Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion

Candidalysin triggers epithelial cellular stresses that induce necrotic death

(2021) Mariana Blagojevic et al.   CELLULAR MICROBIOLOGY

A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis

(2021) Junyan Liu et al.   PLoS Pathogens

The gut, the bad and the harmless: Candida albicans as a commensal and opportunistic pathogen in the intestine

(2020) Carol A Kumamoto et al.   CURRENT OPINION IN MICROBIOLOGY

Oral epithelial IL-22/STAT3 signaling licenses IL-17–mediated immunity to oral mucosal candidiasis

(2020) Felix E. Y. Aggor et al.   Science Immunology

Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection

(2020) Johannes Westman et al.   Cell Host & Microbe

Integrity under stress: Host membrane remodelling and damage by fungal pathogens

(2019) Johannes Westman et al.   CELLULAR MICROBIOLOGY

Candida albicans Morphogenesis Programs Control the Balance between Gut Commensalism and Invasive Infection

(2019) Jessica N. Witchley et al.   Cell Host & Microbe

Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor

(2019) Jemima Ho et al.   Nature Communications

Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection

(2019) Marc Swidergall et al.   JOURNAL OF INFECTIOUS DISEASES

Candidalysin: discovery and function in Candida albicans infections

(2019) Julian R Naglik et al.   CURRENT OPINION IN MICROBIOLOGY

Candida albicans -Induced Epithelial Damage Mediates Translocation through Intestinal Barriers

(2018) Stefanie Allert et al.   mBio

Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes

(2018) Michelle E Maxson et al.   eLife

Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization

(2018) Johannes Westman et al.   mBio

The intraspecies diversity of C. albicans triggers qualitatively and temporally distinct host responses that determine the balance between commensalism and pathogenicity

(2017) F A Schönherr et al.   Mucosal Immunology

Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack

(2016) Heidi Wolfmeier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Candidalysin is a fungal peptide toxin critical for mucosal infection

(2016) David L. Moyes et al.   NATURE

Candida albicans-epithelial interactions and pathogenicity mechanisms: scratching the surface

(2015) David L Moyes et al.   Virulence

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

(2014) Gerald R.V. Hammond et al.   JOURNAL OF CELL BIOLOGY

Temporal and spatial organization of ESCRT protein recruitment during HIV-1 budding

(2014) M. Bleck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ESCRT Machinery Is Required for Plasma Membrane Repair

(2014) A. J. Jimenez et al.   SCIENCE

Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair

(2014) Luana L. Scheffer et al.   Nature Communications

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Analysis of cytotoxicity of melittin on adherent culture of human endothelial cells reveals advantage of fluorescence microscopy over flow cytometry and haemocytometer assay

(2013) Katarina Černe et al.   PROTOPLASMA

Candida albicanspathogenicity mechanisms

(2013) François L. Mayer et al.   Virulence

Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida albicans in Macrophages

(2013) Karin Strijbis et al.   PLoS Pathogens

Cell-Permeable Gomesin Peptide Promotes Cell Death by Intracellular Ca2+ Overload

(2012) Edgar J. Paredes-Gamero et al.   MOLECULAR PHARMACEUTICS

Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane

(2011) P. A. Keyel et al.   JOURNAL OF CELL SCIENCE

Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling

(2011) Michal Bohdanowicz et al.   MOLECULAR BIOLOGY OF THE CELL

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages

(2011) A. Esteban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments

(2011) J. Guizetti et al.   SCIENCE

A Biphasic Innate Immune MAPK Response Discriminates between the Yeast and Hyphal Forms of Candida albicans in Epithelial Cells

(2010) David L. Moyes et al.   Cell Host & Microbe

Intracellular Ca2+ operates a switch between repair and lysis of streptolysin O-perforated cells

(2009) E B Babiychuk et al.   CELL DEATH AND DIFFERENTIATION

Cellular interactions ofCandida albicanswith human oral epithelial cells and enterocytes

(2009) Frederic Dalle et al.   CELLULAR MICROBIOLOGY

Property Differences among the Four MajorCandida albicansStrain Clades

(2009) Donna M. MacCallum et al.   EUKARYOTIC CELL

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE