Construction of a Protoberberine Alkaloid Skeleton via the Palladium-Catalyzed α-Arylation–Amide Formation Cascade

Construction of Protoberberine Alkaloid Core through Palladium Carbene Bridging C–H Bond Functionalization and Pyridine Dearomatization

(2021) Luoting Xin et al.   ACS Catalysis

Modular and Divergent Syntheses of Protoberberine and Protonitidine Alkaloids

(2021) Kai Liu et al.   ORGANIC LETTERS

Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**

(2021) Guoli He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

TfOH-Promoted Decyanative Cyclization toward the Synthesis of 2,1-Benzisoxazoles

(2021) Mengge Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines

(2020) Aaron Trowbridge et al.   CHEMICAL REVIEWS

Total Synthesis of (+)-Aspidospermidine

(2019) Hongjin Xu et al.   ORGANIC LETTERS

Two Cocrystals of Berberine Chloride with Myricetin and Dihydromyricetin: Crystal Structures, Characterization, and Antitumor Activities

(2019) Peizhe Li et al.   CRYSTAL GROWTH & DESIGN

Total Synthesis of Two 8-Oxoprotoberberine Alkaloids: Alangiumkaloids A and B

(2018) Takashi Nishiyama et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Unified Strategy for the Syntheses of the Isoquinolinium Alkaloids Berberine, Coptisine, and Jatrorrhizine

(2018) Luis M. Mori-Quiroz et al.   ORGANIC LETTERS

Cesium carbonate promoted cascade reaction involving DMF as a reactant for the synthesis of dihydropyrrolizino[3,2-b]indol-10-ones

(2018) Qianqian Zhang et al.   Organic Chemistry Frontiers

Comparison of anti-inflammatory effects of berberine, and its natural oxidative and reduced derivatives from Rhizoma Coptidis in vitro and in vivo

(2018) Cai-Lan Li et al.   PHYTOMEDICINE

Methylenecyclopropane Ring Formation/Opening Cascade for the Synthesis of Indolizines

(2017) Congjun Zhu et al.   JOURNAL OF ORGANIC CHEMISTRY

A Palladium-Catalyzed Monodearoylative Dimerization Approach for the Synthesis of [3]Dendralenes

(2017) Tiantian Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Cascade C–H Annulation of Aldoximes with Alkynes Using O2 as the Sole Oxidant: One-Pot Access to Multisubstituted Protoberberine Skeletons

(2017) Junbin Tang et al.   ORGANIC LETTERS

Total Synthesis of Camptothecin and Related Natural Products by a Flexible Strategy

(2016) Ke Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Isoquinoline Alkaloids: 2004–2015

(2016) Maria Chrzanowska et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

(2016) Jian He et al.   CHEMICAL REVIEWS

Mild metal-catalyzed C–H activation: examples and concepts

(2016) T. Gensch et al.   CHEMICAL SOCIETY REVIEWS

A General, Concise Strategy that Enables Collective Total Syntheses of over 50 Protoberberine and Five Aporhoeadane Alkaloids within Four to Eight Steps

(2016) Shiqiang Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Divergent Syntheses of Carbazole Alkaloids Clausenapin, Indizoline, Claulansine M, and Clausenaline D

(2016) Yizhen Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 2-Cyclopentenone Derivatives via Palladium-Catalyzed Intramolecular Carbonyl α-Alkenylation

(2016) Panpan Chen et al.   ORGANIC LETTERS

Total Syntheses of Carbazole Alkaloids Lansine F and Clauemarazole D

(2016) Yanqin Guo et al.   Asian Journal of Organic Chemistry

Direct Synthesis of Protoberberine Alkaloids by Rh-Catalyzed C−H Bond Activation as the Key Step

(2015) Jayachandran Jayakumar et al.   CHEMISTRY-A EUROPEAN JOURNAL

A One-Pot Cascade to Protoberberine Alkaloids via Stevens Rearrangement of Nitrile-Stabilized Ammonium Ylides

(2015) Günther Lahm et al.   JOURNAL OF ORGANIC CHEMISTRY

Cytotoxicity of alkaloids isolated fromArgemone mexicanaon SW480 human colon cancer cell line

(2015) Sarita Singh et al.   PHARMACEUTICAL BIOLOGY

Transition Metal-Free Cascade Reactions of Alkynols to Afford Isoquinolin-1(2H)-one and Dihydroisobenzofuran Derivatives

(2014) Deng Yuan Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium-Catalyzed Intermolecular C-H Silylation of Arenes with High Steric Regiocontrol

(2014) C. Cheng et al.   SCIENCE

Berberine: New perspectives for old remedies

(2012) Micol Tillhon et al.   BIOCHEMICAL PHARMACOLOGY

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

Progress in palladium-based catalytic systems for the sustainable synthesis of annulated heterocycles: a focus on indole backbones

(2012) Mélanie Platon et al.   CHEMICAL SOCIETY REVIEWS

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Berberine induces cell death in human hepatoma cells in vitro by downregulating CD147

(2011) Qian Hou et al.   CANCER SCIENCE

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Mild and General Method for the α-Arylation of Heteroaromatic Ketones

(2010) Lopa V. Desai et al.   ORGANIC LETTERS

Transition Metal-Catalyzed Direct Arylation of Substrates with Activated sp3-Hybridized C−H Bonds and Some of Their Synthetic Equivalents with Aryl Halides and Pseudohalides

(2009) Fabio Bellina et al.   CHEMICAL REVIEWS

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS

Radical-initiated cyclization as a key step for the synthesis of oxoprotoberberine alkaloids

(2009) Chih-Shone Lee et al.   TETRAHEDRON LETTERS