Metastatic Prostate Cancer Cells Secrete Methylglyoxal-Derived MG-H1 to Reprogram Human Osteoblasts into a Dedifferentiated, Malignant-like Phenotype: A Possible Novel Player in Prostate Cancer Bone Metastases
出版年份 2021 全文链接
标题
Metastatic Prostate Cancer Cells Secrete Methylglyoxal-Derived MG-H1 to Reprogram Human Osteoblasts into a Dedifferentiated, Malignant-like Phenotype: A Possible Novel Player in Prostate Cancer Bone Metastases
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 19, Pages 10191
出版商
MDPI AG
发表日期
2021-09-27
DOI
10.3390/ijms221910191
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Magic Peptide: Unique Properties of the LRR11 Peptide in the Activation of Leukotriene Synthesis in Human Neutrophils
- (2021) Galina M. Viryasova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting Intercellular Communication in the Bone Microenvironment to Prevent Disseminated Tumor Cell Escape from Dormancy and Bone Metastatic Tumor Growth
- (2021) Lauren M. Kreps et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- AKT in Bone Metastasis of Solid Tumors: A Comprehensive Review
- (2021) Nico Hinz et al. Cancers
- Methylglyoxal-Dependent Glycative Stress Is Prevented by the Natural Antioxidant Oleuropein in Human Dental Pulp Stem Cells through Nrf2/Glo1 Pathway
- (2021) Simona Delle Monache et al. Antioxidants
- Methylglyoxal-Derived Advanced Glycation End Product (AGE4)-Induced Apoptosis Leads to Mitochondrial Dysfunction and Endoplasmic Reticulum Stress through the RAGE/JNK Pathway in Kidney Cells
- (2021) So-Ra Jeong et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Calcein Binding to Assess Mineralization in Hydrogel Microspheres
- (2021) Kristopher White et al. Polymers
- Evolving Castration Resistance and Prostate Specific Membrane Antigen Expression: Implications for Patient Management
- (2021) Katharina Kessel et al. Cancers
- Glyoxalase-1-Dependent Methylglyoxal Depletion Sustains PD-L1 Expression in Metastatic Prostate Cancer Cells: A Novel Mechanism in Cancer Immunosurveillance Escape and a Potential Novel Target to Overcome PD-L1 Blockade Resistance
- (2021) Cinzia Antognelli et al. Cancers
- Role of the bone microenvironment in bone metastasis of malignant tumors - therapeutic implications
- (2020) Xiaoting Ma et al. CELLULAR ONCOLOGY
- The Role of Cancer-Associated Fibroblasts in Prostate Cancer Tumorigenesis
- (2020) Francesco Bonollo et al. Cancers
- Collagen networks within 3D PEG hydrogels support valvular interstitial cell matrix mineralization
- (2020) Megan E. Schroeder et al. Acta Biomaterialia
- Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme
- (2019) Cinzia Antognelli et al. Oxidative Medicine and Cellular Longevity
- Osteonectin regulates the extracellular matrix mineralization of osteoblasts through P38 signaling pathway
- (2019) Yun‐Sen Zhu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Fermented Oyster Extract Promotes Osteoblast Differentiation by Activating the Wnt/β-Catenin Signaling Pathway, Leading to Bone Formation
- (2019) Ilandarage Menu Neelaka Molagoda et al. Biomolecules
- KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease
- (2018) Cinzia Antognelli et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H 2 O 2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis
- (2018) Lorella Marinucci et al. FREE RADICAL BIOLOGY AND MEDICINE
- Glyoxalases in Urological Malignancies
- (2018) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Glyoxalase 1 sustains the metastatic phenotype of prostate cancer cells via EMT control
- (2018) Cinzia Antognelli et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- β1 integrins mediate the BMP2 dependent transcriptional control of osteoblast differentiation and osteogenesis
- (2018) Molly Brunner et al. PLoS One
- RAGE-dependent mitochondria pathway: a novel target of silibinin against apoptosis of osteoblastic cells induced by advanced glycation end products
- (2018) Y. X. Mao et al. Cell Death & Disease
- Comparative Secretome Profiling and Mutant Protein Identification in Metastatic Prostate Cancer Cells by Quantitative Mass Spectrometry-based Proteomics
- (2018) OH KWANG KWON et al. Cancer Genomics & Proteomics
- Cancer Metastases to Bone: Concepts, Mechanisms, and Interactions with Bone Osteoblasts
- (2018) Alison B. Shupp et al. Cancers
- Testosterone and Follicle Stimulating Hormone–Dependent Glyoxalase 1 Up-Regulation Sustains the Viability of Porcine Sertoli Cells through the Control of Hydroimidazolone– and Argpyrimidine-Mediated NF-κB Pathway
- (2018) Cinzia Antognelli et al. AMERICAN JOURNAL OF PATHOLOGY
- Glyoxalase 2 drives tumorigenesis in human prostate cells in a mechanism involving androgen receptor and p53-p21 axis
- (2017) Cinzia Antognelli et al. MOLECULAR CARCINOGENESIS
- Protective effects of honokiol against methylglyoxal-induced osteoblast damage
- (2016) Kwang Sik Suh et al. CHEMICO-BIOLOGICAL INTERACTIONS
- CD44: More than a mere stem cell marker
- (2016) I. Morath et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Glyoxalase 2 Is Involved in Human Prostate Cancer Progression as Part of a Mechanism Driven By PTEN/PI3K/AKT/mTOR Signaling With Involvement of PKM2 and ERα
- (2016) Vincenzo N. Talesa et al. PROSTATE
- Profilin Expression Is Regulated by Bone Morphogenetic Protein (BMP) in Osteoblastic Cells
- (2015) Wanting Lin et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs
- (2014) Jing Xue et al. BIOCHEMISTRY
- Directed migration of mesenchymal cells: where signaling and the cytoskeleton meet
- (2014) James E Bear et al. CURRENT OPINION IN CELL BIOLOGY
- Sequential and Opposing Activities of Wnt and BMP Coordinate Zebrafish Bone Regeneration
- (2014) Scott Stewart et al. Cell Reports
- Role of advanced glycation end products in cellular signaling
- (2014) Christiane Ott et al. Redox Biology
- A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cells
- (2013) Cinzia Antognelli et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Docetaxel and atrasentan versus docetaxel and placebo for men with advanced castration-resistant prostate cancer (SWOG S0421): a randomised phase 3 trial
- (2013) David I Quinn et al. LANCET ONCOLOGY
- Glyoxalase 1−419C>A Variant Is Associated with Oxidative Stress: Implications in Prostate Cancer Progression
- (2013) Cinzia Antognelli et al. PLoS One
- Role of glyoxalase I in the proliferation and apoptosis control of human LNCaP and PC3 prostate cancer cells
- (2012) Cinzia Antognelli et al. PROSTATE
- PSA affects prostate cancer cell invasion in vitro and induces an osteoblastic phenotype in bone in vivo
- (2011) A P Cumming et al. PROSTATE CANCER AND PROSTATIC DISEASES
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