Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis
出版年份 2021 全文链接
标题
Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis
作者
关键词
PDAC, AXL, Pancreas, Biomarker, Differential diagnosis
出版物
EBioMedicine
Volume 75, Issue -, Pages 103797
出版商
Elsevier BV
发表日期
2021-12-29
DOI
10.1016/j.ebiom.2021.103797
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cancer Statistics, 2021
- (2021) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target
- (2021) Pier Paolo Sainaghi et al. DISEASE MARKERS
- Blood biomarkers for differential diagnosis and early detection of pancreatic cancer
- (2021) Fawaz N. Al-Shaheri et al. CANCER TREATMENT REVIEWS
- AXL Is a Key Factor for Cell Plasticity and Promotes Metastasis in Pancreatic Cancer
- (2021) Wenting Du et al. MOLECULAR CANCER RESEARCH
- Non-Invasive Biomarkers for Earlier Detection of Pancreatic Cancer—A Comprehensive Review
- (2021) Greta Brezgyte et al. Cancers
- Chronic pancreatitis
- (2020) Georg Beyer et al. LANCET
- Targeting TAM to Tame Pancreatic Cancer
- (2020) Mitchell S. von Itzstein et al. Targeted Oncology
- Novel Circulating miRNA Signatures for Early Detection of Pancreatic Neoplasia
- (2019) Elena Vila-Navarro et al. Clinical and Translational Gastroenterology
- TAM receptors, Phosphatidylserine, inflammation, and Cancer
- (2019) Tal Burstyn-Cohen et al. Cell Communication and Signaling
- AXL receptor tyrosine kinase as a promising anti-cancer approach: functions, molecular mechanisms and clinical applications
- (2019) Chenjing Zhu et al. Molecular Cancer
- Prognostic role of carcinoembryonic antigen and carbohydrate antigen 19-9 in metastatic colorectal cancer: a BRAF-mutant subset with high CA 19-9 level and poor outcome
- (2018) Maria Thomsen et al. BRITISH JOURNAL OF CANCER
- Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk
- (2018) Carlos A. Orozco et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression
- (2018) Marie-Anne Goyette et al. Cell Reports
- Does Axl have potential as a therapeutic target in pancreatic cancer?
- (2018) Wenting Du et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Increased plasma levels of galectin-1 in pancreatic cancer: potential use as biomarker
- (2018) Neus Martinez-Bosch et al. Oncotarget
- Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis
- (2017) Julia Mayerle et al. GUT
- GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
- (2017) Zefang Tang et al. NUCLEIC ACIDS RESEARCH
- Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers
- (2017) Jungsun Kim et al. Science Translational Medicine
- The non-invasive serum biomarker soluble Axl accurately detects advanced liver fibrosis and cirrhosis
- (2017) Katharina Staufer et al. Cell Death & Disease
- Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis
- (2017) Mirko Dengler et al. Oncotarget
- IL2RG, identified as overexpressed by RNA-seq profiling of pancreatic intraepithelial neoplasia, mediates pancreatic cancer growth
- (2017) Michael Ayars et al. Oncotarget
- A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study
- (2016) Sukhwinder Kaur et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Molecular Pathways: AXL, a Membrane Receptor Mediator of Resistance to Therapy
- (2016) M. Scaltriti et al. CLINICAL CANCER RESEARCH
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- Imaging in pancreatic disease
- (2016) Julien Dimastromatteo et al. Nature Reviews Gastroenterology & Hepatology
- Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer
- (2016) Hawa Nalwoga et al. PLoS One
- Chronic pancreatitis: A diagnostic dilemma
- (2016) Sinead N Duggan et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Pancreatic Cancer Epidemiology, Detection, and Management
- (2016) Qiubo Zhang et al. Gastroenterology Research and Practice
- Monocyte and plasma expression of TAM ligand and receptor in renal failure: Links to unregulated immunity and chronic inflammation
- (2015) Iris J. Lee et al. CLINICAL IMMUNOLOGY
- PanGen-Fam: Spanish registry of hereditary pancreatic cancer
- (2015) E. Mocci et al. EUROPEAN JOURNAL OF CANCER
- Multicenter analysis of soluble Axl reveals diagnostic value for very early stage hepatocellular carcinoma
- (2015) Patrick Reichl et al. INTERNATIONAL JOURNAL OF CANCER
- Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation
- (2015) Cristina Bárcena et al. JOURNAL OF HEPATOLOGY
- Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma
- (2015) Richard A Moffitt et al. NATURE GENETICS
- Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma
- (2015) L Zhou et al. ONCOGENE
- Addressing the challenges of pancreatic cancer: Future directions for improving outcomes
- (2015) Manuel Hidalgo et al. PANCREATOLOGY
- Pancreatic Adenocarcinoma
- (2015) David P. Ryan et al. NEW ENGLAND JOURNAL OF MEDICINE
- AXL receptor tyrosine kinase is increased in patients with heart failure
- (2014) M. Batlle et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- American Pancreatic Association Practice Guidelines in Chronic Pancreatitis
- (2014) Darwin L. Conwell et al. PANCREAS
- Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET
- (2014) Erinn B. Rankin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma
- (2014) Judith Müller et al. Nature Communications
- Plasma concentrations of sAxl are associated with severe preeclampsia
- (2013) Xijing Liu et al. CLINICAL BIOCHEMISTRY
- Genetically engineered mouse models of pancreatic adenocarcinoma
- (2013) Carmen Guerra et al. Molecular Oncology
- Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy
- (2013) W Leconet et al. ONCOGENE
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- Biology of the TAM Receptors
- (2013) G. Lemke Cold Spring Harbor Perspectives in Biology
- Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
- (2012) Zhenfeng Zhang et al. NATURE GENETICS
- The role of stroma in pancreatic cancer: diagnostic and therapeutic implications
- (2012) Mert Erkan et al. Nature Reviews Gastroenterology & Hepatology
- Cutoff Finder: A Comprehensive and Straightforward Web Application Enabling Rapid Biomarker Cutoff Optimization
- (2012) Jan Budczies et al. PLoS One
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Pancreatitis-Induced Inflammation Contributes to Pancreatic Cancer by Inhibiting Oncogene-Induced Senescence
- (2011) Carmen Guerra et al. CANCER CELL
- Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
- (2011) Eric A Collisson et al. NATURE MEDICINE
- Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma
- (2010) Xianzhou Song et al. CANCER
- The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target
- (2010) Jan-Bart M. Koorstra et al. CANCER BIOLOGY & THERAPY
- Plasma concentrations of Gas6 and soluble Axl correlate with disease and predict mortality in patients with critical limb ischemia
- (2010) Carl Ekman et al. CLINICAL BIOCHEMISTRY
- Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood
- (2010) C. EKMAN et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- A scaling normalization method for differential expression analysis of RNA-seq data
- (2010) Mark D Robinson et al. GENOME BIOLOGY
- Tumor markers in pancreatic cancer: a European Group on Tumor Markers (EGTM) status report
- (2009) M. J. Duffy et al. ANNALS OF ONCOLOGY
- Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6
- (2009) S. Loges et al. BLOOD
- Plasma concentrations of growth arrest specific protein 6 and the soluble form of its tyrosine kinase receptor Axl as markers of large abdominal aortic aneurysms
- (2009) Carl Ekman et al. CLINICAL BIOCHEMISTRY
- Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival
- (2009) C. Gjerdrum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Persistent elevation of serum CA 19-9 with no evidence of malignant disease
- (2008) M. Ventrucci et al. DIGESTIVE AND LIVER DISEASE
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