VSL#3 Probiotic Stimulates T-cell Protein Tyrosine Phosphatase–mediated Recovery of IFN-γ–induced Intestinal Epithelial Barrier Defects

IBD Candidate Genes and Intestinal Barrier Regulation

(2014) Declan F. McCole   INFLAMMATORY BOWEL DISEASES

The Probiotic Mixture VSL#3 Dampens LPS-Induced Chemokine Expression in Human Dendritic Cells by Inhibition of STAT-1 Phosphorylation

(2014) Rob Mariman et al.   PLoS One

Combined Serological, Genetic, and Inflammatory Markers Differentiate Non-IBD, Crohnʼs Disease, and Ulcerative Colitis Patients

(2013) Scott Plevy et al.   INFLAMMATORY BOWEL DISEASES

Spermidine Stimulates T Cell Protein-tyrosine Phosphatase-mediated Protection of Intestinal Epithelial Barrier Function

(2013) Harrison M. Penrose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2

(2012) Declan F. McCole   Annals of the New York Academy of Sciences

Probiotics Are Effective for the Prevention and Treatment of Citrobacter rodentium–Induced Colitis in Mice

(2012) David M. Rodrigues et al.   JOURNAL OF INFECTIOUS DISEASES

VSL#3 probiotics exerts the anti-inflammatory activity via PI3k/Akt and NF-κB pathway in rat model of DSS-induced colitis

(2012) Cong Dai et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background

(2012) Jürgen Glas et al.   PLoS One

Probiotic Bacteria Produce Conjugated Linoleic Acid Locally in the Gut That Targets Macrophage PPAR γ to Suppress Colitis

(2012) Josep Bassaganya-Riera et al.   PLoS One

Probiotic Bacteria Regulate Intestinal Epithelial Permeability in Experimental Ileitis by a TNF-Dependent Mechanism

(2012) Daniele Corridoni et al.   PLoS One

Crohnʼs disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy

(2011) Michael Scharl et al.   INFLAMMATORY BOWEL DISEASES

Treatment of Relapsing Mild-to-Moderate Ulcerative Colitis With the Probiotic VSL#3 as Adjunctive to a Standard Pharmaceutical Treatment: A Double-Blind, Randomized, Placebo-Controlled Study

(2010) Antonio Tursi et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Probiotic bacteria and intestinal epithelial barrier function

(2010) Christina L. Ohland et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

(2010) Elina Mattila et al.   BMC CANCER

Cell cycle-dependent regulation of SFK, JAK1 and STAT3 signaling by the protein tyrosine phosphatase TCPTP

(2010) Ben J. Shields et al.   CELL CYCLE

Probiotic lactobacilli and VSL#3 induce enterocyte β-defensin 2

(2010) M. Schlee et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Posttranslational Inhibition of Proinflammatory Chemokine Secretion in Intestinal Epithelial Cells

(2010) Gabriele Hörmannsperger et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of a Probiotic Preparation (VSL#3) on Induction and Maintenance of Remission in Children With Ulcerative Colitis

(2009) Erasmo Miele et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Probiotic mixture VSL#3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis

(2009) Rudolf Mennigen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effect of Probiotics on Intestinal Barrier Function

(2009) Rudolf Mennigen et al.   Annals of the New York Academy of Sciences

Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2

(2009) Michael Scharl et al.   GASTROENTEROLOGY

Interferon-γ Regulation of Intestinal Epithelial Permeability

(2009) Cécile Beaurepaire et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Post-Translational Inhibition of IP-10 Secretion in IEC by Probiotic Bacteria: Impact on Chronic Inflammation

(2009) Gabriele Hörmannsperger et al.   PLoS One

Probiotics promote gut health through stimulation of epithelial innate immunity

(2009) C. Pagnini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secreted bioactive factors from Bifidobacterium infantis enhance epithelial cell barrier function

(2008) Julia B. Ewaschuk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Probiotic administration in patients with ileal pouch–anal anastomosis for ulcerative colitis is associated with expansion of mucosal regulatory cells

(2008) Annamaria Pronio et al.   INFLAMMATORY BOWEL DISEASES

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

(2008) Andre Franke et al.   NATURE GENETICS

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

(2008) Deborah J. Smyth et al.   NEW ENGLAND JOURNAL OF MEDICINE