Modular and Divergent Syntheses of Protoberberine and Protonitidine Alkaloids

Merging C–H Vinylation with Switchable 6π-Electrocyclizations for Divergent Heterocycle Synthesis

(2020) Xunjin Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxalic Diamides and tert-Butoxide: Two Types of Ligands Enabling Practical Access to Alkyl Aryl Ethers via Cu-Catalyzed Coupling Reaction

(2019) Zhixiang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Controlled Palladium(II)-Catalyzed Regiodivergent Carbonylation of Alkynes: Syntheses of Indolo[3,2-c ]coumarins and Benzofuro[3,2-c ]quinolinones

(2018) Dong Ding et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and biological evaluation of new berberine derivatives as cancer immunotherapy agents through targeting IDO1

(2018) Yan–Xiang Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Exploiting Ancillary Ligation To Enable Nickel-Catalyzed C–O Cross-Couplings of Aryl Electrophiles with Aliphatic Alcohols

(2018) Preston M. MacQueen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unified Strategy for the Syntheses of the Isoquinolinium Alkaloids Berberine, Coptisine, and Jatrorrhizine

(2018) Luis M. Mori-Quiroz et al.   ORGANIC LETTERS

Cascade C–H Annulation of Aldoximes with Alkynes Using O2 as the Sole Oxidant: One-Pot Access to Multisubstituted Protoberberine Skeletons

(2017) Junbin Tang et al.   ORGANIC LETTERS

A Selective C−H Deprotonation Strategy to Access Functionalized Arynes by Using Hypervalent Iodine

(2016) Sunil K. Sundalam et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A General, Concise Strategy that Enables Collective Total Syntheses of over 50 Protoberberine and Five Aporhoeadane Alkaloids within Four to Eight Steps

(2016) Shiqiang Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of vinyl ethers of alcohols using calcium carbide under superbasic catalytic conditions (KOH/DMSO)

(2016) Ryosuke Matake et al.   GREEN CHEMISTRY

Copper-Catalyzed Hydroxylation of (Hetero)aryl Halides under Mild Conditions

(2016) Shanghua Xia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Utility of Ligand Effect in Homogenous Gold Catalysis: Enabling Regiodivergent π-Bond-Activated Cyclization

(2016) Dong Ding et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand Controlled Regiodivergent C1Insertion on Arynes for Construction of Phenanthridinone and Acridone Alkaloids

(2015) Minghao Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyridynes and indolynes as building blocks for functionalized heterocycles and natural products

(2015) Adam E. Goetz et al.   CHEMICAL COMMUNICATIONS

Direct Synthesis of Protoberberine Alkaloids by Rh-Catalyzed C−H Bond Activation as the Key Step

(2015) Jayachandran Jayakumar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and Structure–Activity Relationships of Quaternary Coptisine Derivatives as Potential Anti-ulcerative Colitis Agents

(2015) Zhi-Hui Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

A One-Pot Cascade to Protoberberine Alkaloids via Stevens Rearrangement of Nitrile-Stabilized Ammonium Ylides

(2015) Günther Lahm et al.   JOURNAL OF ORGANIC CHEMISTRY

Switching on elusive organometallic mechanisms with photoredox catalysis

(2015) Jack A. Terrett et al.   NATURE

A room-temperature protocol to access isoquinolines through Ag(i) catalysed annulation of o-(1-alkynyl)arylaldehydes and ketones with NH4OAc: elaboration to berberine and palmatine

(2015) Virsinha Reddy et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation

(2014) Alice E. Gatland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Synthesis and Applications of N-Heteroaryl Iodonium Salts

(2014) Marcin Bielawski et al.   ChemistryOpen

Modular Isoquinoline Synthesis Using Catalytic Enolate Arylation and in Situ Functionalization

(2013) Ben S. Pilgrim et al.   ORGANIC LETTERS

Synthesis of substituted isoquinolines utilizing palladium-catalyzed  -arylation of ketones

(2012) T. J. Donohoe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Single Phosphine Ligand Allows Palladium-Catalyzed Intermolecular CO Bond Formation with Secondary and Primary Alcohols

(2011) Xiaoxing Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-catalyzed tandem reaction to construct benzo[c]phenanthridine: application to the total synthesis of benzo[c]phenanthridine alkaloids

(2011) Pei Lv et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A General and Efficient Catalyst for Palladium-Catalyzed C−O Coupling Reactions of Aryl Halides with Primary Alcohols

(2010) Saravanan Gowrisankar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis of benzo[c]phenanthridine alkaloids based on a microwave-assisted electrocyclic reaction of the aza 6π-electron system and structural revision of broussonpapyrine

(2010) Yuhsuke Ishihara et al.   TETRAHEDRON

An Efficient Ullmann-Type C−O Bond Formation Catalyzed by an Air-Stable Copper(I)−Bipyridyl Complex

(2008) Jiajia Niu et al.   JOURNAL OF ORGANIC CHEMISTRY