Exploration of BAY 11-7082 as a Potential Antibiotic

Repurposing Kinase Inhibitor Bay 11-7085 to Combat Staphylococcus aureus and Candida albicans Biofilms

(2021) Iliana E. Escobar et al.   Frontiers in Pharmacology

The Science of Antibiotic Discovery

(2020) Kim Lewis   CELL

Statins Promote IL-1β-Dependent Adipocyte Insulin Resistance via Lower Prenylation not Cholesterol

(2019) Brandyn D. Henriksbo et al.   DIABETES

Thiostrepton hijacks pyoverdine receptors to inhibit growth of Pseudomonas aeruginosa

(2019) Michael R.M. Ranieri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanisms of biofilm stimulation by subinhibitory concentrations of antimicrobials

(2018) Michael RM Ranieri et al.   CURRENT OPINION IN MICROBIOLOGY

Extensive impact of non-antibiotic drugs on human gut bacteria

(2018) Lisa Maier et al.   NATURE

Natural-Product Antibiotics: Cues for Modulating Bacterial Biofilm Formation

(2017) Loni Townsley et al.   TRENDS IN MICROBIOLOGY

Progress in the Fight Against Multidrug-Resistant Bacteria? A Review of U.S. Food and Drug Administration–Approved Antibiotics, 2010–2015

(2016) Dalia Deak et al.   ANNALS OF INTERNAL MEDICINE

Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions

(2016) Paul A. Jackson et al.   JOURNAL OF MEDICINAL CHEMISTRY

High Throughput Screen for Escherichia coli Twin Arginine Translocation (Tat) Inhibitors

(2016) Umesh K. Bageshwar et al.   PLoS One

Antibacterial properties of 3-(phenylsulfonyl)-2-pyrazinecarbonitrile

(2015) Rajmohan Rajamuthiah et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies

(2015) Renato A. Bauer   DRUG DISCOVERY TODAY

BAY 11-7082 ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated oxidative stress and renal inflammation via NF-κB pathway

(2015) Sambasiva Rao Kolati et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Fluvastatin Causes NLRP3 Inflammasome-Mediated Adipose Insulin Resistance

(2014) Brandyn D. Henriksbo et al.   DIABETES

Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis

(2014) Shyam Krishnan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Changes to Its Peptidoglycan-Remodeling Enzyme Repertoire Modulate β-Lactam Resistance in Pseudomonas aeruginosa

(2013) Joseph F. Cavallari et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Collapsing the Proton Motive Force to Identify Synergistic Combinations against Staphylococcus aureus

(2013) Maya A. Farha et al.   CHEMISTRY & BIOLOGY

The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases

(2013) Navasona Krishnan et al.   FEBS Journal

Drug repurposing: mining protozoan proteomes for targets of known bioactive compounds

(2013) Adam Sateriale et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

A Genetic Resource for Rapid and Comprehensive Phenotype Screening of Nonessential Staphylococcus aureus Genes

(2013) P. D. Fey et al.   mBio

Identification and Evaluation of Twin-Arginine Translocase Inhibitors

(2012) Michael L. Vasil et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Protein tyrosine phosphatase structure-function relationships in regulation and pathogenesis

(2012) Frank Böhmer et al.   FEBS Journal

BAY 11-7082 Is a Broad-Spectrum Inhibitor with Anti-Inflammatory Activity against Multiple Targets

(2012) Jaehwi Lee et al.   MEDIATORS OF INFLAMMATION

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

(2012) Iana M Serafimova et al.   Nature Chemical Biology

Tracking a Hospital Outbreak of Carbapenem-Resistant Klebsiella pneumoniae with Whole-Genome Sequencing

(2012) E. S. Snitkin et al.   Science Translational Medicine

Small-Molecule Modulators of Listeria monocytogenes Biofilm Development

(2011) Uyen T. Nguyen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Palmitoyl-dl-Carnitine is a Multitarget Inhibitor of Pseudomonas aeruginosa Biofilm Development

(2011) Iwona B. Wenderska et al.   CHEMBIOCHEM

Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children

(2011) Catherine Liu et al.   CLINICAL INFECTIOUS DISEASES

Challenges of Antibacterial Discovery

(2011) L. L. Silver   CLINICAL MICROBIOLOGY REVIEWS

The resurgence of covalent drugs

(2011) Juswinder Singh et al.   NATURE REVIEWS DRUG DISCOVERY

Depolarization, Bacterial Membrane Composition, and the Antimicrobial Action of Ceragenins

(2010) R. F. Epand et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Resistance or decreased susceptibility to glycopeptides, daptomycin, and linezolid in methicillin-resistant Staphylococcus aureus

(2010) Esteban Nannini et al.   CURRENT OPINION IN PHARMACOLOGY

Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome

(2010) Christine Juliana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the Twin-Arginine Translocation Pathway in Staphylococcus

(2009) L. Biswas et al.   JOURNAL OF BACTERIOLOGY

Covalent Modifiers: An Orthogonal Approach to Drug Design

(2009) Michele H. Potashman et al.   JOURNAL OF MEDICINAL CHEMISTRY

BAY 11-7082 induces cell death through NF-κB-independent mechanisms in the Ewing’s sarcoma family of tumours

(2008) Danielle E. White et al.   CANCER LETTERS

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Federal Funding for the Study of Antimicrobial Resistance in Nosocomial Pathogens: No ESKAPE

(2008) Louis B. Rice   JOURNAL OF INFECTIOUS DISEASES