Carbene-catalyzed atroposelective synthesis of axially chiral styrenes

N‐Heterocyclic Carbene‐Catalyzed Atroposelective Annulation for Access to Thiazine Derivatives with C‐N Axial Chirality

(2021) Tingting Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC‐Catalyzed Desymmetrization of N‐Aryl Maleimides Leading to the Atroposelective Synthesis of N‐Aryl Succinimides

(2021) Soumen Barik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Axially Chiral Benzothiophene/Benzofuran‐Fused Biaryls by N‐Heterocyclic Carbene Catalyzed Arene Formation

(2021) Chun‐Lin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Atroposelective Synthesis of Axially Chiral 4-Aryl α-Carbolines via N-Heterocyclic Carbene Catalysis

(2021) Rui Ma et al.   ORGANIC LETTERS

Carbene-Catalyzed Atroposelective Annulation and Desymmetrization of Urazoles

(2021) Jiamiao Jin et al.   ORGANIC LETTERS

Tandem Iridium Catalysis as a General Strategy for Atroposelective Construction of Axially Chiral Styrenes

(2021) Jie Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Synthesis of Axially Chiral Diarylmethylidene Indanones

(2021) Prashant Kumar et al.   ORGANIC LETTERS

Enantioselective Construction of Axially Chiral Amino Sulfide Vinyl Arenes by Chiral Sulfide-Catalyzed Electrophilic Carbothiolation of Alkynes

(2020) Yaoyu Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Axially Chiral Styrenes through Pd-Catalyzed Asymmetric C−H Olefination Enabled by an Amino Amide Transient Directing Group

(2020) Hong Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Enantioselective Construction of Heterocycle-Substituted Styrenes with Chiral Atropisomerism

(2020) Quan-Zhe Li et al.   ORGANIC LETTERS

Atroposelective Synthesis of Axially Chiral Styrenes via an Asymmetric C–H Functionalization Strategy

(2020) Liang Jin et al.   Chem

Axially Chiral Aryl‐Alkene‐Indole Framework: A Nascent Member of the Atropisomeric Family and Its Catalytic Asymmetric Construction

(2020) Cong‐Shuai Wang et al.   CHINESE JOURNAL OF CHEMISTRY

Atroposelective Access to Oxindole-Based Axially Chiral Styrenes via the Strategy of Catalytic Kinetic Resolution

(2020) Chun Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Cascade Reaction of o -Bromobenzaldehydes with N -Sulfonylhydrazones: An Efficient Approach to the Naphthalene Skeleton

(2019) Heng Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Construction of Axially Chiral 2-Arylpyrroles via Chirality Transfer of Atropisomeric Alkenes

(2019) Bin Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC-Catalyzed Atroposelective Acylation of Phenols: Access to Enantiopure NOBIN Analogs by Desymmetrization

(2019) Shenci Lu et al.   ORGANIC LETTERS

Rational design, enantioselective synthesis and catalytic applications of axially chiral EBINOLs

(2019) Yong-Bin Wang et al.   Nature Catalysis

Atroposelective Arene Formation by Carbene-Catalyzed Formal [4+2] Cycloaddition

(2019) Ke Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

(2019) Shenci Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Atropisomerism in medicinal chemistry: challenges and opportunities

(2018) Sean T Toenjes et al.   Future Medicinal Chemistry

Organocatalytic Enantioselective Construction of Axially Chiral Sulfone-Containing Styrenes

(2018) Shiqi Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes

(2018) Gregory Beutner et al.   ORGANIC LETTERS

Enantioselective synthesis of axially chiral vinyl arenes through palladium-catalyzed C–H olefination

(2018) Qiao-Ying Sun et al.   CHEMICAL COMMUNICATIONS

Atroposelective Catalytic Asymmetric Allylic Alkylation Reaction for Axially Chiral Anilides with Achiral Morita–Baylis–Hillman Carbonates

(2018) Shou-Lei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Mannich Reaction and Construction of Axially Chiral Sulfone-Containing Styrenes in One Pot from α-Amido Sulfones Based on the Waste–Reuse Strategy

(2018) Dongmei Li et al.   ORGANIC LETTERS

Enantioselective N-Heterocyclic Carbene-Catalyzed Kinetic Resolution of Anilides

(2018) Jianbo Bie et al.   ORGANIC LETTERS

Enantioselective Construction of Vicinal Diaxial Styrenes and Multiaxis System via Organocatalysis

(2018) Yu Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric One-Pot Construction of Three Stereogenic Elements: Chiral Carbon Center, Stereoisomeric Alkenes, and Chirality of Axial Styrenes

(2018) Anqi Huang et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Atroposelective Construction of Axially Chiral 1,4-Distyrene 2,3-Naphthalene Diols

(2018) Shan Li et al.   ORGANIC LETTERS

Catalytic enantioselective synthesis of atropisomeric biaryls by a cation-directed O-alkylation

(2017) John D. Jolliffe et al.   Nature Chemistry

Discovery and Assessment of Atropisomers of (±)-Lesinurad

(2017) Jianfei Wang et al.   ACS Medicinal Chemistry Letters

Stereoselective Arene-Forming Aldol Condensation: Synthesis of Axially Chiral Aromatic Amides

(2016) Vincent C. Fäseke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers

(2016) Scott H. Watterson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective Synthesis of Atropisomeric Vinyl Arene Compounds by Palladium Catalysis: A Carbene Strategy

(2015) Jia Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Stronger Brønsted Acids: Recent Progress

(2015) Takahiko Akiyama et al.   CHEMICAL REVIEWS

A twist of nature – the significance of atropisomers in biological systems

(2015) Jamie E. Smyth et al.   NATURAL PRODUCT REPORTS

N-Heterocyclic carbene catalysed redox isomerisation of esters to functionalised benzaldehydes

(2015) Lisa Candish et al.   Chemical Science

Kinetic Resolution of 1,1′-Biaryl-2,2′-Diols and Amino Alcohols through NHC-Catalyzed Atroposelective Acylation

(2014) Shenci Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Spontaneous transfer of chirality in an atropisomerically enriched two-axis system

(2014) Kimberly T. Barrett et al.   NATURE

Enantioselective Synthesis of Atropisomeric Benzamides through Peptide-Catalyzed Bromination

(2013) Kimberly T. Barrett et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Synthesis of Axially Chiral o-Iodoanilides by Phase-Transfer Catalyzed Alkylations

(2011) Seiji Shirakawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sulfones: new reagents in organocatalysis

(2010) Andrea-Nekane R. Alba et al.   CHEMICAL SOCIETY REVIEWS

Zinc Chloride-Promoted Aryl Bromide−Alkyne Cross-Coupling Reactions at Room Temperature

(2009) Aaron D. Finke et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent Progress in the Medicinal Chemistry of γ-Secretase Inhibitors

(2008) Richard Olson et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY