标题
Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1
作者
关键词
-
出版物
eLife
Volume 10, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2021-12-06
DOI
10.7554/elife.72823
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration
- (2021) Matthew D. Figley et al. NEURON
- Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing
- (2021) Weixi Gu et al. Acta Crystallographica Section F-Structural Biology Communications
- Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection
- (2021) Yo Sasaki et al. EXPERIMENTAL NEUROLOGY
- Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss
- (2021) Tong Wu et al. Cell Reports
- Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders
- (2021) Jonathan Gilley et al. eLife
- cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons
- (2020) Yo Sasaki et al. EXPERIMENTAL NEUROLOGY
- Programmed axon degeneration: from mouse to mechanism to medicine
- (2020) Michael P. Coleman et al. NATURE REVIEWS NEUROSCIENCE
- Structural and Mechanistic Regulation of the Pro-degenerative NAD Hydrolase SARM1
- (2020) Matthew Bratkowski et al. Cell Reports
- The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative Sarm1
- (2020) Yuefeng Jiang et al. NATURE
- Gene therapy targeting SARM1 blocks pathological axon degeneration in mice
- (2019) Stefanie Geisler et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence
- (2019) Marshall Lukacs et al. EXPERIMENTAL NEUROLOGY
- Homozygous NMNAT2 mutation in sisters with polyneuropathy and erythromelalgia
- (2019) Peter Huppke et al. EXPERIMENTAL NEUROLOGY
- Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration
- (2019) Andrea Loreto et al. NEUROBIOLOGY OF DISEASE
- Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury
- (2018) Kimberly A. Fernandes et al. EXPERIMENTAL EYE RESEARCH
- Neuroprotection of retinal ganglion cells by a novel gene therapy construct that achieves sustained enhancement of brain-derived neurotrophic factor/tropomyosin-related kinase receptor-B signaling
- (2018) Andrew Osborne et al. Cell Death & Disease
- The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD + Cleavage Activity that Promotes Pathological Axonal Degeneration
- (2017) Kow Essuman et al. NEURON
- PDBsum: Structural summaries of PDB entries
- (2017) Roman A. Laskowski et al. PROTEIN SCIENCE
- Sarm1 Deletion, but Not Wld S , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy
- (2017) Jonathan Gilley et al. Cell Reports
- Pellagra Secondary to Medication and Alcoholism
- (2016) Rongrong Li et al. NUTRITION IN CLINICAL PRACTICE
- NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion
- (2016) Yo Sasaki et al. eLife
- SARM1 activation triggers axon degeneration locally via NAD+ destruction
- (2015) J. Gerdts et al. SCIENCE
- Absence of SARM1 Rescues Development and Survival of NMNAT2-Deficient Axons
- (2015) Jonathan Gilley et al. Cell Reports
- Wallerian Degeneration Is Executed by an NMN-SARM1-Dependent Late Ca 2+ Influx but Only Modestly Influenced by Mitochondria
- (2015) Andrea Loreto et al. Cell Reports
- A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration
- (2014) M Di Stefano et al. CELL DEATH AND DIFFERENTIATION
- Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the NAD+biosynthetic machinery in mammalian cells
- (2014) Federica Zamporlini et al. FEBS Journal
- Metabolic Profiling of Alternative NAD Biosynthetic Routes in Mouse Tissues
- (2014) Valerio Mori et al. PLoS One
- How good are my data and what is the resolution?
- (2013) Philip R. Evans et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Sarm1-Mediated Axon Degeneration Requires Both SAM and TIR Interactions
- (2013) J. Gerdts et al. JOURNAL OF NEUROSCIENCE
- Simultaneous Single-Sample Determination of NMNAT Isozyme Activities in Mouse Tissues
- (2013) Giuseppe Orsomando et al. PLoS One
- Towards automated crystallographic structure refinement withphenix.refine
- (2012) Pavel V. Afonine et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway
- (2012) J. M. Osterloh et al. SCIENCE
- Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology
- (2011) Chiung-Ya Chen et al. JOURNAL OF CELL BIOLOGY
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Endogenous Nmnat2 Is an Essential Survival Factor for Maintenance of Healthy Axons
- (2010) Jonathan Gilley et al. PLOS BIOLOGY
- Nicotinamide Mononucleotide Adenylyl Transferase-Mediated Axonal Protection Requires Enzymatic Activity But Not Increased Levels of Neuronal Nicotinamide Adenine Dinucleotide
- (2009) Y. Sasaki et al. JOURNAL OF NEUROSCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now