Quantitative correlative microscopy reveals the ultrastructural distribution of endogenous endosomal proteins

Lysosome biogenesis: Regulation and functions

(2021) Chonglin Yang et al.   JOURNAL OF CELL BIOLOGY

SKIP ‐ HOPS recruits TBC 1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport

(2020) Marlieke LM Jongsma et al.   EMBO JOURNAL

HOPS recognizes each SNARE, assembling ternary trans-complexes for rapid fusion upon engagement with the 4th SNARE

(2020) Hongki Song et al.   eLife

Correlation of fluorescence microscopy, electron microscopy, and NanoSIMS stable isotope imaging on a single tissue section

(2020) Céline Loussert-Fonta et al.   Communications Biology

Lysosomal storage disorders – challenges, concepts and avenues for therapy: beyond rare diseases

(2019) André R. A. Marques et al.   JOURNAL OF CELL SCIENCE

CORVET, CHEVI and HOPS – multisubunit tethers of the endo-lysosomal system in health and disease

(2019) Jan van der Beek et al.   JOURNAL OF CELL SCIENCE

Correlative single-molecule localization microscopy and electron tomography reveals endosome nanoscale domains

(2019) Christian Franke et al.   TRAFFIC

WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling

(2019) Marte Sneeggen et al.   Nature Communications

Visualizing the cellular route of entry of a cystine-knot peptide with Xfect transfection reagent by electron microscopy

(2019) Xinxin Gao et al.   Scientific Reports

ARFRP1 functions upstream of ARL1 and ARL5 to coordinate recruitment of distinct tethering factors to the trans-Golgi network

(2019) Morié Ishida et al.   JOURNAL OF CELL BIOLOGY

Tricalbins Contribute to Cellular Lipid Flux and Form Curved ER-PM Contacts that Are Bridged by Rod-Shaped Structures

(2019) Patrick C. Hoffmann et al.   DEVELOPMENTAL CELL

Lysosomes as dynamic regulators of cell and organismal homeostasis

(2019) Andrea Ballabio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosome trafficking and signaling in health and neurodegenerative diseases

(2018) Pearl P.Y. Lie et al.   NEUROBIOLOGY OF DISEASE

Neuronal lysosomes

(2018) Shawn M. Ferguson   NEUROSCIENCE LETTERS

Single organelle dynamics linked to 3D structure by correlative live-cell imaging and 3D electron microscopy

(2018) Job Fermie et al.   TRAFFIC

Rab GTPase Function in Endosome and Lysosome Biogenesis

(2018) Lars Langemeyer et al.   TRENDS IN CELL BIOLOGY

Advanced Data Acquisition From Electron Microscopes With SerialEM

(2018) David N. Mastronarde   MICROSCOPY AND MICROANALYSIS

To degrade or not to degrade: mechanisms and significance of endocytic recycling

(2018) Peter J. Cullen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sugar and ice: Immunoelectron microscopy using cryosections according to the Tokuyasu method

(2018) Wiebke Möbius et al.   TISSUE & CELL

Lysosomal storage diseases

(2018) Frances M. Platt et al.   Nature Reviews Disease Primers

Autophagy impairment in Parkinson’s disease

(2017) Cansu Karabiyik et al.   Essays in Biochemistry

WDR91 is a Rab7 effector required for neuronal development

(2017) Kai Liu et al.   JOURNAL OF CELL BIOLOGY

The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes

(2017) Rituraj Marwaha et al.   JOURNAL OF CELL BIOLOGY

Automated tilt series alignment and tomographic reconstruction in IMOD

(2017) David N. Mastronarde et al.   JOURNAL OF STRUCTURAL BIOLOGY

Rab GTPases: master regulators that establish the secretory and endocytic pathways

(2017) Suzanne R. Pfeffer   MOLECULAR BIOLOGY OF THE CELL

A tethering complex drives the terminal stage of SNARE-dependent membrane fusion

(2017) Massimo D’Agostino et al.   NATURE

eC-CLEM: flexible multidimensional registration software for correlative microscopies

(2017) Perrine Paul-Gilloteaux et al.   NATURE METHODS

Sec17 (α-SNAP) and an SM-tethering complex regulate the outcome of SNARE zippering in vitro and in vivo

(2017) Matthew L Schwartz et al.   eLife

Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo

(2017) M Meister et al.   Oncogenesis

Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity

(2016) Nicholas A. Bright et al.   CURRENT BIOLOGY

Lysosomes in cancer—living on the edge (of the cell)

(2016) Saara Hämälistö et al.   CURRENT OPINION IN CELL BIOLOGY

An endosomal tether undergoes an entropic collapse to bring vesicles together

(2016) David H. Murray et al.   NATURE

Ultrastructural relationship of the phagophore with surrounding organelles

(2015) Joanna Biazik et al.   Autophagy

APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments

(2015) Inna Kalaidzidis et al.   JOURNAL OF CELL BIOLOGY

Essential role of endocytosis for interleukin-4-receptor-mediated JAK/STAT signalling

(2015) K. Kurgonaite et al.   JOURNAL OF CELL SCIENCE

MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells

(2015) Diego Ploper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrastructural Morphometry Points to a New Role for LAMTOR2 in Regulating the Endo/Lysosomal System

(2015) Georg F. Vogel et al.   TRAFFIC

Antibodies for immunolabeling by light and electron microscopy: not for the faint hearted

(2014) Gareth Griffiths et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The Complex Ultrastructure of the Endolysosomal System

(2014) J. Klumperman et al.   Cold Spring Harbor Perspectives in Biology

Rab GTPase regulation of retromer-mediated cargo export during endosome maturation

(2012) Ting-Ting Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Membrane curvature and its generation by BAR proteins

(2012) Carsten Mim et al.   TRENDS IN BIOCHEMICAL SCIENCES

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Identification of the Switch in Early-to-Late Endosome Transition

(2010) Dmitry Poteryaev et al.   CELL

Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)

(2010) A. Mishra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Phosphoinositide Switch Controls the Maturation and Signaling Properties of APPL Endosomes

(2009) Roberto Zoncu et al.   CELL

Rab7 Regulates Late Endocytic Trafficking Downstream of Multivesicular Body Biogenesis and Cargo Sequestration

(2009) Phillip A. Vanlandingham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning

(2009) Nuno Rocha et al.   JOURNAL OF CELL BIOLOGY

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes

(2009) Takeshi Ohya et al.   NATURE

Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components

(2009) C. Stroupe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trafficking and function of the tetraspanin CD63

(2008) Maaike S. Pols et al.   EXPERIMENTAL CELL RESEARCH

Imaging and imagination: understanding the endo-lysosomal system

(2008) Eline Meel et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7

(2008) Raul Rojas et al.   JOURNAL OF CELL BIOLOGY

SNX1 Defines an Early Endosomal Recycling Exit for Sortilin and Mannose 6-Phosphate Receptors

(2008) Muriel Mari et al.   TRAFFIC

High Data Output and Automated 3D Correlative Light-Electron Microscopy Method

(2008) Giuseppe Vicidomini et al.   TRAFFIC