Development of a simple and miniaturized sandwich-like fluorescence polarization assay for rapid screening of SARS-CoV-2 main protease inhibitors

Development of a Cell-Based Luciferase Complementation Assay for Identification of SARS-CoV-2 3CLpro Inhibitors

(2021) Jonathan M. O. Rawson et al.   Viruses-Basel

mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants

(2021) Zijun Wang et al.   NATURE

Dipyridamole, chloroquine, montelukast sodium, candesartan, oxytetracycline, and atazanavir are not SARS-CoV-2 main protease inhibitors

(2021) Chunlong Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model

(2021) Jingxin Qiao et al.   SCIENCE

Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases

(2021) Zinuo Chen et al.   Cell and Bioscience

Fluorescence polarization system for rapid COVID-19 diagnosis

(2021) Chang Yeol Lee et al.   BIOSENSORS & BIOELECTRONICS

Dieckol and Its Derivatives as Potential Inhibitors of SARS-CoV-2 Spike Protein (UK Strain: VUI 202012/01): A Computational Study

(2021) Mohammad Aatif et al.   Marine Drugs

Discovery of chebulagic acid and punicalagin as novel allosteric inhibitors of SARS-CoV-2 3CLpro

(2021) Ruikun Du et al.   ANTIVIRAL RESEARCH

An all-out assault on SARS-CoV-2 replication

(2021) Ronald T. Hay   BIOCHEMICAL JOURNAL

Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

(2021) Jamie Lopez Bernal et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2: from its discovery to genome structure, transcription, and replication

(2021) Ayslan Castro Brant et al.   Cell and Bioscience

Dieckol: a brown algal phlorotannin with biological potential

(2021) Durairaj Karthick Rajan et al.   BIOMEDICINE & PHARMACOTHERAPY

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

(2020) Zhenming Jin et al.   NATURE

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

(2020) Linlin Zhang et al.   SCIENCE

Targeting the Dimerization of the Main Protease of Coronaviruses: A Potential Broad-Spectrum Therapeutic Strategy

(2020) Bhupesh Goyal et al.   ACS Combinatorial Science

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

(2020) Bette Korber et al.   CELL

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

(2020) Laura Riva et al.   NATURE

Development of a Fluorescence-Based, High-Throughput SARS-CoV-2 3CLpro Reporter Assay

(2020) Heather M. Froggatt et al.   JOURNAL OF VIROLOGY

Potential roles of medicinal plants for the treatment of viral diseases focusing on COVID ‐19: A review

(2020) Bikash Adhikari et al.   PHYTOTHERAPY RESEARCH

Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

(2020) Zhe Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

(2020) Lifeng Fu et al.   Nature Communications

Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

(2020) Wayne Vuong et al.   Nature Communications

Covid-19: Remdesivir has little or no impact on survival, WHO trial shows

(2020) Owen Dyer   BMJ-British Medical Journal

Optimizations of a novel fluorescence polarization-based high-throughput screening assay for β-catenin/LEF1 interaction inhibitors

(2020) Yunyu Chen et al.   ANALYTICAL BIOCHEMISTRY

Covid-19: What now for remdesivir?

(2020) Jeremy Hsu   BMJ-British Medical Journal

ACE2: the molecular doorway to SARS-CoV-2

(2020) Miriam Marlene Medina-Enríquez et al.   Cell and Bioscience

Sensitive Rapid Fluorescence Polarization Immunoassay for Free Mycophenolic Acid Determination in Human Serum and Plasma

(2018) Bettina Glahn-Martínez et al.   ANALYTICAL CHEMISTRY

Plant natural product plumbagin presents potent inhibitory effect on human cytochrome P450 2J2 enzyme

(2018) Jian Lu et al.   PHYTOMEDICINE

Anti-HIV-1 activity of phlorotannin derivative 8,4‴-dieckol from Korean brown algaEcklonia cava

(2014) Fatih Karadeniz et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Dieckol, a SARS-CoV 3CLpro inhibitor, isolated from the edible brown algae Ecklonia cava

(2013) Ji-Young Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Potential pharmacological applications of polyphenolic derivatives from marine brown algae

(2011) Noel Vinay Thomas et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Influenza Virus Neuraminidase Inhibitory Activity of Phlorotannins from the Edible Brown AlgaEcklonia cava

(2011) Young Bae Ryu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY