TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus
出版年份 2021 全文链接
标题
TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus
作者
关键词
-
出版物
Acta Neuropathologica Communications
Volume 9, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-10-10
DOI
10.1186/s40478-021-01264-w
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- O-GlcNAcylation ameliorates the pathological manifestations of Alzheimer’s disease by inhibiting necroptosis
- (2021) Jinsu Park et al. Science Advances
- Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter
- (2021) Carmen Picon et al. ACTA NEUROPATHOLOGICA
- The PKR/P38/RIPK1 Signaling Pathway as a Therapeutic Target in Alzheimer’s Disease
- (2021) Jacques Hugon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Apoptotic Pathways and Alzheimer’s Disease: Probing Therapeutic Potential
- (2021) Vivek Kumar Sharma et al. NEUROCHEMICAL RESEARCH
- Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease
- (2020) David Gate et al. NATURE
- Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis
- (2020) Ting Zhang et al. CELL
- Selective Targeting of TNF Receptors as a Novel Therapeutic Approach
- (2020) Roman Fischer et al. Frontiers in Cell and Developmental Biology
- Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target
- (2020) Lauren Mifflin et al. NATURE REVIEWS DRUG DISCOVERY
- Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
- (2020) Renato Socodato et al. Cell Reports
- Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
- (2020) Fangda Leng et al. Nature Reviews Neurology
- Lessons learned from CHMP2B, implications for frontotemporal dementia and amyotrophic lateral sclerosis
- (2020) Chris Ugbode et al. NEUROBIOLOGY OF DISEASE
- Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier
- (2020) Patricia Gallego-Delgado et al. PLOS BIOLOGY
- CD8+ T Cell-Mediated Mechanisms Contribute to the Progression of Neurocognitive Impairment in Both Multiple Sclerosis and Alzheimer's Disease?
- (2020) Zorica Stojić-Vukanić et al. Frontiers in Immunology
- Sex Differences in Alzheimer’s Disease: Understanding the Molecular Impact
- (2019) Carlos A. Toro et al. BRAIN RESEARCH
- MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration
- (2019) Qiong Feng et al. Autophagy
- DNL 104, a Centrally Penetrant RIPK 1 Inhibitor, Inhibits RIP 1 Kinase Phosphorylation in a Randomized Phase I Ascending Dose Study in Healthy Volunteers
- (2019) Hendrika W. Grievink et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis
- (2019) Melanie Fritsch et al. NATURE
- Necrosome complex detected in granulovacuolar degeneration is associated with neuronal loss in Alzheimer’s disease
- (2019) Marta J. Koper et al. ACTA NEUROPATHOLOGICA
- Meningeal inflammation changes the balance of TNF signalling in cortical grey matter in multiple sclerosis
- (2019) Roberta Magliozzi et al. Journal of Neuroinflammation
- Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
- (2019) Najoua Lalaoui et al. NATURE
- Microglial microRNAs mediate sex-specific responses to tau pathology
- (2019) Lay Kodama et al. NATURE NEUROSCIENCE
- TNF-α Increases Production of Reactive Oxygen Species through Cdk5 Activation in Nociceptive Neurons
- (2018) Rodrigo Sandoval et al. Frontiers in Physiology
- Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases
- (2018) Junying Yuan et al. NATURE REVIEWS NEUROSCIENCE
- MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation
- (2017) Seongmin Yoon et al. IMMUNITY
- An Inflammatory Perspective on Necroptosis
- (2017) Conor J. Kearney et al. MOLECULAR CELL
- Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis
- (2017) Beata E. Mierzwa et al. NATURE CELL BIOLOGY
- Necroptosis activation in Alzheimer's disease
- (2017) Antonella Caccamo et al. NATURE NEUROSCIENCE
- Caspase-8, association with Alzheimer’s Disease and functional analysis of rare variants
- (2017) Jan Rehker et al. PLoS One
- RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
- (2017) Yingying Zhang et al. Nature Communications
- Regional and Gender Study of Neuronal Density in Brain during Aging and in Alzheimer's Disease
- (2016) Eva Martínez-Pinilla et al. Frontiers in Aging Neuroscience
- TNF-alpha G308A Polymorphism and the Susceptibility to Alzheimer's Disease: An Updated Meta-analysis
- (2015) Tengfei Wang ARCHIVES OF MEDICAL RESEARCH
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- Exploring the origins of grey matter damage in multiple sclerosis
- (2015) Massimiliano Calabrese et al. NATURE REVIEWS NEUROSCIENCE
- Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death
- (2015) B Schenk et al. ONCOGENE
- Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF
- (2015) Roman Fischer et al. Oxidative Medicine and Cellular Longevity
- Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains
- (2015) Douglas G. Walker et al. Alzheimers Research & Therapy
- Activation of Necroptosis in Multiple Sclerosis
- (2015) Dimitry Ofengeim et al. Cell Reports
- Regulated Cell Death: Signaling and Mechanisms
- (2014) Avi Ashkenazi et al. Annual Review of Cell and Developmental Biology
- Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity
- (2014) Gabriel Olmos et al. MEDIATORS OF INFLAMMATION
- Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS
- (2014) Diane B. Re et al. NEURON
- Necroptosis in health and diseases
- (2014) Wen Zhou et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- Programmed necrosis, not apoptosis, is a key mediator of cell loss and DAMP-mediated inflammation in dsRNA-induced retinal degeneration
- (2013) Y Murakami et al. CELL DEATH AND DIFFERENTIATION
- TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys
- (2013) Mychael V. Lourenco et al. Cell Metabolism
- Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death
- (2013) Dimitry Ofengeim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- CYLD Deubiquitinates RIP1 in the TNFα-Induced Necrosome to Facilitate Kinase Activation and Programmed Necrosis
- (2013) David M. Moquin et al. PLoS One
- The FLIP Side of Life
- (2013) J. Silke et al. Science Signaling
- Selection of novel reference genes for use in the human central nervous system: a BrainNet Europe Study
- (2012) Pascal F. Durrenberger et al. ACTA NEUROPATHOLOGICA
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- Charged Multivesicular Body Protein 2B (CHMP2B) of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III) Polymerizes into Helical Structures Deforming the Plasma Membrane
- (2011) Gilles Bodon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RIP3 mediates the embryonic lethality of caspase-8-deficient mice
- (2011) William J. Kaiser et al. NATURE
- Programmed necrosis: backup to and competitor with apoptosis in the immune system
- (2011) Jiahuai Han et al. NATURE IMMUNOLOGY
- Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism
- (2011) Gunjan Dhawan et al. NEUROBIOLOGY OF AGING
- Sex differences in grey matter atrophy patterns among AD and aMCI patients: Results from ADNI
- (2011) Martha Skup et al. NEUROIMAGE
- A Meta-Analysis of Cytokines in Alzheimer's Disease
- (2010) Walter Swardfager et al. BIOLOGICAL PSYCHIATRY
- Molecular mechanisms of necroptosis: an ordered cellular explosion
- (2010) Peter Vandenabeele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Immunopositivity for ESCRT-III subunit CHMP2B in granulovacuolar degeneration of neurons in the Alzheimer's disease hippocampus
- (2010) Yuu Yamazaki et al. NEUROSCIENCE LETTERS
- RIP Kinases at the Crossroads of Cell Death and Survival
- (2009) Wim Declercq et al. CELL
- Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
- (2009) Sudan He et al. CELL
- A New C-Terminal Cleavage Product of Procaspase-8, p30, Defines an Alternative Pathway of Procaspase-8 Activation
- (2009) J. C. Hoffmann et al. MOLECULAR AND CELLULAR BIOLOGY
- The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
- (2009) Camilla Raiborg et al. NATURE
- Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease
- (2009) Emily R. Rosario et al. NEUROBIOLOGY OF AGING
- Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice
- (2008) Michelle C. Janelsins et al. AMERICAN JOURNAL OF PATHOLOGY
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation