Long-term culture of SH-SY5Y neuroblastoma cells in the absence of neurotrophins: A novel model of neuronal ageing

Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research

(2021) Rui F. Simões et al.   FOOD AND CHEMICAL TOXICOLOGY

Upregulation of APP endocytosis by neuronal aging drives amyloid-dependent synapse loss

(2021) Tatiana Burrinha et al.   JOURNAL OF CELL SCIENCE

Optimized Protocol for Robust Differentiation of SH‐SY5Y Cells into Neuronal‐like Cells: An in vitro Model of Human Neuronal Cultures

(2020) Jinwoo Jun et al.   FASEB JOURNAL

Neuroprotective actions of leptin facilitated through balancing mitochondrial morphology and improving mitochondrial function

(2020) Ying Cheng et al.   JOURNAL OF NEUROCHEMISTRY

Modeling and Targeting Alzheimer’s Disease With Organoids

(2020) Angelos Papaspyropoulos et al.   Frontiers in Pharmacology

ProNGF and Neurodegeneration in Alzheimer’s Disease

(2019) Margaret Fahnestock et al.   Frontiers in Neuroscience

Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease

(2019) Elizabeta Zaplatic et al.   LIFE SCIENCES

Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease

(2018) Neng Jiang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An in vivo model of functional and vascularized human brain organoids

(2018) Abed AlFatah Mansour et al.   NATURE BIOTECHNOLOGY

Tau protein aggregation is associated with cellular senescence in the brain

(2018) Nicolas Musi et al.   AGING CELL

Hydroxytyrosol butyrate inhibits 6-OHDA-induced apoptosis through activation of the Nrf2/HO-1 axis in SH-SY5Y cells

(2018) Megumi Funakohi-Tago et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Purinergic receptor P2Y6 contributes to 1-methyl-4-phenylpyridinium-induced oxidative stress and cell death in neuronal SH-SY5Y cells

(2017) Yiwei Qian et al.   JOURNAL OF NEUROSCIENCE RESEARCH

An In Vitro Model for Neuroscience: Differentiation of SH-SY5Y Cells into Cells with Morphological and Biochemical Characteristics of Mature Neurons

(2017) Lotta Agholme et al.   JOURNAL OF ALZHEIMERS DISEASE

A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin

(2016) Yasaman Malekizadeh et al.   CEREBRAL CORTEX

Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease

(2016) Xiao-Dong Pan et al.   CHINESE MEDICAL JOURNAL

Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure

(2016) Ahmi Öz et al.   MOLECULAR MEMBRANE BIOLOGY

Generating Late-Onset Human iPSC-Based Disease Models by Inducing Neuronal Age-Related Phenotypes through Telomerase Manipulation

(2016) Elsa Vera et al.   Cell Reports

Iron for proliferation of cell lines and hematopoietic progenitors: Nailing down the intracellular functional iron concentration

(2015) Emmanuel Pourcelot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

(2015) Jerome Mertens et al.   Cell Stem Cell

Protein modification and maintenance systems as biomarkers of ageing

(2015) Valerie Vanhooren et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Cellular senescence in aging and age-related disease: from mechanisms to therapy

(2015) Bennett G Childs et al.   NATURE MEDICINE

Morphological Differentiation Towards Neuronal Phenotype of SH-SY5Y Neuroblastoma Cells by Estradiol, Retinoic Acid and Cholesterol

(2015) Heidi Teppola et al.   NEUROCHEMICAL RESEARCH

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability

(2015) Anna-Claire Devlin et al.   Nature Communications

Analysis of the Catecholaminergic Phenotype in Human SH-SY5Y and BE(2)-M17 Neuroblastoma Cell Lines upon Differentiation

(2015) Roberta Filograna et al.   PLoS One

Cellular senescence and its effector programs

(2014) R. Salama et al.   GENES & DEVELOPMENT

Stem Cells on the Brain: Modeling Neurodevelopmental and Neurodegenerative Diseases Using Human Induced Pluripotent Stem Cells

(2014) Priya Srikanth et al.   JOURNAL OF NEUROGENETICS

Serum-reduced and serum-free media for differentiation of Caco-2 cells

(2014) Simonetta Ferruzza   ALTEX-Alternatives to Animal Experimentation

Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

(2013) Justine D. Miller et al.   Cell Stem Cell

Phenotypic Characterization of Retinoic Acid Differentiated SH-SY5Y Cells by Transcriptional Profiling

(2013) Joanna A. Korecka et al.   PLoS One

Healthy aging: what can we learn from Caenorhabditis elegans?

(2013) A. Torgovnick et al.   ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE

The lipid peroxidation product 4-hydroxy-2-nonenal: Advances in chemistry and analysis

(2013) Corinne M. Spickett   Redox Biology

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

(2012) Diana Jurk et al.   AGING CELL

The promise of induced pluripotent stem cells in research and therapy

(2012) Daisy A. Robinton et al.   NATURE

Induction of human neuronal cells by defined transcription factors

(2011) Zhiping P. Pang et al.   NATURE

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

(2010) Fernanda Martins Lopes et al.   BRAIN RESEARCH

Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells

(2010) Li Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Protective effects of TRH and its analogues against various cytotoxic agents in retinoic acid (RA)-differentiated human neuroblastoma SH-SY5Y cells

(2010) L. Jaworska-Feil et al.   NEUROPEPTIDES

8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis

(2009) ATHANASIOS VALAVANIDIS et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Neuroprotective actions of leptin on central and peripheral neurons in vitro

(2008) G.H. Doherty et al.   NEUROSCIENCE

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research

(2008) Yuen-Ting Cheung et al.   NEUROTOXICOLOGY