Methylglyoxal-Derived Advanced Glycation End Product (AGE4)-Induced Apoptosis Leads to Mitochondrial Dysfunction and Endoplasmic Reticulum Stress through the RAGE/JNK Pathway in Kidney Cells

Dicarbonyl derived post-translational modifications: chemistry bridging biology and aging-related disease

(2020) Christian Sibbersen et al.   Essays in Biochemistry

Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway

(2020) Yangfang Ding et al.   Oxidative Medicine and Cellular Longevity

Methiothepin mesylate causes apoptosis of human prostate cancer cells by mediating oxidative stress and mitochondrial dysfunction

(2020) Changwon Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Methylglyoxal, a potent inducer of AGEs, connects between diabetes and cancer

(2019) Justine Bellier et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Cadmium-induced apoptosis through reactive oxygen species-mediated mitochondrial oxidative stress and the JNK signaling pathway in TM3 cells, a model of mouse Leydig cells

(2019) Susu Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Baicalin modulates apoptosis via RAGE, MAPK, and AP-1 in vascular endothelial cells during Haemophilus parasuis invasion

(2019) Shulin Fu et al.   Innate Immunity

Relationship Between Oxidative Stress, ER Stress, and Inflammation in Type 2 Diabetes: The Battle Continues

(2019) Burgos-Morón et al.   Journal of Clinical Medicine

Methylglyoxal-derived advanced glycation end products induce matrix metalloproteinases through activation of ERK/JNK/NF-κB pathway in kidney proximal epithelial cells

(2019) So-Ra Jeong et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Effect of Advanced Glycation End Products on the Progression of Alzheimer’s Disease

(2019) Ping-Song Chou et al.   JOURNAL OF ALZHEIMERS DISEASE

Ginsenoside Rg1 attenuates cardiomyocyte apoptosis and inflammation via the TLR4/NF‐kB/NLRP3 pathway

(2019) Man Luo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Methylglyoxal Metabolism and Aging-Related Disease: Moving from Correlation toward Causation

(2019) Rasmus Kold-Christensen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

FOXO1 Mediates Advanced Glycation End Products Induced Mouse Osteocyte-Like MLO-Y4 Cell Apoptosis and Dysfunctions

(2019) Citong Zhang et al.   Journal of Diabetes Research

Advanced Glycation End Products (AGEs) Induce Apoptosis of Fibroblasts by Activation of NLRP3 Inflammasome via Reactive Oxygen Species (ROS) Signaling Pathway

(2019) Jiezhi Dai et al.   MEDICAL SCIENCE MONITOR

Advanced glycation end products promote triple negative breast cancer cells via ERK and NF-κB pathway

(2018) Kyung Jin Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells

(2018) David N. DeHart et al.   BIOCHEMICAL PHARMACOLOGY

Advanced glycation end products in the pathogenesis of chronic kidney disease

(2018) Naila Rabbani et al.   KIDNEY INTERNATIONAL

The multifaceted contributions of mitochondria to cellular metabolism

(2018) Jessica B. Spinelli et al.   NATURE CELL BIOLOGY

Pterostilbene inhibited advanced glycation end products (AGEs)-induced oxidative stress and inflammation by regulation of RAGE/MAPK/NF-κB in RAW264.7 cells

(2018) Wenzhe Yu et al.   Journal of Functional Foods

RAGE-dependent mitochondria pathway: a novel target of silibinin against apoptosis of osteoblastic cells induced by advanced glycation end products

(2018) Y. X. Mao et al.   Cell Death & Disease

Kaempferol mitigates Endoplasmic Reticulum Stress Induced Cell Death by targeting caspase 3/7

(2018) