Direct Synthesis of Protoberberine Alkaloids by Rh-Catalyzed C−H Bond Activation as the Key Step

Rhodium(III)-Catalyzed [3+2]/[5+2] Annulation of 4-Aryl 1,2,3-Triazoles with Internal Alkynes through Dual C(sp2)H Functionalization

(2015) Yuan Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A One-Pot Cascade to Protoberberine Alkaloids via Stevens Rearrangement of Nitrile-Stabilized Ammonium Ylides

(2015) Günther Lahm et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium(III)-Catalyzed Vinylic C–H Activation: A Direct Route toward Pyridinium Salts

(2015) Ching-Zong Luo et al.   ORGANIC LETTERS

One-Pot Synthesis of Highly Substituted Polyheteroaromatic Compounds by Rhodium(III)-Catalyzed Multiple CH Activation and Annulation

(2014) Jayachandran Jayakumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation

(2014) Alice E. Gatland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aromatic Homologation by Non-Chelate-Assisted RhIII-Catalyzed CH Functionalization of Arenes with Alkynes

(2014) Manh V. Pham et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh(iii)-Catalyzed intramolecular redox-neutral cyclization of alkenes via C–H activation

(2014) Zhuangzhi Shi et al.   CHEMICAL COMMUNICATIONS

Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations

(2013) Lutz Ackermann   ACCOUNTS OF CHEMICAL RESEARCH

Rhodium-Catalyzed Oxidative Annulation of Sulfoximines and Alkynes as an Approach to 1,2-Benzothiazines

(2013) Wanrong Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Intramolecular Hydroarylation, Amidoarylation, and Heck-type Reaction: Three Distinct Pathways Determined by an Amide Directing Group

(2013) Tyler A. Davis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Cp-Rhodium(III)-Catalyzed Asymmetric Hydroarylations of 1,1-Disubstituted Alkenes

(2013) Baihua Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mild Rhodium(III)-Catalyzed Cyclization of Amides with α,β-Unsaturated Aldehydes and Ketones to Azepinones: Application to the Synthesis of the Homoprotoberberine Framework

(2013) Zhuangzhi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A convenient synthesis of quinolizinium salts through Rh(iii) or Ru(ii)-catalyzed C–H bond activation of 2-alkenylpyridines

(2013) Ching-Zong Luo et al.   CHEMICAL COMMUNICATIONS

A General Method to Diverse Cinnolines and Cinnolinium Salts

(2013) Dongbing Zhao et al.   CHEMISTRY-A EUROPEAN JOURNAL

RhIII-Catalyzed CH Activation: A Versatile Route towards Various Polycyclic Pyridinium Salts

(2013) Ching-Zong Luo et al.   CHEMISTRY-A EUROPEAN JOURNAL

HPLC-MS Analysis of Ethanol Extract of Corydalis yanhusuo and Simultaneous Determination of Eight Protoberberine Quaternary Alkaloids by HPLC-DAD

(2013) X.-y. Cheng et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

An Efficient Rh/O2 Catalytic System for Oxidative C–H Activation/Annulation: Evidence for Rh(I) to Rh(III) Oxidation by Molecular Oxygen

(2013) Guoying Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(iii)-catalyzed intramolecular annulations involving amide-directed C–H activations: synthetic scope and mechanistic studies

(2013) Noelia Quiñones et al.   Chemical Science

Functionalization of C sp 3H and C sp 2H Bonds: Synthesis of Spiroindenes by Enolate-Directed Ruthenium-Catalyzed Oxidative Annulation of Alkynes with 2-Aryl-1,3-dicarbonyl Compounds

(2012) Suresh Reddy Chidipudi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Direction in CH Alkenylation: Silanol as a Helping Hand

(2012) Marius Mewald et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Intramolecular Annulation through CH Activation: Total Synthesis of (±)-Antofine, (±)-Septicine, (±)-Tylophorine, and Rosettacin

(2012) Xianxiu Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mild Rhodium(III)-Catalyzed CH Activation and Intermolecular Annulation with Allenes

(2012) Honggen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium-Catalyzed Oxidative Coupling/Cyclization of Isoquinolones with Alkynes through CH/NH Activation: Mechanism Study and Synthesis of Dibenzo[a,g]quinolizin-8-one Derivatives

(2012) Bin Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis, structure–activity relationship and in vitro anti-mycobacterial evaluation of 13-n-octylberberine derivatives

(2012) Yan-Xin Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ru(II)-Catalyzed C–H Bond Activation for the Synthesis of Substituted Isoquinolinium Salts from Benzaldehydes, Amines, and Alkynes

(2012) Kanniyappan Parthasarathy et al.   ORGANIC LETTERS

Versatile Pyrrole Synthesis through Ruthenium(II)-Catalyzed Alkene C–H Bond Functionalization on Enamines

(2012) Lianhui Wang et al.   ORGANIC LETTERS

Versatile Synthesis of Isocoumarins and α-Pyrones by Ruthenium-Catalyzed Oxidative C–H/O–H Bond Cleavages

(2012) Lutz Ackermann et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Highly Regioselective Cyclization of Ketoximes with Alkynes by C–H Bond Activation: A Practical Route to Synthesize Substituted Isoquinolines

