Irg1/itaconate metabolic pathway is a crucial determinant of dendritic cells immune-priming function and contributes to resolute allergen-induced airway inflammation
出版年份 2021 全文链接
标题
Irg1/itaconate metabolic pathway is a crucial determinant of dendritic cells immune-priming function and contributes to resolute allergen-induced airway inflammation
作者
关键词
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出版物
Mucosal Immunology
Volume 15, Issue 2, Pages 301-313
出版商
Springer Science and Business Media LLC
发表日期
2021-10-21
DOI
10.1038/s41385-021-00462-y
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cyclic-di-GMP Induces STING-Dependent ILC2 to ILC1 Shift During Innate Type 2 Lung Inflammation
- (2021) Kellen J. Cavagnero et al. Frontiers in Immunology
- IRG1/Itaconate Activates Nrf2 in Hepatocytes to Protect Against Liver Ischemia–Reperfusion Injury
- (2020) Zhongjie Yi et al. HEPATOLOGY
- Pyruvate Kinase M2 in lung APCs regulates Alternaria-induced airway inflammation
- (2020) Anil Kumar Jaiswal et al. IMMUNOBIOLOGY
- Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response
- (2020) Kaitlyn A Sun et al. eLife
- The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
- (2020) Alexander Hooftman et al. Cell Metabolism
- Itaconate prevents abdominal aortic aneurysm formation through inhibiting inflammation via activation of Nrf2
- (2020) Haoyu Song et al. EBioMedicine
- Itaconate controls the severity of pulmonary fibrosis
- (2020) Patricia P. Ogger et al. Science Immunology
- 4-Octyl itaconate (4-OI) attenuates lipopolysaccharide-induced acute lung injury by suppressing PI3K/Akt/NF-κB signaling pathways in mice
- (2020) Yan Xin et al. Experimental and Therapeutic Medicine
- 4-Octyl Itaconate Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice by Inhibiting Oxidative Stress and Inflammation
- (2020) Yang Li et al. Drug Design Development and Therapy
- The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons
- (2019) Brian P. Daniels et al. IMMUNITY
- The Global Initiative for Asthma (GINA): 25 years later
- (2019) Louis-Philippe Boulet et al. EUROPEAN RESPIRATORY JOURNAL
- Metabolic Control of Dendritic Cell Functions: Digesting Information
- (2019) Stefanie K. Wculek et al. Frontiers in Immunology
- The Immunomodulatory Potential of the Metabolite Itaconate
- (2019) Alexander Hooftman et al. TRENDS IN IMMUNOLOGY
- Irg1expression in myeloid cells prevents immunopathology duringM. tuberculosisinfection
- (2018) Sharmila Nair et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells
- (2018) Marine Oberkampf et al. Nature Communications
- Manifold Roles of CCR7 and Its Ligands in the Induction and Maintenance of Bronchus-Associated Lymphoid Tissue
- (2018) Henrike Fleige et al. Cell Reports
- Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cells
- (2018) Kenneth P. Hough et al. Redox Biology
- Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors
- (2018) Jonathan M. Weiss et al. JOURNAL OF CLINICAL INVESTIGATION
- Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis
- (2018) Monika Bambouskova et al. NATURE
- Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
- (2018) Evanna L. Mills et al. NATURE
- Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming
- (2018) David Olagnier et al. Nature Communications
- The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity
- (2018) Jorge Domínguez-Andrés et al. Cell Metabolism
- STING-dependent sensing of self-DNA drives silica-induced lung inflammation
- (2018) Sulayman Benmerzoug et al. Nature Communications
- IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species
- (2017) Xing Liu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Low-density lipoprotein receptor–related protein 1 attenuates house dust mite–induced eosinophilic airway inflammation by suppressing dendritic cell–mediated adaptive immune responses
- (2017) Amarjit Mishra et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation
- (2017) Charles Sinclair et al. SCIENCE
- Glucose represses dendritic cell-induced T cell responses
- (2017) Simon J. Lawless et al. Nature Communications
- Metabolic Plasticity in Dendritic Cell Responses: Implications in Allergic Asthma
- (2017) Amarjit Mishra Journal of Immunology Research
- Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
- (2016) Vicky Lampropoulou et al. Cell Metabolism
- Suppression of IRG-1 Reduces Inflammatory Cell Infiltration and Lung Injury in Respiratory Syncytial Virus Infection by Reducing Production of Reactive Oxygen Species
