Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation
出版年份 2021 全文链接
标题
Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation
作者
关键词
-
出版物
Nature Communications
Volume 12, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-12-15
DOI
10.1038/s41467-021-27433-y
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Drug startups coalesce around condensates
- (2021) Elie Dolgin NATURE BIOTECHNOLOGY
- Ligand effects on phase separation of multivalent macromolecules
- (2021) Kiersten M. Ruff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulating α-Synuclein Liquid–Liquid Phase Separation
- (2021) Ajay Singh Sawner et al. BIOCHEMISTRY
- Microfluidic Shrinking Droplet Concentrator for Analyte Detection and Phase Separation of Protein Solutions
- (2020) Marie R. G. Kopp et al. ANALYTICAL CHEMISTRY
- Composition-dependent thermodynamics of intracellular phase separation
- (2020) Joshua A. Riback et al. NATURE
- Liquid–liquid phase separation of type II diabetes-associated IAPP initiates hydrogelation and aggregation
- (2020) Lior Pytowski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In-Solution IgG Titer Determination in Fermentation Broth Using Affibodies and Flow-Induced Dispersion Analysis
- (2020) Morten E. Pedersen et al. ACS Omega
- Analysis of biomolecular condensates and protein phase separation with microfluidic technology
- (2020) Miriam Linsenmeier et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- α-Synuclein aggregation nucleates through liquid–liquid phase separation
- (2020) Soumik Ray et al. Nature Chemistry
- De novo engineering of intracellular condensates using artificial disordered proteins
- (2020) Michael Dzuricky et al. Nature Chemistry
- Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
- (2020) Yi Shen et al. Nature Nanotechnology
- Phase transition of RNA−protein complexes into ordered hollow condensates
- (2020) Ibraheem Alshareedah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Partitioning of cancer therapeutics in nuclear condensates
- (2020) Isaac A. Klein et al. SCIENCE
- Phase Separation—A Physical Mechanism for Organizing Information and Biochemical Reactions
- (2020) Rohit V. Pappu DEVELOPMENTAL CELL
- Predictable phase-separated proteins
- (2020) Soumik Ray et al. Nature Chemistry
- Biomolecular condensates in photosynthesis and metabolism
- (2020) Tobias Wunder et al. CURRENT OPINION IN PLANT BIOLOGY
- Widespread occurrence of the droplet state of proteins in the human proteome
- (2020) Maarten Hardenberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of liquid-liquid phase separation in aggregation of the TDP-43 low complexity domain
- (2019) W. Michael Babinchak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
- (2019) Simon Alberti et al. CELL
- Heterochromatin drives compartmentalization of inverted and conventional nuclei
- (2019) Martin Falk et al. NATURE
- N-Terminal Acetylation Affects α-Synuclein Fibril Polymorphism
- (2019) Matthew D. Watson et al. BIOCHEMISTRY
- Functional Implications of Intracellular Phase Transitions
- (2018) Alex S. Holehouse et al. BIOCHEMISTRY
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Tau protein liquid–liquid phase separation can initiate tau aggregation
- (2018) Susanne Wegmann et al. EMBO JOURNAL
- RNA buffers the phase separation behavior of prion-like RNA binding proteins
- (2018) Shovamayee Maharana et al. SCIENCE
- Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
- (2018) Michael P. Hughes et al. SCIENCE
- Protein Phase Separation: A New Phase in Cell Biology
- (2018) Steven Boeynaems et al. TRENDS IN CELL BIOLOGY
- Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
- (2018) Ann Boija et al. CELL
- Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles
- (2017) Ming-Tzo Wei et al. Nature Chemistry
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
- (2017) Jacob P. Brady et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Liquid phase condensation in cell physiology and disease
- (2017) Yongdae Shin et al. SCIENCE
- Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau
- (2017) Susmitha Ambadipudi et al. Nature Communications
- Amyloid-like Self-Assembly of a Cellular Compartment
- (2016) Elvan Boke et al. CELL
- Coexisting Liquid Phases Underlie Nucleolar Subcompartments
- (2016) Marina Feric et al. CELL
- Phase separation in biology; functional organization of a higher order
- (2016) Diana M. Mitrea et al. Cell Communication and Signaling
- Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein
- (2016) Chi W. Pak et al. MOLECULAR CELL
- Membraneless organelles can melt nucleic acid duplexes and act as biomolecular filters
- (2016) Timothy J. Nott et al. Nature Chemistry
- Phase separation of signaling molecules promotes T cell receptor signal transduction
- (2016) Xiaolei Su et al. SCIENCE
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy
- (2016) Matthias Christoph Munder et al. eLife
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- RNA Controls PolyQ Protein Phase Transitions
- (2015) Huaiying Zhang et al. MOLECULAR CELL
- Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
- (2015) Yuan Lin et al. MOLECULAR CELL
- Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
- (2015) Kathleen A. Burke et al. MOLECULAR CELL
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
- (2015) Céline Galvagnion et al. Nature Chemical Biology
- Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles
- (2015) William M. Aumiller et al. Nature Chemistry
- Polymer physics of intracellular phase transitions
- (2015) Clifford P. Brangwynne et al. Nature Physics
- ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
- (2015) Tetsuro Murakami et al. NEURON
- Liquid-Liquid Phase Separation in Biology
- (2014) Anthony A. Hyman et al. Annual Review of Cell and Developmental Biology
- Solution conditions determine the relative importance of nucleation and growth processes in -synuclein aggregation
- (2014) A. K. Buell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phase transitions of multivalent proteins can promote clustering of membrane receptors
- (2014) Sudeep Banjade et al. eLife
- Analytical ultracentrifugation studies of oligomerization and DNA-binding of TtCarH, a Thermus thermophilus coenzyme B12-based photosensory regulator
- (2013) Ana I. Díez et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- N-terminal Acetylation Stabilizes N-terminal Helicity in Lipid- and Micelle-bound α-Synuclein and Increases Its Affinity for Physiological Membranes
- (2013) Igor Dikiy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impact of N-Terminal Acetylation of α-Synuclein on Its Random Coil and Lipid Binding Properties
- (2012) Alexander S. Maltsev et al. BIOCHEMISTRY
- Phase transitions in the assembly of multivalent signalling proteins
- (2012) Pilong Li et al. NATURE
- Taylor Dispersion Analysis Compared to Dynamic Light Scattering for the Size Analysis of Therapeutic Peptides and Proteins and Their Aggregates
- (2011) Andrea Hawe et al. PHARMACEUTICAL RESEARCH
- Flow Induced Dispersion Analysis Quantifies Noncovalent Interactions in Nanoliter Samples
- (2010) Henrik Jensen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Inertial microfluidics
- (2009) Dino Di Carlo LAB ON A CHIP
- Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation
- (2009) R. Narayanaswamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
- (2009) C. P. Brangwynne et al. SCIENCE
- Cell signaling, beyond cytosolic calcium in eukaryotes
- (2008) E PERMYAKOV et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- De Novo Formation of a Subnuclear Body
- (2008) T. E. Kaiser et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started