标题
RNA N6-methyladenosine modification in cancers: current status and perspectives
作者
关键词
-
出版物
CELL RESEARCH
Volume 28, Issue 5, Pages 507-517
出版商
Springer Nature
发表日期
2018-04-23
DOI
10.1038/s41422-018-0034-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m 6 A/MYC/CEBPA Signaling
- (2018) Rui Su et al. CELL
- METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m 6 A Modification
- (2018) Hengyou Weng et al. Cell Stem Cell
- Role of N 6 -methyladenosine modification in cancer
- (2018) Xiaolan Deng et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2
- (2018) Mengnuo Chen et al. HEPATOLOGY
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia
- (2017) Chau-To Kwok et al. Journal of Hematology & Oncology
- RNA m6A methylation regulates the ultraviolet-induced DNA damage response
- (2017) Yang Xiang et al. NATURE
- m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition
- (2017) Boxuan Simen Zhao et al. NATURE
- m6A modulates haematopoietic stem and progenitor cell specification
- (2017) Chunxia Zhang et al. NATURE
- Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance
- (2017) A Visvanathan et al. ONCOGENE
- m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
- (2017) Qi Cui et al. Cell Reports
- YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs
- (2017) Ian A Roundtree et al. eLife
- METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulatingN6-methyladenosine-dependent primary MicroRNA processing
- (2016) Jin-zhao Ma et al. HEPATOLOGY
- Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia
- (2016) Héléna Boutzen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Nuclear m 6 A Reader YTHDC1 Regulates mRNA Splicing
- (2016) Wen Xiao et al. MOLECULAR CELL
- The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
- (2016) Shuibin Lin et al. MOLECULAR CELL
- Reversible methylation of m6Am in the 5′ cap controls mRNA stability
- (2016) Jan Mauer et al. NATURE
- m6A RNA methylation promotes XIST-mediated transcriptional repression
- (2016) Deepak P. Patil et al. NATURE
- DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells
- (2016) Xiaotian Zhang et al. NATURE GENETICS
- Post-transcriptional gene regulation by mRNA modifications
- (2016) Boxuan Simen Zhao et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- N6-methyladenosine–encoded epitranscriptomics
- (2016) Nian Liu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA
- (2016) Chuanzhao Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- N6-methyladenosine–encoded epitranscriptomics
- (2016) Nian Liu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge
- (2016) Balraj Singh et al. PLoS One
- Presence of isocitrate dehydrogenase mutations may predict clinical response to hypomethylating agents in patients with acute myeloid leukemia
- (2015) Ashkan Emadi et al. AMERICAN JOURNAL OF HEMATOLOGY
- 5′ UTR m6A Promotes Cap-Independent Translation
- (2015) Kate D. Meyer et al. CELL
- N6-methyladenosine Modulates Messenger RNA Translation Efficiency
- (2015) Xiao Wang et al. CELL
- m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency
- (2015) Tong Chen et al. Cell Stem Cell
- N6-methyladenosine marks primary microRNAs for processing
- (2015) Claudio R. Alarcón et al. NATURE
- Dynamic m6A mRNA methylation directs translational control of heat shock response
- (2015) Jun Zhou et al. NATURE
- N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
- (2015) Nian Liu et al. NATURE
- New IDH1 mutant inhibitors for treatment of acute myeloid leukemia
- (2015) Ujunwa C Okoye-Okafor et al. Nature Chemical Biology
- FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
- (2015) Melina Claussnitzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation
- (2015) Shay Geula et al. SCIENCE
- FTO influences adipogenesis by regulating mitotic clonal expansion
- (2015) Myrte Merkestein et al. Nature Communications
- Synthesis of a FTO Inhibitor with Anticonvulsant Activity
- (2014) Guanqun Zheng et al. ACS Chemical Neuroscience
- IDH1 Overexpression Induced Chemotherapy Resistance and IDH1 Mutation Enhanced Chemotherapy Sensitivity in Glioma Cells in Vitro and in Vivo
- (2014) Ju-Bo Wang et al. Asian Pacific Journal of Cancer Prevention
- FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis
- (2014) Xu Zhao et al. CELL RESEARCH
- Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
- (2014) Xiao-Li Ping et al. CELL RESEARCH
- WTAP is a novel oncogenic protein in acute myeloid leukemia
- (2014) H Bansal et al. LEUKEMIA
- Single nucleotide polymorphisms of the FTO gene and cancer risk: an overview
- (2014) Marta Elena Hernández-Caballero et al. MOLECULAR BIOLOGY REPORTS
- Obesity-associated variants within FTO form long-range functional connections with IRX3
- (2014) Scott Smemo et al. NATURE
- N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
- (2014) Yang Wang et al. NATURE CELL BIOLOGY
- Gene expression regulation mediated through reversible m6A RNA methylation
- (2014) Ye Fu et al. NATURE REVIEWS GENETICS
- Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5
- (2014) Yue Huang et al. NUCLEIC ACIDS RESEARCH
- Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
- (2014) Schraga Schwartz et al. Cell Reports
- AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model
- (2013) M. Wunderlich et al. BLOOD
- A link between FTO, ghrelin, and impaired brain food-cue responsivity
- (2013) Efthimia Karra et al. JOURNAL OF CLINICAL INVESTIGATION
- N6-methyladenosine-dependent regulation of messenger RNA stability
- (2013) Xiao Wang et al. NATURE
- A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
- (2013) Jianzhao Liu et al. Nature Chemical Biology
- (R)-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
- (2013) J.-A. Losman et al. SCIENCE
- An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
- (2013) D. Rohle et al. SCIENCE
- Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation
- (2013) F. Wang et al. SCIENCE
- Increased incidence of non-Hodgkin lymphoma, leukemia, and myeloma in patients with diabetes mellitus type 2: a meta-analysis of observational studies
- (2012) J. J. Castillo et al. BLOOD
- Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
- (2012) Kate D. Meyer et al. CELL
- Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?
- (2012) Jessica L. Bell et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Development of Cell-Active N6-Methyladenosine RNA Demethylase FTO Inhibitor
- (2012) Baoen Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
- (2012) Guanqun Zheng et al. MOLECULAR CELL
- IDH mutation impairs histone demethylation and results in a block to cell differentiation
- (2012) Chao Lu et al. NATURE
- FTO genotype is associated with phenotypic variability of body mass index
- (2012) Jian Yang et al. NATURE
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia
- (2012) Jay P. Patel et al. NEW ENGLAND JOURNAL OF MEDICINE
- MODOMICS: a database of RNA modification pathways—2013 update
- (2012) Magdalena A. Machnicka et al. NUCLEIC ACIDS RESEARCH
- Reversible RNA adenosine methylation in biological regulation
- (2012) Guifang Jia et al. TRENDS IN GENETICS
- Association between FTO gene polymorphism and cancer risk: evidence from 16,277 cases and 31,153 controls
- (2012) Guiqiong Li et al. TUMOR BIOLOGY
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
- (2011) J. Zuber et al. GENES & DEVELOPMENT
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
- The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels
- (2010) Tea Berulava et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis
- (2010) Shenghao Jin et al. JOURNAL OF CLINICAL INVESTIGATION
- The prognostic impact and stability of Isocitrate dehydrogenase 2 mutation in adult patients with acute myeloid leukemia
- (2010) W-C Chou et al. LEUKEMIA
- Grand Challenge Commentary: RNA epigenetics?
- (2010) Chuan He Nature Chemical Biology
- Overexpression of Fto leads to increased food intake and results in obesity
- (2010) Chris Church et al. NATURE GENETICS
- DNMT3AMutations in Acute Myeloid Leukemia
- (2010) Timothy J. Ley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inactivation of the Fto gene protects from obesity
- (2009) Julia Fischer et al. NATURE
- Mutation inTET2in Myeloid Cancers
- (2009) François Delhommeau et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1
- (2009) S. Zhao et al. SCIENCE
- Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation
- (2008) M. Wall et al. BLOOD
- Overweight, obesity and risk of haematological malignancies: A cohort study of Swedish and Finnish twins
- (2008) Karin C. Söderberg et al. EUROPEAN JOURNAL OF CANCER
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now