Lessons learned from CHMP2B, implications for frontotemporal dementia and amyotrophic lateral sclerosis
出版年份 2020 全文链接
标题
Lessons learned from CHMP2B, implications for frontotemporal dementia and amyotrophic lateral sclerosis
作者
关键词
Neurodegeneration, Therapeutics, Immunity, Proteostasis, FTD, ALS, ESCRT, Motor neurone disease, CHMP2B
出版物
NEUROBIOLOGY OF DISEASE
Volume 147, Issue -, Pages 105144
出版商
Elsevier BV
发表日期
2020-11-02
DOI
10.1016/j.nbd.2020.105144
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Activation of the Notch Signaling Pathway and Cellular Localization of Notch Signaling Molecules in the Spinal Cord of SOD1-G93A ALS Model Mice
- (2020) Chong Liu et al. NEUROSCIENCE
- Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation
- (2020) Aurélie Bertin et al. Nature Communications
- Protein Aggregation and Dysfunction of Autophagy-Lysosomal Pathway: A Vicious Cycle in Lysosomal Storage Diseases
- (2020) Antonio Monaco et al. Frontiers in Molecular Neuroscience
- Retrovirus reactivation in CHMP2BIntron5 models of frontotemporal dementia
- (2020) Laura Fort-Aznar et al. HUMAN MOLECULAR GENETICS
- Neuroprotective activity of ursodeoxycholic acid in CHMP2B models of frontotemporal dementia
- (2020) Ryan J.H. West et al. NEUROBIOLOGY OF DISEASE
- Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila
- (2020) Yubing Lu et al. Scientific Reports
- The Relevancy of Data Regarding the Metabolism of Iron to Our Understanding of Deregulated Mechanisms in ALS; Hypotheses and Pitfalls
- (2019) Camille Petillon et al. Frontiers in Neuroscience
- Disrupted neuronal trafficking in amyotrophic lateral sclerosis
- (2019) Katja Burk et al. ACTA NEUROPATHOLOGICA
- Notch Signalling in the Hippocampus of Patients With Motor Neuron Disease
- (2019) Ulises Gómez-Pinedo et al. Frontiers in Neuroscience
- Safety and tolerability of Triumeq in amyotrophic lateral sclerosis: the Lighthouse trial
- (2019) Julian Gold et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Impact of Autophagy and Aging on Iron Load and Ferritin in Drosophila Brain
- (2019) Anne-Claire Jacomin et al. Frontiers in Cell and Developmental Biology
- Expression of a human variant of CHMP2B linked to neurodegeneration in Drosophila external sensory organs leads to cell fate transformations associated with increased Notch activity
- (2019) Caroline Wilson et al. Developmental Neurobiology
- Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation
- (2019) John J. Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dysregulation of AMPA receptor subunit expression in sporadic ALS post‐mortem brain
- (2019) Jenna M Gregory et al. JOURNAL OF PATHOLOGY
- Clinical features and dysfunctions of iron metabolism in Parkinson disease patients with hyper echogenicity in substantia nigra: a cross-sectional study
- (2018) Shu-yang Yu et al. BMC Neurology
- The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia
- (2018) Ryan J H West et al. HUMAN MOLECULAR GENETICS
- Targeted next-generation sequencing reveals novel and rare variants in Indian patients with amyotrophic lateral sclerosis
- (2018) Priyam Narain et al. NEUROBIOLOGY OF AGING
- The role of ESCRT during development and functioning of the nervous system
- (2018) Rémy Sadoul et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease
- (2018) Simon M. Bell et al. JOURNAL OF MOLECULAR BIOLOGY
- Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis
- (2018) Annelies Nonneman et al. NEUROBIOLOGY OF DISEASE
- Inflammation in ALS/FTD pathogenesis
- (2018) Madelyn E. McCauley et al. ACTA NEUROPATHOLOGICA
- Non-transferrin-bound iron transporters
- (2018) Mitchell D. Knutson FREE RADICAL BIOLOGY AND MEDICINE
- Mechanisms of AMPA Receptor Endosomal Sorting
- (2018) Gabrielle T. Parkinson et al. Frontiers in Molecular Neuroscience
- Endocytosis regulates TDP-43 toxicity and turnover
- (2017) Guangbo Liu et al. Nature Communications
- Human Endogenous Retrovirus-K and TDP-43 Expression Bridges ALS and HIV Neuropathology
- (2017) Renée N. Douville et al. Frontiers in Microbiology
- Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B
- (2017) Yu Zhang et al. Stem Cell Reports
- Coiled-coils: The long and short of it
- (2016) Linda Truebestein et al. BIOESSAYS
- The role of CHMP2BIntron5 in autophagy and frontotemporal dementia
- (2016) Christopher S. Krasniak et al. BRAIN RESEARCH
- The ESCRT machinery: new roles at new holes
- (2016) Y Olmos et al. CURRENT OPINION IN CELL BIOLOGY
- A transgenic mouse expressing CHMP2Bintron5mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia
- (2016) Aurélia Vernay et al. HUMAN MOLECULAR GENETICS
- ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
- (2016) Liliane Christ et al. JOURNAL OF CELL BIOLOGY
- Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
- (2016) Benjamin Richter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms linking circadian clocks, sleep, and neurodegeneration
- (2016) Erik S. Musiek et al. SCIENCE
- Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology
- (2015) Emma L. Clayton et al. ACTA NEUROPATHOLOGICA
- FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions
- (2015) Dejun Yang et al. ACTA NEUROPATHOLOGICA
- Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay
- (2015) Sonja Aits et al. Autophagy
- Rab8, POSH, and TAK1 regulate synaptic growth in aDrosophilamodel of frontotemporal dementia
- (2015) Ryan J.H. West et al. JOURNAL OF CELL BIOLOGY
- Regulation of Postsynaptic Function by the Dementia-Related ESCRT-III Subunit CHMP2B
- (2015) R. Chassefeyre et al. JOURNAL OF NEUROSCIENCE
- UDCA exerts beneficial effect on mitochondrial dysfunction inLRRK2G2019Scarriers and in vivo
- (2015) Heather Mortiboys et al. NEUROLOGY
- Notch pathway is activated in cell culture and mouse models of mutant SOD1-related familial amyotrophic lateral sclerosis, with suppression of its activation as an additional mechanism of neuroprotection for lithium and valproate
- (2015) S.-Y. Wang et al. NEUROSCIENCE
- Human endogenous retrovirus-K contributes to motor neuron disease
- (2015) Wenxue Li et al. Science Translational Medicine
- Roles of ESCRT in autophagy-associated neurodegeneration
- (2014) Jin-A Lee et al. Autophagy
- ESCRT Function in Cytokinesis: Location, Dynamics and Regulation by Mitotic Kinases
- (2014) Musab Bhutta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Iron dysregulation in Huntington's disease
- (2014) Michelle Muller et al. JOURNAL OF NEUROCHEMISTRY
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia
- (2014) Eduardo Gascon et al. NATURE MEDICINE
- 'The clocks that time us'—circadian rhythms in neurodegenerative disorders
- (2014) Aleksandar Videnovic et al. Nature Reviews Neurology
- The machinery of macroautophagy
- (2013) Yuchen Feng et al. CELL RESEARCH
- Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury
- (2013) Ikuko Maejima et al. EMBO JOURNAL
- Expression of mutant CHMP2B, an ESCRT-III component involved in frontotemporal dementia, causes eye deformities due to Notch misregulation in Drosophila
- (2013) Abigael Cheruiyot et al. FASEB JOURNAL
- Syntaxin 13, a Genetic Modifier of Mutant CHMP2B in Frontotemporal Dementia, Is Required for Autophagosome Maturation
- (2013) Yubing Lu et al. MOLECULAR CELL
- Rare autosomal copy number variations in early-onset familial Alzheimer’s disease
- (2013) B V Hooli et al. MOLECULAR PSYCHIATRY
- The functional analysis of the CHMP2B missense mutation associated with neurodegenerative diseases in the endo-lysosomal pathway
- (2012) Jeong-Ho Han et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice
- (2012) Shabnam Ghazi-Noori et al. BRAIN
- The ESCRT machinery
- (2012) Oliver Schmidt et al. CURRENT BIOLOGY
- Differential requirements of mammalian ESCRTs in multivesicular body formation, virus budding and cell division
- (2012) Eiji Morita FEBS Journal
- Reversal of pathology in CHMP2B-mediated frontotemporal dementia patient cells using RNA interference
- (2012) Troels Tolstrup Nielsen et al. JOURNAL OF GENE MEDICINE
- Genetic Overlap between Apparently Sporadic Motor Neuron Diseases
- (2012) Marka van Blitterswijk et al. PLoS One
- Structural Basis for Microtubule Binding and Release by Dynein
- (2012) W. B. Redwine et al. SCIENCE
- The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study
- (2011) Julie Phukan et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Autophagy in Spinal Cord Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis
- (2011) Shoichi Sasaki JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- ESCRT Machinery and Cytokinesis: the Road to Daughter Cell Separation
- (2011) Anna Caballe et al. TRAFFIC
- Ursodeoxycholic acid modulates the ubiquitin-proteasome degradation pathway of p53
- (2010) Joana D. Amaral et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations
- (2010) Hazel Urwin et al. HUMAN MOLECULAR GENETICS
- CHMP2B mutants linked to frontotemporal dementia impair maturation of dendritic spines
- (2010) A. Belly et al. JOURNAL OF CELL SCIENCE
- CHMP2B mutations are rare in French families with frontotemporal lobar degeneration
- (2010) Mustapha Ghanim et al. JOURNAL OF NEUROLOGY
- AMPA receptor-mediated neuronal death in sporadic ALS
- (2010) Shin Kwak et al. NEUROPATHOLOGY
- Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS)
- (2010) Laura E. Cox et al. PLoS One
- Identification of casein kinase-1 phosphorylation sites on TDP-43
- (2009) Fuyuki Kametani et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Structure and function of ESCRT-III: Table 1
- (2009) Suman Lata et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The ESCRT machinery: new functions in viral and cellular biology
- (2009) Jeremy G. Carlton et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release
- (2009) Jörg Votteler et al. BMC BIOCHEMISTRY
- How do ESCRT proteins control autophagy?
- (2009) T. E. Rusten et al. JOURNAL OF CELL SCIENCE
- Inhibition of Autophagy Induction Delays Neuronal Cell Loss Caused by Dysfunctional ESCRT-III in Frontotemporal Dementia
- (2009) J.-A Lee et al. JOURNAL OF NEUROSCIENCE
- Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia
- (2009) S. T. Ahmad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
- (2008) Masato Hasegawa et al. ANNALS OF NEUROLOGY
- Lysosomes in iron metabolism, ageing and apoptosis
- (2008) Tino Kurz et al. HISTOCHEMISTRY AND CELL BIOLOGY
- A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
- (2008) J. D. Cahoy et al. JOURNAL OF NEUROSCIENCE
- Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate
- (2008) A. L. McCormick et al. NEUROLOGY
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