Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells

NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism

(2018) Wusheng Xiao et al.   ANTIOXIDANTS & REDOX SIGNALING

Liraglutide attenuates NLRP3 inflammasome-dependent pyroptosis via regulating SIRT1/NOX4/ROS pathway in H9c2 cells

(2018) Ao Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Association Between Renal Tubular Dysfunction and Zinc Level in a Chinese Population Environmentally Exposed to Cadmium

(2018) Xiao Chen et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Seawater inhalation induces acute lung injury via ROS generation and the endoplasmic reticulum stress pathway

(2018) Peng‑Cheng Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The association between dietary cadmium exposure and renal dysfunction - the benchmark dose estimation of reference levels: the ChinaCad study

(2018) Xiao Chen et al.   JOURNAL OF APPLIED TOXICOLOGY

Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK–eIF-2α–CHOP pathway in the unfolded protein response

(2018) Xiaomin Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuins in Renal Health and Disease

(2018) Marina Morigi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Gap junctional intercellular communication and endoplasmic reticulum stress regulate chronic cadmium exposure induced apoptosis in HK-2 cells

(2018) Zehe Ge et al.   TOXICOLOGY LETTERS

Activation of Ca2+-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells

(2018) Jie Gu et al.   Scientific Reports

Dietary cadmium exposure assessment in rural areas of Southwest China

(2018) Jiao Huo et al.   PLoS One

SIRT1/HSF1/HSP pathway is essential for exenatide-alleviated, lipid-induced hepatic endoplasmic reticulum stress

(2017) Xiaobin Zheng et al.   HEPATOLOGY

NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages

(2017) Yan-gang Liu et al.   Cell Death & Disease

CdSe/ZnS quantum dots induce hepatocyte pyroptosis and liver inflammation via NLRP3 inflammasome activation

(2016) Yonghui Lu et al.   BIOMATERIALS

SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation

(2016) Alexandre Prola et al.   CELL DEATH AND DIFFERENTIATION

Role of subcellular calcium redistribution in regulating apoptosis and autophagy in cadmium-exposed primary rat proximal tubular cells

(2016) Fei Liu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1βAxis in Microglia

(2016) Da-ming Sui et al.   MEDIATORS OF INFLAMMATION

Cadmium induces NLRP3 inflammasome-dependent pyroptosis in vascular endothelial cells

(2016) Haiyan Chen et al.   TOXICOLOGY LETTERS

The stress response of human proximal tubule cells to cadmium involves up-regulation of haemoxygenase 1 and metallothionein but not cytochrome P450 enzymes

(2016) Kanyarat Boonprasert et al.   TOXICOLOGY LETTERS

Endoplasmic reticulum stress eIF2α–ATF4 pathway-mediated cyclooxygenase-2 induction regulates cadmium-induced autophagy in kidney

(2016) B Luo et al.   Cell Death & Disease

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

SIRT1 suppresses cardiomyocyte apoptosis in diabetic cardiomyopathy: An insight into endoplasmic reticulum stress response mechanism

(2015) Rong Guo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cadmium Transporters in the Kidney and Cadmium-Induced Nephrotoxicity

(2015) Hong Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Silver Nanoparticles Induce Degradation of the Endoplasmic Reticulum Stress Sensor Activating Transcription Factor-6 Leading to Activation of the NLRP-3 Inflammasome

(2015) Jean-Christophe Simard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-1 but Not Caspase-11 Is Required for NLRC4-Mediated Pyroptosis and Restriction of Infection by FlagellatedLegionellaSpecies in Mouse Macrophages and In Vivo

(2015) Daiane M. Cerqueira et al.   JOURNAL OF IMMUNOLOGY

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

ER stress induces NLRP3 inflammasome activation and hepatocyte death

(2015) C Lebeaupin et al.   Cell Death & Disease

RTN1 mediates progression of kidney disease by inducing ER stress

(2015) Ying Fan et al.   Nature Communications

Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes

(2014) Wusheng Xiao et al.   ARCHIVES OF TOXICOLOGY

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

(2014) Alvin Lu et al.   CELL

NLRP3 Inflammasome as a Novel Player in Myocardial Infarction

(2014) Masafumi Takahashi   International Heart Journal

Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activation

(2014) Soo Jin Yang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro

(2014) Pan Guo et al.   TOXICOLOGICAL SCIENCES

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Resveratrol Inhibits Ionising Irradiation-Induced Inflammation in MSCs by Activating SIRT1 and Limiting NLRP-3 Inflammasome Activation

(2013) Yue Fu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypermethylations of RASAL1 and KLOTHO is associated with renal dysfunction in a Chinese population environmentally exposed to cadmium

(2013) Chen Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice

(2012) C. L. Kriss et al.   BLOOD

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

(2012) Alana G. Lerner et al.   Cell Metabolism

The interplay between endoplasmic reticulum stress and inflammation

(2012) Sumaira Z Hasnain et al.   IMMUNOLOGY AND CELL BIOLOGY

Nrf2 activation prevents cadmium-induced acute liver injury

(2012) Kai C. Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Protein Secretion and the Endoplasmic Reticulum

(2012) A. M. Benham   Cold Spring Harbor Perspectives in Biology

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

(2011) H Kato et al.   CELL DEATH AND DIFFERENTIATION

Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells

(2011) Feng-Ming Wang et al.   EXPERIMENTAL HEMATOLOGY

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

(2011) Yu Li et al.   FASEB JOURNAL

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation

(2010) Feng-Ming Wang et al.   BIOCHEMICAL JOURNAL

Role of metallothionein in cadmium traffic and toxicity in kidneys and other mammalian organs

(2010) Ivan Sabolić et al.   BIOMETALS

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

(2010) I. Papandreou et al.   BLOOD

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity

(2010) Anja Wilmes et al.   TOXICOLOGY IN VITRO

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Current status of cadmium as an environmental health problem

(2009) Lars Järup et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metallothionein protection of cadmium toxicity

(2009) Curtis D. Klaassen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

(2008) S. L. Fink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA