Endoplasmic Reticulum Stress Contributes to Copper-Induced Pyroptosis via Regulating the IRE1α-XBP1 Pathway in Pig Jejunal Epithelial Cells

Lycopene Ameliorates Di(2-ethylhexyl) Phthalate-Induced Pyroptosis in Spleen via Suppression of Classic Caspase-1/NLRP3 Pathway

(2021) Xue-Yan Dai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

New insights into crosstalk between pyroptosis and autophagy co-induced by molybdenum and cadmium in duck renal tubular epithelial cells

(2021) Caiying Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Copper induces mitochondria-mediated apoptosis via AMPK-mTOR pathway in hypothalamus of Pigs

(2021) Chaiqin Lei et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Arsenic and antimony co-induced nephrotoxicity via autophagy and pyroptosis through ROS-mediated pathway in vivo and in vitro

(2021) Fang Wan et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The ER Chaperones BiP and Grp94 Regulate the Formation of Insulin-Like Growth Factor 2 (IGF2) Oligomers

(2021) Yi Jin et al.   JOURNAL OF MOLECULAR BIOLOGY

Comparison of nanoparticle-selenium, selenium-enriched yeast and sodium selenite on the alleviation of cadmium-induced inflammation via NF-kB/IκB pathway in heart

(2021) Jing Ge et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Crosstalk between ER stress, NLRP3 inflammasome, and inflammation

(2020) Wei Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Mechanism and regulation of pyroptosis-mediated in cancer cell death

(2020) Jianwei Ruan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Selenium prevent cadmium-induced hepatotoxicity through modulation of endoplasmic reticulum-resident selenoproteins and attenuation of endoplasmic reticulum stress

(2020) Cong Zhang et al.   ENVIRONMENTAL POLLUTION

Berberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes

(2020) Yanyan Wang et al.   PLoS One

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

(2020) Mausita Karmakar et al.   Nature Communications

ER Stress Responses: An Emerging Modulator for Innate Immunity

(2020) Giusy Di Conza et al.   Cells

Effects of dose and duration of dietary copper administration on hepatic lipid peroxidation and ultrastructure alteration in piglets’ model

(2020) Yiming Zhang et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Copper induces energy metabolic dysfunction and AMPK-mTOR pathway-mediated autophagy in kidney of broiler chickens

(2020) Jianzhao Liao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Endoplasmic reticulum stress and oxidative stress contribute to neuronal pyroptosis caused by cerebral venous sinus thrombosis in rats: Involvement of TXNIP/peroxynitrite-NLRP3 inflammasome activation

(2020) Rui Ding et al.   NEUROCHEMISTRY INTERNATIONAL

Endoplasmic reticulum stress aggravates copper-induced apoptosis via the PERK/ATF4/CHOP signaling pathway in duck renal tubular epithelial cells

(2020) Xiaoyu Wang et al.   ENVIRONMENTAL POLLUTION

MicroRNA-204-GSDMD interaction regulates pyroptosis of fibroblast-like synoviocytes in ankylosing spondylitis

(2020) Guangxue Gu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation

(2019) Michael A. Wheeler et al.   CELL

Effects of Pulverized Oyster Mushroom (Pleurotus ostreatus ) on Diarrhea Incidence, Growth Performance, Immunity, and Microbial Composition in Piglets

(2019) Seidu Adams et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells

(2019) Xin Chou et al.   ARCHIVES OF TOXICOLOGY

Activation of the endoplasmic reticulum stress response impacts the NOD1 signaling pathway

(2019) Jonathan M. Mendez et al.   INFECTION AND IMMUNITY

Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β

(2019) Aaron Talty et al.   Cell Death & Disease

Effects of copper hydroxychloride and distillers dried grains with solubles on intestinal microbial concentration and apparent ileal and total tract digestibility of energy and nutrients by growing pigs1

(2019) Charmaine D Espinosa et al.   JOURNAL OF ANIMAL SCIENCE

ER Stress Activates the NLRP3 Inflammasome: A Novel Mechanism of Atherosclerosis

(2019) Xinnong Chen et al.   Oxidative Medicine and Cellular Longevity

Pyroptosis: A new frontier in cancer

(2019) Yuan Fang et al.   BIOMEDICINE & PHARMACOTHERAPY

Effects of copper on oxidative stress and autophagy in hypothalamus of broilers

(2019) Jianzhao Liao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR

(2019) Niko Amin-Wetzel et al.   eLife

Autophagy attenuates copper-induced mitochondrial dysfunction by regulating oxidative stress in chicken hepatocytes

(2018) Fan Yang et al.   CHEMOSPHERE

Paeoniflorin prevents endoplasmic reticulum stress-associated inflammation in lipopolysaccharide-stimulated human umbilical vein endothelial cells via the IRE1α/NF-κB signaling pathway

(2018) Juan Chen et al.   Food & Function

Activation of PERK-eIF2α-ATF4-CHOP axis triggered by excessive ER stress contributes to lead-induced nephrotoxicity

(2018) Min-Ge Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The UPR ER : Sensor and Coordinator of Organismal Homeostasis

(2017) Ashley E. Frakes et al.   MOLECULAR CELL

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Gasdermins: Effectors of Pyroptosis

(2017) Stephen B. Kovacs et al.   TRENDS IN CELL BIOLOGY

Endoplasmic reticulum stress and disturbed calcium homeostasis are involved in copper-induced alteration in hepatic lipid metabolism in yellow catfish Pelteobagrus fulvidraco

(2016) Yu-Feng Song et al.   CHEMOSPHERE

IRE1α-XBP1 signaling pathway, a potential therapeutic target in multiple myeloma

(2016) Lin Chen et al.   LEUKEMIA RESEARCH

XBP1: A Pivotal Transcriptional Regulator of Glucose and Lipid Metabolism

(2016) Christina Piperi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells

(2016) Megan M. Robblee et al.   Cell Reports

ER stress: Autophagy induction, inhibition and selection

(2015) Harun-Or Rashid et al.   Autophagy

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

4-PBA prevents pressure overload-induced myocardial hypertrophy and interstitial fibrosis by attenuating endoplasmic reticulum stress

(2015) Tao Luo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effect of dietary copper amount and source on copper metabolism and oxidative stress of weanling pigs in short-term feeding1

(2015) Y. L. Huang et al.   JOURNAL OF ANIMAL SCIENCE

Protective effects of piperine against copper-ascorbate induced toxic injury to goat cardiac mitochondria in vitro

(2014) Mousumi Dutta et al.   Food & Function

Stressed to death – mechanisms of ER stress-induced cell death

(2013) Natalia Sovolyova et al.   BIOLOGICAL CHEMISTRY

IRE1: ER stress sensor and cell fate executor

(2013) Yani Chen et al.   TRENDS IN CELL BIOLOGY

Dual Role of Selected Antioxidants Found in Dietary Supplements: Crossover between Anti- and Pro-Oxidant Activities in the Presence of Copper

(2012) Jun-Jie Yin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL