Hydroamination, Aminoboration, and Carboamination with Electrophilic Amination Reagents: Umpolung-Enabled Regio- and Stereoselective Synthesis of N-Containing Molecules from Alkenes and Alkynes

Merging NiH Catalysis and Inner-Sphere Metal-Nitrenoid Transfer for Hydroamidation of Alkynes

(2021) Xiang Lyu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Three-Component 1,2-Carboamidation of Bridged Bicyclic Alkenes via RhIII-Catalyzed Addition of C–H Bonds and Amidating Reagents

(2021) Daniel S. Brandes et al.   ORGANIC LETTERS

Facile Synthesis of Chiral Arylamines, Alkylamines and Amides by Enantioselective NiH‐Catalyzed Hydroamination

(2021) Lingpu Meng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C–H Functionalization Cascades

(2021) Benjamin T. Jones et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed 1,2-Carboamination of Alkenyl Alcohols

(2021) Taeho Kang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Three-Component Syn-Carboamination of Alkenes Using Arylboronic Acids and Dioxazolones

(2021) Sumin Lee et al.   ACS Catalysis

NiH-Catalyzed Hydroamination/Cyclization Cascade: Rapid Access to Quinolines

(2021) Yang Gao et al.   ACS Catalysis

Diastereoselective Three-Component 3,4-Amino Oxygenation of 1,3-Dienes Catalyzed by a Cationic Heptamethylindenyl Rhodium(III) Complex

(2021) Finn Burg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-promoted cobalt-catalyzed radical hydroamination of alkenes

(2020) Xuzhong Shen et al.   Nature Communications

Asymmetric Synthesis of Chiral Chromanes by Copper‐Catalyzed Hydroamination of 2 H ‐Chromenes

(2020) Qingjing Yang et al.   ChemCatChem

Cu‐Catalyzed Reductive gem‐Difunctionalization of Terminal Alkynes via Hydrosilylation/Hydroamination Cascade: Concise Synthesis of α‐Aminosilanes

(2020) Koji Hirano et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and Applications of β Aminoalkylboronic Acid Derivatives

(2020) Xiangyu Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Synthesis of β‐Amino Acid Derivatives Enabled by Ligand‐Controlled Reversal of Hydrocupration Regiochemistry

(2020) Sheng Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Intramolecular Aminoboration of Allenes

(2020) Chun-Hua Yang et al.   ORGANIC LETTERS

Cobalt(III)‐Catalyzed Enantioselective Intermolecular Carboaminations via C‒H Functionalizations

(2020) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NiH-Catalyzed Proximal-Selective Hydroamination of Unactivated Alkenes

(2020) Jinwon Jeon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Asymmetric Hydroamination: A Unified Strategy for the Synthesis of Chiral β-Amino Acid and Its Derivatives

(2020) Ge Zhang et al.   CCS Chemistry

Catalytic Asymmetric Synthesis of α-Arylpyrrolidines and Benzo-fused Nitrogen Heterocycles

(2019) Xi-Jie Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Aza-Heck Cyclizations of N-(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines

(2019) Xiaofeng Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regio- and Enantioselective Formal Hydroamination of Enamines for the Synthesis of 1,2-Diamines

(2019) Lu Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regio- and Enantioselective Synthesis of 1,2-Diamine Derivatives by Copper-Catalyzed Hydroamination

(2019) Saki Ichikawa et al.   ORGANIC LETTERS

Synthesis of α-Trifluoromethylamines by Cu-Catalyzed Regio- and Enantioselective Hydroamination of 1-Trifluoromethylalkenes

(2019) Tatsuaki Takata et al.   ORGANIC LETTERS

Copper-Catalyzed Three-Component Carboamination of Arynes: Expeditious Synthesis of o-Alkynyl Anilines and o-Benzoxazolyl Anilines

(2019) Sheng-Li Niu et al.   ORGANIC LETTERS

Multicomponent Cyclopropane Synthesis Enabled by Cu-Catalyzed Cyclopropene Carbometalation with Organoboron Reagent: Enantioselective Modular Access to Polysubstituted 2-Arylcyclopropylamines

(2019) Zhanyu Li et al.   ORGANIC LETTERS

Enantioselective Synthesis of 4-Aminotetrahydroquinolines via 1,2-Reductive Dearomatization of Quinolines and Copper(I) Hydride-Catalyzed Asymmetric Hydroamination

(2019) Qing-Feng Xu-Xu et al.   ORGANIC LETTERS

Cobalt(III)-Catalyzed Intermolecular Carboamination of Propiolates and Bicyclic Alkenes via Non-Annulative Redox-Neutral Coupling

(2019) Yuelu Zhu et al.   ORGANIC LETTERS

α-Branched amines by catalytic 1,1-addition of C–H bonds and aminating agents to terminal alkenes

(2019) Soham Maity et al.   Nature Catalysis

Asymmetric Synthesis of γ-Amino Alcohols by Copper-Catalyzed Hydroamination

(2019) Saki Ichikawa et al.   ORGANIC LETTERS

Cu-Catalyzed Asymmetric Aminoboration of E-Vinylarenes with pivZPhos as the Ligand

(2019) Linglin Wu et al.   ORGANIC LETTERS

Diastereo- and Enantioselective CuH-Catalyzed Hydroamination of Strained Trisubstituted Alkenes

(2019) Sheng Feng et al.   ACS Catalysis

Cascade CuH-catalysed conversion of alkynes into enantioenriched 1,1-disubstituted products

(2019) De-Wei Gao et al.   Nature Catalysis

A Modified System for the Synthesis of Enantioenriched N -Arylamines through Copper-Catalyzed Hydroamination

(2018) Saki Ichikawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes

(2018) Yujing Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Regio- and Enantioselective Aminoboration of Unactivated Terminal Alkenes

(2018) Kodai Kato et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of α-Aminophosphines by Copper-Catalyzed Regioselective Hydroamination of Vinylphosphines

(2018) Tatsuaki Takata et al.   CHEMISTRY-A EUROPEAN JOURNAL

Remote sp 3 C–H Amination of Alkenes with Nitroarenes

(2018) Jichao Xiao et al.   Chem

A Practical Electrophilic Nitrogen Source for the Synthesis of Chiral Primary Amines by Copper-Catalyzed Hydroamination

(2018) Sheng Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Copper-Catalyzed Hydroamination of Vinylarenes with Anthranils

(2018) Fang Xie et al.   ORGANIC LETTERS

Directed, Nickel-Catalyzed Umpolung 1,2-Carboamination of Alkenyl Carbonyl Compounds

(2018) Vincent A. van der Puyl et al.   ACS Catalysis

CuH-Catalyzed Regioselective Intramolecular Hydroamination for the Synthesis of Alkyl-Substituted Chiral Aziridines

(2017) Haoxuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic intermolecular hydroaminations of unactivated olefins with secondary alkyl amines

(2017) Andrew J. Musacchio et al.   SCIENCE

Recent developments in the use of aza-Heck cyclizations for the synthesis of chiral N-heterocycles

(2017) Nicholas J. Race et al.   Chemical Science

CuH-catalysed hydroamination of arylalkynes with hydroxylamine esters – a computational scrutiny of rival mechanistic pathways

(2017) Sven Tobisch   Chemical Science

Unnatural Amino Acid Synthesis Enabled by the Regioselective Cobalt(III)-Catalyzed Intermolecular Carboamination of Alkenes

(2016) Andreas Lerchen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of β-Boryl-α-Aminosilanes by Copper-Catalyzed Aminoboration of Vinylsilanes

(2016) Kodai Kato et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed regio- and enantioselective aminoboration of alkylidenecyclopropanes: the synthesis of cyclopropane-containing β-aminoalkylboranes

(2016) Han-Chun Jiang et al.   CHEMICAL COMMUNICATIONS

CuH-Catalysed Hydroamination of Styrene with Hydroxylamine Esters: A Coupled Cluster Scrutiny of Mechanistic Pathways

(2016) Sven Tobisch   CHEMISTRY-A EUROPEAN JOURNAL

Transition-Metal-Catalyzed Electrophilic Amination: Application of O -Benzoylhydroxylamines in the Construction of the C−N Bond

(2016) Xu Dong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper-Catalyzed Regioselective Ring-Opening Hydroamination of Methylenecyclopropanes

(2016) Daiki Nishikawa et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Catalysis Powered by Chiral Cyclopentadienyl Ligands

(2016) Christopher G. Newton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Secondary Unsaturated Lactams via an Aza-Heck Reaction

(2016) Scott A. Shuler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols

(2016) Shi-Liang Shi et al.   NATURE

Copper-Catalyzed Regio- and Stereoselective Aminoboration of Alkenylboronates

(2016) Daiki Nishikawa et al.   ORGANIC LETTERS

Synthesis and Reactivity of New Copper(I) Hydride Dimers

(2016) Abraham J. Jordan et al.   ORGANOMETALLICS

Regioselective, Asymmetric Formal Hydroamination of Unactivated Internal Alkenes

(2015) Yumeng Xi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intramolecular Aminoboration of Unfunctionalized Olefins

(2015) Chun-Hua Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper Hydride Catalyzed Hydroamination of Alkenes and Alkynes

(2015) Michael T. Pirnot et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Late Transition Metal-Catalyzed Hydroamination and Hydroamidation

(2015) Liangbin Huang et al.   CHEMICAL REVIEWS

Asymmetric Synthesis of α-Aminoboronic Acid Derivatives by Copper-Catalyzed Enantioselective Hydroamination

(2015) Daiki Nishikawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design of Modified Amine Transfer Reagents Allows the Synthesis of α-Chiral Secondary Amines via CuH-Catalyzed Hydroamination

(2015) Dawen Niu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Controlled Regiodivergent Cu-Catalyzed Aminoboration of Unactivated Terminal Alkenes

(2015) Ryosuke Sakae et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Umpolung Approach to Alkene Carboamination: Palladium Catalyzed 1,2-Amino-Acylation, -Carboxylation, -Arylation, -Vinylation, and -Alkynylation

(2015) Adele Faulkner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Studies on the Rh(III)-Mediated Amido Transfer Process Leading to Robust C–H Amination with a New Type of Amidating Reagent

(2015) Yoonsu Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aminoboration: Addition of B–N σ Bonds across C–C π Bonds

(2015) Eugene Chong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-catalysed syn-carboamination of alkenes via a transient directing group

(2015) Tiffany Piou et al.   NATURE

Nonprecious Metals Catalyzing Hydroamination and C–N Coupling Reactions

(2015) Simona M. Coman et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Practical olefin hydroamination with nitroarenes

(2015) J. Gui et al.   SCIENCE

Catalytic asymmetric hydroamination of unactivated internal olefins to aliphatic amines

(2015) Y. Yang et al.   SCIENCE

Copper-Catalyzed Stereoselective Aminoboration of Bicyclic Alkenes

(2014) Ryosuke Sakae et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of α-Aminosilanes by Copper-Catalyzed Hydroamination of Vinylsilanes

(2014) Nootaree Niljianskul et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective CuH-Catalyzed Anti-Markovnikov Hydroamination of 1,1-Disubstituted Alkenes

(2014) Shaolin Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Diastereo- and Enantioselective Desymmetrization of Cyclopropenes: Synthesis of Cyclopropylboronates

(2014) Alejandro Parra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Intermolecular Hydroamination of Styrenes

(2014) C. Bryan Huehls et al.   ORGANIC LETTERS

Highly Stereoselective Synthesis of (Borylmethyl)cyclopropylamines by Copper-Catalyzed Aminoboration of Methylenecyclopropanes

(2014) Ryosuke Sakae et al.   ORGANIC LETTERS

Copper-Catalyzed Enantioselective Formal Hydroamination of Oxa- and Azabicyclic Alkenes with Hydrosilanes and Hydroxylamines

(2014) Yuya Miki et al.   ORGANIC LETTERS

Recent Advances in Electrophilic Amination Reactions

(2014) Corinne Gosmini et al.   SYNTHESIS-STUTTGART

A Cationic High-Valent Cp*CoIIIComplex for the Catalytic Generation of Nucleophilic Organometallic Species: Directed CH Bond Activation

(2013) Tatsuhiko Yoshino et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Intermolecular Regioselective Hydroamination of Styrenes with Polymethylhydrosiloxane and Hydroxylamines

(2013) Yuya Miki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective and Stereospecific Copper-Catalyzed Aminoboration of Styrenes with Bis(pinacolato)diboron and O-Benzoyl-N,N-dialkylhydroxylamines

(2013) Naoki Matsuda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantio- and Regioselective CuH-Catalyzed Hydroamination of Alkenes

(2013) Shaolin Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Amination of Arylboronates with N,N-Dialkylhydroxylamines

(2012) Naoki Matsuda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Hindered Anilines: Copper-Catalyzed Electrophilic Amination of Aryl Boronic Esters

(2012) Richard P. Rucker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Boron Containing Compounds as Protease Inhibitors

(2012) Reem Smoum et al.   CHEMICAL REVIEWS

Porphyrin-sensitized solar cells

(2012) Lu-Lin Li et al.   CHEMICAL SOCIETY REVIEWS

Organosilicon Molecules with Medicinal Applications

(2012) Annaliese K. Franz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Tertiary Alkyl Amines from Terminal Alkenes: Copper-Catalyzed Amination of Alkyl Boranes

(2012) Richard P. Rucker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Developments in Transition-Metal-Catalyzed Reactions Using Electrophilic Nitrogen Sources

(2011) Elizabeth Jarvo et al.   SYNTHESIS-STUTTGART

Rhodium- and Iridium-Catalyzed Hydroamination of Alkenes

(2010) Kevin D. Hesp et al.   ChemCatChem

Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis

(2010) Tetsuya Satoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cyclizations via Frustrated Lewis Pairs: Lewis Acid Induced Intramolecular Additions of Amines to Olefins and Alkynes

(2010) Tanja Voss et al.   CHEMISTRY-A EUROPEAN JOURNAL

CuH-Catalyzed Reactions

(2008) Carl Deutsch et al.   CHEMICAL REVIEWS

Hydroamination: Direct Addition of Amines to Alkenes and Alkynes

(2008) Thomas E. Müller et al.   CHEMICAL REVIEWS

A Simple, Modular Synthesis of Substituted Pyridines

(2008) Songbai Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY