PURPL represses autophagic cell death to promote cutaneous melanoma by modulating ULK1 phosphorylation

Detection of aberrant splicing events in RNA-seq data using FRASER

(2021) Christian Mertes et al.   Nature Communications

Targeting apoptosis in cancer therapy

(2020) Benedito A. Carneiro et al.   Nature Reviews Clinical Oncology

The critical roles of lncRNAs in the pathogenesis of melanoma

(2020) Amin Safa et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Autophagy in Human Diseases

(2020) Noboru Mizushima et al.   NEW ENGLAND JOURNAL OF MEDICINE

The role of the LncRNA-FA2H-2-MLKL pathway in atherosclerosis by regulation of autophagy flux and inflammation through mTOR-dependent signaling

(2019) Feng-Xia Guo et al.   CELL DEATH AND DIFFERENTIATION

MALAT1-KTN1-EGFR regulatory axis promotes the development of cutaneous squamous cell carcinoma

(2019) Ying Zhang et al.   CELL DEATH AND DIFFERENTIATION

LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in colorectal cancer cells

(2019) Xinke Wang et al.   Cancer Cell International

HOXA9 Transcriptionally Promotes Apoptosis and Represses Autophagy by Targeting NF-κB in Cutaneous Squamous Cell Carcinoma

(2019) Shuo Han et al.   Cells

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis

(2018) Fengting Huang et al.   Molecular Cancer

RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas

(2018) Manfred Kunz et al.   ONCOGENE

HOXA9 inhibits HIF-1α-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development

(2018) Liang Zhou et al.   Nature Communications

Melanoma

(2018) Dirk Schadendorf et al.   LANCET

LncRNA MALAT1 protects cardiomyocytes from isoproterenol‐induced apoptosis through sponging miR‐558 to enhance ULK1‐mediated protective autophagy

(2018) Xiaoyan Guo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors

(2017) Aifu Lin et al.   NATURE CELL BIOLOGY

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

(2017) Rhianna C. Laker et al.   Nature Communications

Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer

(2017) Xiao Ling Li et al.   Cell Reports

Long Non-coding RNA H19 Induces Cerebral Ischemia Reperfusion Injury via Activation of Autophagy

(2017) Jue Wang et al.   Aging and Disease

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

AMPK–ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells

(2016) Ji Eun Jang et al.   CLINICAL CANCER RESEARCH

Down-regulation of Risa improves insulin sensitivity by enhancing autophagy

(2016) Yuangao Wang et al.   FASEB JOURNAL

Melanoma addiction to the long non-coding RNA SAMMSON

(2016) Eleonora Leucci et al.   NATURE

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

(2016) Aifu Lin et al.   NATURE CELL BIOLOGY

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

(2016) Xiaowen Liu et al.   NATURE CELL BIOLOGY

Suppression of hepatocellular carcinoma by baculovirus-mediated expression of long non-coding RNA PTENP1 and MicroRNA regulation

(2015) Chiu-Ling Chen et al.   BIOMATERIALS

Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1

(2015) Liang Zhou et al.   Nature Communications

Melanoma

(2015) Dirk Schadendorf et al.   Nature Reviews Disease Primers

Autosis and autophagic cell death: the dark side of autophagy

(2014) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

miR-14 Regulates Autophagy during Developmental Cell Death by Targeting ip3-kinase 2

(2014) Charles Nelson et al.   MOLECULAR CELL

The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation

(2014) P. Wang et al.   SCIENCE

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

(2013) Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival

(2011) Mohamed Elgendy et al.   MOLECULAR CELL

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY