Pathogen clonal expansion underlies multiorgan dissemination and organ-specific outcomes during murine systemic infection

RESTAMP - Rate estimates by sequence-tag analysis of microbial populations

(2021) Anel Mahmutovic et al.   Computational and Structural Biotechnology Journal

Pathogenesis of Gram-Negative Bacteremia

(2021) Caitlyn L. Holmes et al.   CLINICAL MICROBIOLOGY REVIEWS

Refined Quantification of Infection Bottlenecks and Pathogen Dissemination with STAMPR

(2021) Karthik Hullahalli et al.   mSystems

Systemic infection facilitates transmission of Pseudomonas aeruginosa in mice

(2020) Kelly E. R. Bachta et al.   Nature Communications

Chromosomal barcoding of E. coli populations reveals lineage diversity dynamics at high resolution

(2020) Weronika Jasinska et al.   Nature Ecology & Evolution

Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection

(2020) Matthew K. Siggins et al.   Nature Communications

Exploration of Bacterial Bottlenecks and Streptococcus pneumoniae Pathogenesis by CRISPRi-Seq

(2020) Xue Liu et al.   Cell Host & Microbe

Unsupervised Learning Approach for Comparing Multiple Transposon Insertion Sequencing Studies

(2019) Troy P. Hubbard et al.   mSphere

Twin arginine translocation, ammonia incorporation, and polyamine biosynthesis are crucial for Proteus mirabilis fitness during bloodstream infection

(2019) Chelsie E. Armbruster et al.   PLoS Pathogens

Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features

(2019) Joyce E. Karlinsey et al.   Cell Host & Microbe

Peritoneal GATA6+ macrophages function as a portal for Staphylococcus aureus dissemination

(2019) Selina K. Jorch et al.   JOURNAL OF CLINICAL INVESTIGATION

Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization

(2019) Alyson R. Warr et al.   PLoS Pathogens

Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression

(2019) Siddharth Subramaniyam et al.   BMC BIOINFORMATICS

Host resistance factor SLC11A1 restricts Salmonella growth through magnesium deprivation

(2019) Olivier Cunrath et al.   SCIENCE

A multihost bacterial pathogen overcomes continuous population bottlenecks to adapt to new host species

(2019) Rodrigo Bacigalupe et al.   Science Advances

Genome-Wide Identification by Transposon Insertion Sequencing of Escherichia coli K1 Genes Essential for In Vitro Growth, Gastrointestinal Colonizing Capacity, and Survival in Serum

(2018) Alex J. McCarthy et al.   JOURNAL OF BACTERIOLOGY

The lytic transglycosylase MltB connects membrane homeostasis and in vivo fitness of Acinetobacter baumannii

(2018) Sébastien Crépin et al.   MOLECULAR MICROBIOLOGY

A live vaccine rapidly protects against cholera in an infant rabbit model

(2018) Troy P. Hubbard et al.   Science Translational Medicine

Staphylococcus aureus infection dynamics

(2018) Eric J. G. Pollitt et al.   PLoS Pathogens

Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia

(2018) Giuseppe Ercoli et al.   Nature Microbiology

Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen

(2018) Karina K. Sanchez et al.   CELL

Citrobacter freundii fitness during bloodstream infection

(2018) Mark T. Anderson et al.   Scientific Reports

Deciphering the landscape of host barriers toListeria monocytogenesinfection

(2017) Ting Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of removing Kupffer cells on nanoparticle tumor delivery

(2017) Anthony J. Tavares et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capsule Production and Glucose Metabolism Dictate Fitness during Serratia marcescens Bacteremia

(2017) Mark T. Anderson et al.   mBio

Stochastic variation in the initial phase of bacterial infection predicts the probability of survival in D. melanogaster

(2017) David Duneau et al.   eLife

Hemolysin of uropathogenic Escherichia coli: A cloak or a dagger?

(2016) Laura C. Ristow et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Fast-Track Clearance of Bacteria from the Liver

(2016) Cristina Llorente et al.   Cell Host & Microbe

Genetic analysis ofVibrio parahaemolyticusintestinal colonization

(2016) Troy P. Hubbard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FtsEX acts on FtsA to regulate divisome assembly and activity

(2016) Shishen Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multigene Editing in the Escherichia coli Genome via the CRISPR-Cas9 System

(2015) Yu Jiang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Extra-intestinal pathogenic Escherichia coli (ExPEC): Disease, carriage and clones

(2015) Adam P. Dale et al.   JOURNAL OF INFECTION

Sequence tag–based analysis of microbial population dynamics

(2015) Sören Abel et al.   NATURE METHODS

dsdA Does Not Affect Colonization of the Murine Urinary Tract by Escherichia coli CFT073

(2015) Andrew J. Hryckowian et al.   PLoS One

Analysis of Bottlenecks in Experimental Models of Infection

(2015) Sören Abel et al.   PLoS Pathogens

Escherichia coli α-Hemolysin Counteracts the Anti-Virulence Innate Immune Response Triggered by the Rho GTPase Activating Toxin CNF1 during Bacteremia

(2015) Mamady Diabate et al.   PLoS Pathogens

Acinetobacter baumannii Genes Required for Bacterial Survival during Bloodstream Infection

(2015) Sargurunathan Subashchandrabose et al.   mSphere

Host Glycan Sugar-Specific Pathways in Streptococcus pneumonia: Galactose as a Key Sugar in Colonisation and Infection

(2015) Laura Paixão et al.   PLoS One

Beyond genome sequencing: Lineage tracking with barcodes to study the dynamics of evolution, infection, and cancer

(2014) Jamie R. Blundell et al.   GENOMICS

Superantigens Subvert the Neutrophil Response To Promote Abscess Formation and Enhance Staphylococcus aureus SurvivalIn Vivo

(2014) Stacey X. Xu et al.   INFECTION AND IMMUNITY

Genome-Wide Identification of Acinetobacter baumannii Genes Necessary for Persistence in the Lung

(2014) N. Wang et al.   mBio

ARTIST: High-Resolution Genome-Wide Assessment of Fitness Using Transposon-Insertion Sequencing

(2014) Justin R. Pritchard et al.   PLoS Genetics

The Role of Host and Microbial Factors in the Pathogenesis of Pneumococcal Bacteraemia Arising from a Single Bacterial Cell Bottleneck

(2014) Alice Gerlini et al.   PLoS Pathogens

Immune surveillance by the liver

(2013) Craig N Jenne et al.   NATURE IMMUNOLOGY

RpoS Contributes to Phagocyte Oxidase-Mediated Stress Resistance during Urinary Tract Infection by Escherichia coli CFT073

(2013) A. J. Hryckowian et al.   mBio

The complex pathogenesis of bacteremia

(2013) Eirini Christaki et al.   Virulence

Genome-Wide Detection of Fitness Genes in Uropathogenic Escherichia coli during Systemic Infection

(2013) Sargurunathan Subashchandrabose et al.   PLoS Pathogens

An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring

(2011) D. C. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preventing Staphylococcus aureus Sepsis through the Inhibition of Its Agglutination in Blood

(2011) Molly McAdow et al.   PLoS Pathogens

Silent Mischief: Bacteriophage Mu Insertions Contaminate Products of Escherichia coli Random Mutagenesis Performed Using Suicidal Transposon Delivery Plasmids Mobilized by Broad-Host-Range RP4 Conjugative Machinery

(2010) L. Ferrieres et al.   JOURNAL OF BACTERIOLOGY

Dissemination and Systemic Colonization of Uropathogenic Escherichia coli in a Murine Model of Bacteremia

(2010) S. N. Smith et al.   mBio

A Population-Based Study of Pyogenic Liver Abscesses in the United States: Incidence, Mortality and Temporal Trends

(2009) Liisa Meddings et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues

(2009) Alice G. Cheng et al.   FASEB JOURNAL

An ABC transport system that maintains lipid asymmetry in the Gram-negative outer membrane

(2009) J. C. Malinverni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modelling within-Host Spatiotemporal Dynamics of Invasive Bacterial Disease

(2008) Andrew J Grant et al.   PLOS BIOLOGY