Drug repurposing improves disease targeting 11-fold and can be augmented by network module targeting, applied to COVID-19
出版年份 2021 全文链接
标题
Drug repurposing improves disease targeting 11-fold and can be augmented by network module targeting, applied to COVID-19
作者
关键词
-
出版物
Scientific Reports
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-10-19
DOI
10.1038/s41598-021-99721-y
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Network medicine framework for identifying drug-repurposing opportunities for COVID-19
- (2021) Deisy Morselli Gysi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multi-arm Trial of Inflammatory Signal Inhibitors (MATIS) for hospitalised patients with mild or moderate COVID-19 pneumonia: a structured summary of a study protocol for a randomised controlled trial
- (2021) Nikhil Vergis et al. Trials
- A network pharmacology approach to explore the potential targets underlying the effect of sinomenine on rheumatoid arthritis
- (2020) Xiang Guo et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- Remdesivir for the Treatment of Covid-19 — Preliminary Report
- (2020) John H. Beigel et al. NEW ENGLAND JOURNAL OF MEDICINE
- Elevated MUC1 and MUC5AC mucin protein levels in airway mucus of critical ill COVID‐19 Patients
- (2020) Wenju Lu et al. JOURNAL OF MEDICAL VIROLOGY
- Fostamatinib Inhibits Neutrophils Extracellular Traps Induced by COVID-19 Patient Plasma: A Potential Therapeutic
- (2020) Jeffrey R Strich et al. JOURNAL OF INFECTIOUS DISEASES
- Drug repurposing for antimicrobial discovery
- (2019) Maya A. Farha et al. Nature Microbiology
- Assessment of network module identification across complex diseases
- (2019) Sarvenaz Choobdar et al. NATURE METHODS
- To Bind or Not to Bind: Unravelling GPCR Polypharmacology
- (2018) Patrick M. Sexton et al. CELL
- Etanercept for the treatment of rheumatoid arthritis
- (2018) Sizheng Zhao et al. Immunotherapy
- Network-Based Disease Module Discovery by a Novel Seed Connector Algorithm with Pathobiological Implications
- (2018) Rui-Sheng Wang et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural absorption by barbule microstructures of super black bird of paradise feathers
- (2018) Dakota E. McCoy et al. Nature Communications
- The Comparative Toxicogenomics Database: update 2019
- (2018) Allan Peter Davis et al. NUCLEIC ACIDS RESEARCH
- Drug repurposing: progress, challenges and recommendations
- (2018) Sudeep Pushpakom et al. NATURE REVIEWS DRUG DISCOVERY
- FunCoup 4: new species, data, and visualization
- (2017) Christoph Ogris et al. NUCLEIC ACIDS RESEARCH
- DrugBank 5.0: a major update to the DrugBank database for 2018
- (2017) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
- (2017) Michiru Nishita et al. Scientific Reports
- Atezolizumab: A PD-L1–Blocking Antibody for Bladder Cancer
- (2016) Brant A. Inman et al. CLINICAL CANCER RESEARCH
- Network-based in silico drug efficacy screening
- (2016) Emre Guney et al. Nature Communications
- Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing
- (2016) Janet Piñero et al. Scientific Reports
- Tissue Specificity of Human Disease Module
- (2016) Maksim Kitsak et al. Scientific Reports
- A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma
- (2015) Amitabh Sharma et al. HUMAN MOLECULAR GENETICS
- Uncovering disease-disease relationships through the incomplete interactome
- (2015) J. Menche et al. SCIENCE
- A DIseAse MOdule Detection (DIAMOnD) Algorithm Derived from a Systematic Analysis of Connectivity Patterns of Disease Proteins in the Human Interactome
- (2015) Susan Dina Ghiassian et al. PLoS Computational Biology
- MaxLink: network-based prioritization of genes tightly linked to a disease seed set
- (2014) Dimitri Guala et al. BIOINFORMATICS
- InParanoid 8: orthology analysis between 273 proteomes, mostly eukaryotic
- (2014) Erik L.L. Sonnhammer et al. NUCLEIC ACIDS RESEARCH
- Getting Syk: spleen tyrosine kinase as a therapeutic target
- (2014) Robert L. Geahlen TRENDS IN PHARMACOLOGICAL SCIENCES
- Shifting from the single to the multitarget paradigm in drug discovery
- (2013) José L. Medina-Franco et al. DRUG DISCOVERY TODAY
- The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases
- (2013) Sandra Orchard et al. NUCLEIC ACIDS RESEARCH
- Signaling Network Assessment of Mutations and Copy Number Variations Predict Breast Cancer Subtype-Specific Drug Targets
- (2013) Naif Zaman et al. Cell Reports
- Principles of early drug discovery
- (2010) JP Hughes et al. BRITISH JOURNAL OF PHARMACOLOGY
- The map equation
- (2010) M. Rosvall et al. European Physical Journal-Special Topics
- Global networks of functional coupling in eukaryotes from comprehensive data integration
- (2009) A. Alexeyenko et al. GENOME RESEARCH
- Molecular networks and system-level properties
- (2009) Lilia Alberghina et al. JOURNAL OF BIOTECHNOLOGY
- Molecular networks as sensors and drivers of common human diseases
- (2009) Eric E. Schadt NATURE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started