N6-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cells

Harnessing liver progenitors in the treatment of liver fibrosis: a step in the right direction?

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Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma

(2020) Yongfei Yang et al.   Nature Communications

SIRT1 regulates N 6 ‐methyladenosine RNA modification in hepatocarcinogenesis by inducing RANBP2‐dependent FTO SUMOylation

(2020) Xiaoming Liu et al.   HEPATOLOGY

Hepatic fibrosis: A convergent response to liver injury that is reversible

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A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo

(2020) Panfei Xing et al.   Nature Communications

Chrysophanol attenuates hepatitis B virus X protein-induced hepatic stellate cell fibrosis by regulating endoplasmic reticulum stress and ferroptosis

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The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells

(2020) Zili Zhang et al.   Redox Biology

Chaperone-mediated autophagy is involved in the execution of ferroptosis

(2019) Zheming Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

(2019) Huilin Huang et al.   NATURE

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

(2019) Yi Niu et al.   Molecular Cancer

Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells

(2019) Feixia Wang et al.   Cell Communication and Signaling

Zfp217 mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to promote adipogenic differentiation

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RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail

(2019) Xinyao Lin et al.   Nature Communications

Clockophagy is a novel selective autophagy process favoring ferroptosis

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Oroxylin A induces apoptosis of activated hepatic stellate cells through endoplasmic reticulum stress

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m6A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7

(2019) Xinxia Wang et al.   Autophagy

RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells

(2019) Zili Zhang et al.   Autophagy

YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression

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RNA N6-methyladenosine modification in cancers: current status and perspectives

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Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α

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BECN1 is a new driver of ferroptosis

(2018) Rui Kang et al.   Autophagy

Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells

(2018) Zili Zhang et al.   Autophagy

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

(2018) Changfeng Li et al.   DEVELOPMENTAL CELL

Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells

(2018) Yan Jia et al.   Redox Biology

m6A facilitates hippocampus-dependent learning and memory through YTHDF1

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Hepatic stellate cell activation and pro-fibrogenic signals

(2017) Chandrashekhar R. Gandhi   JOURNAL OF HEPATOLOGY

Interaction between autophagy and senescence is required for dihydroartemisinin to alleviate liver fibrosis

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Autophagy regulates turnover of lipid droplets via ROS-dependent Rab25 activation in hepatic stellate cell

(2017) Zili Zhang et al.   Redox Biology

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Dihydroartemisinin counteracts fibrotic portal hypertensionviafarnesoid X receptor-dependent inhibition of hepatic stellate cell contraction

(2016) Wenxuan Xu et al.   FEBS Journal

Forkhead box A2 regulates biliary heterogeneity and senescence during cholestatic liver injury in mice‡

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Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation

(2016) Chunfeng Lu et al.   TOXICOLOGY

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

The small GTPase Rab7 as a central regulator of hepatocellular lipophagy

(2015) Barbara Schroeder et al.   HEPATOLOGY

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

(2015) Xiaofang Sun et al.   HEPATOLOGY

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

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Changes of cytokines in patients with liver cirrhosis and advanced hepatocellular carcinoma treated by sorafenib

(2013) Hidenari Nagai et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

The role of iron and reactive oxygen species in cell death

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Application of the 2010 American Association for the study of liver diseases criteria of remission to a cohort of Italian patients with autoimmune hepatitis

(2010) Luigi Muratori et al.   HEPATOLOGY

New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis

(2010) Yan Wang et al.   JOURNAL OF HEPATOLOGY