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Estrogen Signaling in Alzheimer’s Disease: Molecular Insights and Therapeutic Targets for Alzheimer’s Dementia

(2020) Md. Sahab Uddin et al.   MOLECULAR NEUROBIOLOGY

Gnaq Protects PC12 Cells from Oxidative Damage by Activation of Nrf2 and Inhibition of NF-kB

(2020) Xin Sun et al.   NEUROMOLECULAR MEDICINE

Shenzao jiannao oral liquid, an herbal formula, ameliorates cognitive impairments by rescuing neuronal death and triggering endogenous neurogenesis in AD-like mice induced by a combination of Aβ42 and scopolamine

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Tiao Geng decoction for treating menopausal syndrome exhibits anti-aging effects likely via suppressing ASK1/MKK7/JNK mediated apoptosis in ovariectomized rats

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Protective Effect of Quercetin against H2O2-Induced Oxidative Damage in PC-12 Cells: Comprehensive Analysis of a lncRNA-Associated ceRNA Network

(2020) Zheyu Zhang et al.   Oxidative Medicine and Cellular Longevity

Tiao Geng decoction inhibits tributyltin chloride-induced GT1-7 neuronal apoptosis through ASK1/MKK7/JNK signaling pathway

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Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

(2019) Antonio Cuadrado et al.   NATURE REVIEWS DRUG DISCOVERY

Oxidative Stress: A Key Modulator in Neurodegenerative Diseases

(2019) Anju Singh et al.   MOLECULES

The Role of Estrogen in Brain and Cognitive Aging

(2019) Jason K. Russell et al.   Neurotherapeutics

Shaping the Nrf2-ARE-related pathways in Alzheimer’s and Parkinson’s diseases

(2019) Lígia Fão et al.   AGEING RESEARCH REVIEWS

Protodioscin protects PC12 cells against oxygen and glucose deprivation-induced injury through miR-124/AKT/Nrf2 pathway

(2019) Kun Shu et al.   CELL STRESS & CHAPERONES

Inhibition of HDAC4 Attenuated JNK/c-Jun-Dependent Neuronal Apoptosis and Early Brain Injury Following Subarachnoid Hemorrhage by Transcriptionally Suppressing MKK7

(2019) Liqiang Wu et al.   Frontiers in Cellular Neuroscience

Reasonably activating Nrf2: A long-term, effective and controllable strategy for neurodegenerative diseases

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Involvement of the Nrf2-Keap1 signaling pathway in protection against thallium-induced oxidative stress and mitochondrial dysfunction in primary hippocampal neurons

(2019) Guodong Lin et al.   TOXICOLOGY LETTERS

Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease

(2018) A.I. Duarte et al.   NEUROPHARMACOLOGY

Neuroprotective Effect of Hydrogen Sulfide in Hyperhomocysteinemia Is Mediated Through Antioxidant Action Involving Nrf2

(2018) Mohit Kumar et al.   NEUROMOLECULAR MEDICINE

Vitamin K2 protects PC12 cells against Aβ (1-42) and H2O2-induced apoptosis via p38 MAP kinase pathway

(2018) Elham Hadipour et al.   NUTRITIONAL NEUROSCIENCE

Neurogenic Traditional Chinese Medicine as a Promising Strategy for the Treatment of Alzheimer’s Disease

(2017) Sravan Sreenivasmurthy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective Effect of Quercetin against Oxidative Stress-Induced Cytotoxicity in Rat Pheochromocytoma (PC-12) Cells

(2017) Dengke Bao et al.   MOLECULES

From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

(2017) Avi Ashkenazi et al.   NATURE REVIEWS DRUG DISCOVERY

Resveratrol Attenuates the Cytotoxicity Induced by Amyloid-β1–42 in PC12 Cells by Upregulating Heme Oxygenase-1 via the PI3K/Akt/Nrf2 Pathway

(2017) Yang Hui et al.   NEUROCHEMICAL RESEARCH

Oxidative damage and the pathogenesis of menopause related disturbances and diseases

(2016) Carlo Cervellati et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Neurodegenerative diseases linked to misfolded proteins and their therapeutic approaches: A review

(2016) Hena Khanam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Menopause and Parkinson’s disease. Interaction between estrogens and brain renin-angiotensin system in dopaminergic degeneration

(2016) Jose L. Labandeira-Garcia et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Sex and the development of Alzheimer's disease

(2016) Christian J. Pike   JOURNAL OF NEUROSCIENCE RESEARCH

Alzheimer’s disease, apolipoprotein E and hormone replacement therapy

(2016) H. Depypere et al.   MATURITAS

The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update

(2016) Meng-Chen Lu et al.   MEDICINAL RESEARCH REVIEWS

TCM, brain function and drug space

(2016) Chunping Tang et al.   NATURAL PRODUCT REPORTS

Nrf2–ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

(2016) Izaskun Buendia et al.   PHARMACOLOGY & THERAPEUTICS

Nrf2—a therapeutic target for the treatment of neurodegenerative diseases

(2015) Delinda A. Johnson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective effects of aloperine on neonatal rat primary cultured hippocampal neurons injured by oxygen–glucose deprivation and reperfusion

(2015) Ning-Tian Ma et al.   Journal of Natural Medicines

Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells

(2015) CHUN-HSIANG CHENG et al.   Molecular Medicine Reports

Perimenopause as a neurological transition state

(2015) Roberta D. Brinton et al.   Nature Reviews Endocrinology

Estrogen Effects on Cognitive and Synaptic Health Over the Lifecourse

(2015) Yuko Hara et al.   PHYSIOLOGICAL REVIEWS

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Activation of the Proapoptotic Bcl-2 Protein Bax by a Small Molecule Induces Tumor Cell Apoptosis

(2014) G. Zhao et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular and Chemical Regulation of the Keap1-Nrf2 Signaling Pathway

(2014) Young-Sam Keum et al.   MOLECULES

Nuclear and cytosolic JNK signalling in neurons

(2014) Eleanor T. Coffey   NATURE REVIEWS NEUROSCIENCE

Principles in Redox Signaling: From Chemistry to Functional Significance

(2012) Alberto Bindoli et al.   ANTIOXIDANTS & REDOX SIGNALING

Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive aging

(2012) Siobán D. Harlow et al.   FERTILITY AND STERILITY

Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia

(2012) C. L. Winchester et al.   HUMAN MOLECULAR GENETICS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update

(2012) John M. Kyriakis et al.   PHYSIOLOGICAL REVIEWS

Chinese herb mix Tiáo-Gēng-Tāng possesses antiaging and antioxidative effects and upregulates expression of estrogen receptors alpha and beta in ovariectomized rats

(2011) Lian-wei Xu et al.   BMC Complementary and Alternative Medicine