- (2016) Ke Ren et al. JOURNAL OF VIROLOGY
- Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages
- (2016) Aravind Tallam et al. PLoS One
- IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid
- (2016) Jan Naujoks et al. PLoS Pathogens
- Distinct endotypes of steroid-resistant asthma characterized by IL-17Ahigh and IFN-γhigh immunophenotypes: Potential benefits of calcitriol
- (2015) Emma S. Chambers et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- High IFN-γ and low SLPI mark severe asthma in mice and humans
- (2015) Mahesh Raundhal et al. JOURNAL OF CLINICAL INVESTIGATION
- Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase
- (2015) Amarjit Mishra et al. Nature Communications
- Platelets from Asthmatic Individuals Show Less Reliance on Glycolysis
- (2015) Weiling Xu et al. PLoS One
- Mitochondrial Structural Changes and Dysfunction Are Associated with Experimental Allergic Asthma
- (2014) U. Mabalirajan et al. JOURNAL OF IMMUNOLOGY
- Bacterial itaconate degradation promotes pathogenicity
- (2014) Jahminy Sasikaran et al. Nature Chemical Biology
- TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation
- (2014) Bart Everts et al. NATURE IMMUNOLOGY
- Immune responsive gene 1, a novel oncogene, increases the growth and tumorigenicity of glioma
- (2014) JUN PAN et al. ONCOLOGY REPORTS
- Potentially Pathogenic Airway Bacteria and Neutrophilic Inflammation in Treatment Resistant Severe Asthma
- (2014) Benjamin J. Green et al. PLoS One
- Causal analysis approaches in Ingenuity Pathway Analysis
- (2013) Andreas Krämer et al. BIOINFORMATICS
- Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling
- (2013) Laura A. Sena et al. IMMUNITY
- Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen
- (2013) Maud Plantinga et al. IMMUNITY
- Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species
- (2013) Yingke Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Critical Role of the Tumor Suppressor Tuberous Sclerosis Complex 1 in Dendritic Cell Activation of CD4 T Cells by Promoting MHC Class II Expression via IRF4 and CIITA
- (2013) H. Pan et al. JOURNAL OF IMMUNOLOGY
- Dectin-2 sensing of house dust mite is critical for the initiation of airway inflammation
- (2013) D L Clarke et al. Mucosal Immunology
- Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses
- (2013) Hyelim Cho et al. NATURE MEDICINE
- Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
- (2013) A. Michelucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Asthma heterogeneity and severity—why is comprehensive phenotyping important?
- (2013) Wendy C Moore et al. Lancet Respiratory Medicine
- A Large Subgroup of Mild-to-Moderate Asthma Is Persistently Noneosinophilic
- (2012) Kelly Wong McGrath et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
- (2012) B. Everts et al. BLOOD
- Asthma phenotypes: the evolution from clinical to molecular approaches
- (2012) Sally E Wenzel NATURE MEDICINE
- A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue
- (2012) Min Yuan et al. Nature Protocols
- Interleukin-10 Alters Effector Functions of Multiple Genes Induced by Borrelia burgdorferi in Macrophages To Regulate Lyme Disease Inflammation
- (2011) Aarti Gautam et al. INFECTION AND IMMUNITY
- Sirtuin 1 Promotes Th2 Responses and Airway Allergy by Repressing Peroxisome Proliferator-Activated Receptor- Activity in Dendritic Cells
- (2011) A. Legutko et al. JOURNAL OF IMMUNOLOGY
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
- (2010) C. M. Krawczyk et al. BLOOD
- Aspergillus fumigatus regulates mite allergen-pulsed dendritic cells in the development of asthma
- (2010) S. Fukahori et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes
- (2010) Annette T. Hastie et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- CD11c depletion severely disrupts Th2 induction and development in vivo
- (2010) Alexander T. Phythian-Adams et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Biology of Lung Dendritic Cells at the Origin of Asthma
- (2009) Bart N. Lambrecht et al. IMMUNITY
- Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis
- (2009) L. van der Fits et al. JOURNAL OF IMMUNOLOGY
- The Proinflammatory Cytokine-Induced IRG1 Protein Associates with Mitochondria
- (2008) Daniel Degrandi et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
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