Ketamine increases activity of a fronto-striatal projection that regulates compulsive behavior in SAPAP3 knockout mice

Ketamine induces immediate and delayed alterations of OCD-like behavior

(2020) Summer L. Thompson et al.   PSYCHOPHARMACOLOGY

Basolateral amygdala input to the medial prefrontal cortex controls obsessive-compulsive disorder-like checking behavior

(2019) Tingting Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral orbitofrontal dysfunction in the Sapap3 knockout mouse model of obsessive–compulsive disorder

(2019) Huimeng Lei et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Strengthened inputs from secondary motor cortex to striatum in a mouse model of compulsive behavior

(2019) Victoria L. Corbit et al.   JOURNAL OF NEUROSCIENCE

Lower excitatory synaptic gene expression in orbitofrontal cortex and striatum in an initial study of subjects with obsessive compulsive disorder

(2019) Sean C. Piantadosi et al.   MOLECULAR PSYCHIATRY

The readily-releasable pool dynamically regulates multivesicular release

(2019) Jada H Vaden et al.   eLife

An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway

(2019) Sho Aoki et al.   eLife

A cortical-brainstem circuit predicts and governs compulsive alcohol drinking

(2019) Cody A. Siciliano et al.   SCIENCE

Aberrant habit formation in the Sapap3-knockout mouse model of obsessive-compulsive disorder

(2019) Lotfi C. Hadjas et al.   Scientific Reports

Dissociable Frontostriatal Connectivity: Mechanism and Predictor of the Clinical Efficacy of Capsulotomy in Obsessive-Compulsive Disorder

(2018) Dazhi Yin et al.   BIOLOGICAL PSYCHIATRY

Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

(2018) Panos Zanos et al.   PHARMACOLOGICAL REVIEWS

Associations of Observed Performance Monitoring During Preschool With Obsessive-Compulsive Disorder and Anterior Cingulate Cortex Volume Over 12 Years

(2018) Kirsten E. Gilbert et al.   JAMA Psychiatry

Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism

(2018) Nolan R. Williams et al.   AMERICAN JOURNAL OF PSYCHIATRY

Impaired instrumental reversal learning is associated with increased medial prefrontal cortex activity in Sapap3 knockout mouse model of compulsive behavior

(2018) Elizabeth E. Manning et al.   NEUROPSYCHOPHARMACOLOGY

Orbitofrontal Cortex: A Neural Circuit for Economic Decisions

(2017) Camillo Padoa-Schioppa et al.   NEURON

Neural correlates and structural markers of emotion dysregulation in traumatized civilians

(2017) Abigail Powers et al.   Social Cognitive and Affective Neuroscience

A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders

(2017) Gerard Sanacora et al.   JAMA Psychiatry

Cortico-striato-thalamo-cortical circuit abnormalities in obsessive-compulsive disorder: A voxel-based morphometric and fMRI study of the whole brain

(2016) Wenxin Tang et al.   BEHAVIOURAL BRAIN RESEARCH

The role of habit in compulsivity

(2016) Claire M. Gillan et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

Comparison of brain activation patterns during executive function tasks in hoarding disorder and non-hoarding OCD

(2016) Christina M. Hough et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression

(2015) D. Jeffrey Newport et al.   AMERICAN JOURNAL OF PSYCHIATRY

Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits

(2015) Talia N. Lerner et al.   CELL

DISSECTING OCD CIRCUITS: FROM ANIMAL MODELS TO TARGETED TREATMENTS

(2015) Susanne E. Ahmari et al.   DEPRESSION AND ANXIETY

Hyper-influence of the orbitofrontal cortex over the ventral striatum in obsessive-compulsive disorder

(2015) Yoshinari Abe et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Reductions in Cortico-Striatal Hyperconnectivity Accompany Successful Treatment of Obsessive-Compulsive Disorder with Dorsomedial Prefrontal rTMS

(2015) Katharine Dunlop et al.   NEUROPSYCHOPHARMACOLOGY

In vivo effects of ketamine on glutamate-glutamine and gamma-aminobutyric acid in obsessive-compulsive disorder: Proof of concept

(2015) Carolyn I. Rodriguez et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Motivation and value influences in the relative balance of goal-directed and habitual behaviours in obsessive-compulsive disorder

(2015) V Voon et al.   Translational Psychiatry

Decreased limbic and increased fronto-parietal connectivity in unmedicated patients with obsessive-compulsive disorder

(2014) Martin Göttlich et al.   HUMAN BRAIN MAPPING

Reduced functional connectivity within the limbic cortico-striato-thalamo-cortical loop in unmedicated adults with obsessive-compulsive disorder

(2013) Jonathan Posner et al.   HUMAN BRAIN MAPPING

The Expected Value of Control: An Integrative Theory of Anterior Cingulate Cortex Function

(2013) Amitai Shenhav et al.   NEURON

Randomized Controlled Crossover Trial of Ketamine in Obsessive-Compulsive Disorder: Proof-of-Concept

(2013) Carolyn I Rodriguez et al.   NEUROPSYCHOPHARMACOLOGY

Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

(2013) E. Burguiere et al.   SCIENCE

Repeated Cortico-Striatal Stimulation Generates Persistent OCD-Like Behavior

(2013) S. E. Ahmari et al.   SCIENCE

Disruption in the Balance Between Goal-Directed Behavior and Habit Learning in Obsessive-Compulsive Disorder

(2011) Claire M. Gillan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Sapap3 Deletion Anomalously Activates Short-Term Endocannabinoid-Mediated Synaptic Plasticity

(2011) M. Chen et al.   JOURNAL OF NEUROSCIENCE

The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication

(2008) A M Ruscio et al.   MOLECULAR PSYCHIATRY

Forward frontal fields: phylogeny and fundamental function

(2008) Steven P. Wise   TRENDS IN NEUROSCIENCES