Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier

Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration

(2020) Rachel E. James et al.   Acta Neuropathologica Communications

Saltatory Conduction along Myelinated Axons Involves a Periaxonal Nanocircuit

(2019) Charles C.H. Cohen et al.   CELL

Meningeal inflammation changes the balance of TNF signalling in cortical grey matter in multiple sclerosis

(2019) Roberta Magliozzi et al.   Journal of Neuroinflammation

Inflammatory intrathecal profiles and cortical damage in multiple sclerosis

(2018) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

The Axon-Myelin Unit in Development and Degenerative Disease

(2018) Ruth M. Stassart et al.   Frontiers in Neuroscience

Regulation of myelin structure and conduction velocity by perinodal astrocytes

(2018) Dipankar J. Dutta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects of paranodal myelin damage on action potential depend on axonal structure

(2017) Ehsan Daneshi Kohan et al.   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

The molecular physiology of the axo-myelinic synapse

(2016) Ileana Micu et al.   EXPERIMENTAL NEUROLOGY

The myelinated fiber loss in the corpus callosum of mouse model of schizophrenia induced by MK-801

(2015) Yun Xiu et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Differential modulation of the juxtaparanodal complex in Multiple Sclerosis

(2015) Maria E. Kastriti et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

IFN-γ ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation

(2015) Rebecca A. Sosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-γ and alpha B-crystallin

(2014) Malika Bsibsi et al.   ACTA NEUROPATHOLOGICA

The node of Ranvier in CNS pathology

(2014) I. Lorena Arancibia-Carcamo et al.   ACTA NEUROPATHOLOGICA

In vivo evidence of glutamate toxicity in multiple sclerosis

(2014) Christina J. Azevedo et al.   ANNALS OF NEUROLOGY

Distribution of axon diameters in cortical white matter: an electron-microscopic study on three human brains and a macaque

(2014) Daniel Liewald et al.   BIOLOGICAL CYBERNETICS

A scoping review of rehabilitation interventions that reduce fatigue among adults with multiple sclerosis

(2014) Miho Asano et al.   DISABILITY AND REHABILITATION

A unified cell biological perspective on axon–myelin injury

(2014) Mikael Simons et al.   JOURNAL OF CELL BIOLOGY

Primary paranode demyelination modulates slowly developing axonal depolarization in a model of axonal injury

(2014) Vladislav Volman et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

(2014) Manuel A. Friese et al.   Nature Reviews Neurology

Saltatory conduction in unmyelinated axons: clustering of Na+ channels on lipid rafts enables micro-saltatory conduction in C-fibers

(2014) Ali Neishabouri et al.   Frontiers in Neuroanatomy

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons

(2013) Shailender Singh et al.   ACTA NEUROPATHOLOGICA

Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats

(2013) Christopher Gardner et al.   BRAIN

Membrane domain organization of myelinated axons requires βII spectrin

(2013) Chuansheng Zhang et al.   JOURNAL OF CELL BIOLOGY

Computer Modeling of Mild Axonal Injury: Implications for Axonal Signal Transmission

(2013) Vladislav Volman et al.   NEURAL COMPUTATION

Increased Concentrations of Glutamate and Glutamine in Normal-Appearing White Matter of Patients with Multiple Sclerosis and Normal MR Imaging Brain Scans

(2013) Anders Tisell et al.   PLoS One

Subtle Paranodal Injury Slows Impulse Conduction in a Mathematical Model of Myelinated Axons

(2013) Charles F. Babbs et al.   PLoS One

Coupled left-shift of Nav channels: modeling the Na+-loading and dysfunctional excitability of damaged axons

(2012) Pierre-Alexandre Boucher et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

The neuropathological basis of clinical progression in multiple sclerosis

(2011) Richard Reynolds et al.   ACTA NEUROPATHOLOGICA

Multiple sclerosis normal-appearing white matter: Pathology-imaging correlations

(2011) Natalia M. Moll et al.   ANNALS OF NEUROLOGY

Paranodal myelin retraction in relapsing experimental autoimmune encephalomyelitis visualized by coherent anti-Stokes Raman scattering microscopy

(2011) Yan Fu et al.   JOURNAL OF BIOMEDICAL OPTICS

Explaining pathological changes in axonal excitability through dynamical analysis of conductance-based models

(2011) Jay S Coggan et al.   Journal of Neural Engineering

The Cytoskeletal Adaptor Protein Band 4.1B Is Required for the Maintenance of Paranodal Axoglial Septate Junctions in Myelinated Axons

(2011) E. D. Buttermore et al.   JOURNAL OF NEUROSCIENCE

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Real-Time CARS Imaging Reveals a Calpain-Dependent Pathway for Paranodal Myelin Retraction during High-Frequency Stimulation

(2011) Terry B. Huff et al.   PLoS One

Protein 4.1B Contributes to the Organization of Peripheral Myelinated Axons

(2011) Carmen Cifuentes-Diaz et al.   PLoS One

A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis

(2010) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

Activated Microglia Mediate Axoglial Disruption That Contributes to Axonal Injury in Multiple Sclerosis

(2010) Owain W. Howell et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Permeability of the Paranodal Junction of Myelinated Nerve Fibers

(2010) A. Mierzwa et al.   JOURNAL OF NEUROSCIENCE

Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways

(2010) Caterina Veroni et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Myelination and support of axonal integrity by glia

(2010) Klaus-Armin Nave   NATURE

Visualization of cytoplasmic diffusion within living myelin sheaths of CNS white matter axons using microinjection of the fluorescent dye Lucifer Yellow

(2010) Alexander A. Velumian et al.   NEUROIMAGE

A model of tight junction function in central nervous system myelinated axons

(2010) Alexander Gow et al.   Neuron Glia Biology

Internodal myelination during development quantitated using X-ray diffraction

(2009) Deepika Agrawal et al.   JOURNAL OF STRUCTURAL BIOLOGY

Glutamate Excitotoxicity Inflicts Paranodal Myelin Splitting and Retraction

(2009) Yan Fu et al.   PLoS One

Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system

(2008) Barbara Zonta et al.   JOURNAL OF CELL BIOLOGY

Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitors

(2008) Izumi Yawata et al.   LIFE SCIENCES