(2012) Ravi Kiran Chinnagolla et al.   ORGANIC LETTERS

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

One-Pot Synthesis of Isoquinolinium Salts by Rhodium-Catalyzed CH Bond Activation: Application to the Total Synthesis of Oxychelerythrine

(2011) Jayachandran Jayakumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium-Catalyzed Oxidative Annulation by Cleavage of CH/NH Bonds

(2011) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Pictet-Spengler Reaction in Nature and in Organic Chemistry

(2011) Joachim Stöckigt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective synthesis of isocoumarins by ruthenium-catalyzed aerobic oxidative cyclization of aromatic acids with alkynes

(2011) Ravi Kiran Chinnagolla et al.   CHEMICAL COMMUNICATIONS

Intermolecular Dehydrogenative Heck Reactions

(2011) Jean Le Bras et al.   CHEMICAL REVIEWS

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

Towards mild metal-catalyzed C–H bond activation

(2011) Joanna Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium-Catalyzed Isoquinolone Synthesis through CH Activation Using an Oxidizing Directing Group

(2011) Bin Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ruthenium-Catalyzed Regioselective Cyclization of Aromatic Ketones with Alkynes: An Efficient Route to Indenols and Benzofulvenes

(2011) Ravi Kiran Chinnagolla et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Ruthenium-Catalyzed Oxidative Synthesis of 2-Pyridones through C–H/N–H Bond Functionalizations

(2011) Lutz Ackermann et al.   ORGANIC LETTERS

Synthesis of 1-Aminoisoquinolines via Rh(III)-Catalyzed Oxidative Coupling

(2011) Xiaohong Wei et al.   ORGANIC LETTERS

Ruthenium-Catalyzed C–H/N–O Bond Functionalization: Green Isoquinolone Syntheses in Water

(2011) Lutz Ackermann et al.   ORGANIC LETTERS

Ruthenium-catalyzed aerobic oxidative coupling of alkynes with 2-aryl-substituted pyrroles

(2011) Lutz Ackermann et al.   Chemical Science

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis

(2010) Tetsuya Satoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Naphtho[1,8-bc]pyran Derivatives and Related Compounds through Hydroxy Group Directed CH Bond Cleavage under Rhodium Catalysis

(2010) Satoshi Mochida et al.   Chemistry-An Asian Journal

Rhodium(III)-Catalyzed Isoquinolone Synthesis: The N−O Bond as a Handle for C−N Bond Formation and Catalyst Turnover

(2010) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Arene and Alkene C−H Bond Functionalization Leading to Indoles and Pyrroles

(2010) David R. Stuart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Oxidative Cycloaddition of Benzamides and Alkynes via C−H/N−H Activation

(2010) Todd K. Hyster et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pyrrole Synthesis via Allylic sp3C−H Activation of Enamines Followed by Intermolecular Coupling with Unactivated Alkynes

(2010) Souvik Rakshit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 2-Pyridones and Iminoesters via Rh(III)-Catalyzed Oxidative Coupling between Acrylamides and Alkynes

(2010) Yan Su et al.   ORGANIC LETTERS

Rhodium-Catalyzed Oxidative Coupling/Cyclization of 2-Phenylindoles with Alkynes via C−H and N−H Bond Cleavages with Air as the Oxidant

(2010) Keisuke Morimoto et al.   ORGANIC LETTERS

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS

Protecting-Group-Free Total Synthesis of Isoquinoline Alkaloids by Nickel-Catalyzed Annulation ofo-Halobenzaldimine with an Alkyne as the Key Step

(2009) Rajendra Prasad Korivi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Functionalized α-Pyrone and Butenolide Derivatives by Rhodium-Catalyzed Oxidative Coupling of Substituted Acrylic Acids with Alkynes and Alkenes

(2009) Satoshi Mochida et al.   JOURNAL OF ORGANIC CHEMISTRY

Ligand-Enabled Reactivity and Selectivity in a Synthetically Versatile Aryl C-H Olefination

(2009) D.-H. Wang et al.   SCIENCE

Fluorescent Naphthyl- and Anthrylazoles from the Catalytic Coupling of Phenylazoles with Internal Alkynes through the Cleavage of Multiple CH Bonds

(2008) Nobuyoshi Umeda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and structure–activity relationships of novel, substituted 5,6-dihydrodibenzo[a,g]quinolizinium P2X7 antagonists

(2008) Ga Eun Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Palmatine, a protoberberine alkaloid, inhibits both Ca2+- and cAMP-activated Cl− secretion in isolated rat distal colon

(2008) D Z Wu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Berberine Analogues as a Novel Class of the Low-Density-Lipoprotein Receptor Up-Regulators: Synthesis, Structure−Activity Relationships, and Cholesterol-Lowering Efficacy

(2008) Ying-Hong Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

An Efficient Low-Temperature Route to Polycyclic Isoquinoline Salt Synthesis via C−H Activation with [Cp*MCl2]2(M = Rh, Ir)

(2008) Ling Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Indole Synthesis via Rhodium Catalyzed Oxidative Coupling of Acetanilides and Internal Alkynes

(2008) David R. Stuart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY