEWS GENETICS

MOZ-Mediated Repression ofp16INK4aIs Critical for the Self-Renewal of Neural and Hematopoietic Stem Cells

(2013) Flor M. Perez-Campo et al.   STEM CELLS

De Novo Mutations of the Gene Encoding the Histone Acetyltransferase KAT6B Cause Genitopatellar Syndrome

(2012) Michael A. Simpson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome

(2012) Philippe M. Campeau et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cancer Genetics and Epigenetics: Two Sides of the Same Coin?

(2012) Jueng Soo You et al.   CANCER CELL

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex

(2012) G. Mairet-Coello et al.   DEVELOPMENT

MOZ Regulates the Tbx1 Locus, and Moz Mutation Partially Phenocopies DiGeorge Syndrome

(2012) Anne K. Voss et al.   DEVELOPMENTAL CELL

TheKAT6B-related disorders genitopatellar syndrome and Ohdo/SBBYS syndrome have distinct clinical features reflecting distinct molecular mechanisms

(2012) Philippe M. Campeau et al.   HUMAN MUTATION

Clonal selection drives genetic divergence of metastatic medulloblastoma

(2012) Xiaochong Wu et al.   NATURE

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

Epigenetic mechanisms in neurological disease

(2012) Mira Jakovcevski et al.   NATURE MEDICINE

A Cascade of Morphogenic Signaling Initiated by the Meninges Controls Corpus Callosum Formation

(2012) Youngshik Choe et al.   NEURON

Whole-Exome-Sequencing Identifies Mutations in Histone Acetyltransferase Gene KAT6B in Individuals with the Say-Barber-Biesecker Variant of Ohdo Syndrome

(2011) Jill Clayton-Smith et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Signals and Combinatorial Functions of Histone Modifications

(2011) Tamaki Suganuma et al.   Annual Review of Biochemistry

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis

(2011) Y. Mishima et al.   BLOOD

Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome–like phenotype and hyperactivated MAPK signaling in humans and mice

(2011) Michael Kraft et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural and Histone Binding Ability Characterizations of Human PWWP Domains

(2011) Hong Wu et al.   PLoS One

Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure

(2011) Laurent Sansregret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haploinsufficiency of HDAC4 Causes Brachydactyly Mental Retardation Syndrome, with Brachydactyly Type E, Developmental Delays, and Behavioral Problems

(2010) Stephen R. Williams et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

(2010) Alessandro Vezzoli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of high-quality cancer prognostic markers and metastasis network modules

(2010) Jie Li et al.   Nature Communications

Mouse H6 Homeobox 1 (Hmx1) mutations cause cranial abnormalities and reduced body mass

(2009) Robert J Munroe et al.   BMC DEVELOPMENTAL BIOLOGY

Osteocrin – Beyond just another bone protein?

(2009) P. Moffatt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Brpf1, a subunit of the MOZ histone acetyl transferase complex, maintains expression of anterior and posterior Hox genes for proper patterning of craniofacial and caudal skeletons

(2009) Kenta Hibiya et al.   DEVELOPMENTAL BIOLOGY

Moz and Retinoic Acid Coordinately Regulate H3K9 Acetylation, Hox Gene Expression, and Segment Identity

(2009) Anne K. Voss et al.   DEVELOPMENTAL CELL

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

(2009) Rocio G Urdinguio et al.   LANCET NEUROLOGY

Understanding the Mechanisms of Callosal Development Through the Use of Transgenic Mouse Models

(2009) Amber-Lee S. Donahoo et al.   Seminars in Pediatric Neurology

The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity

(2008) K. Laue et al.   DEVELOPMENT

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone

(2008) S. J. Arnold et al.   GENES & DEVELOPMENT

Molecular Architecture of Quartet MOZ/MORF Histone Acetyltransferase Complexes

(2008) M. Ullah et al.   MOLECULAR AND CELLULAR BIOLOGY

Development of the human cerebral cortex: Boulder Committee revisited

(2008) Irina Bystron et al.   NATURE REVIEWS NEUROSCIENCE

Tbr2 Directs Conversion of Radial Glia into Basal Precursors and Guides Neuronal Amplification by Indirect Neurogenesis in the Developing Neocortex

(2008) Alessandro Sessa et al.   NEURON

Insulinoma-Associated 1 Has a Panneurogenic Role and Promotes the Generation and Expansion of Basal Progenitors in the Developing Mouse Neocortex

(2008) Lilla M. Farkas et al.   NEURON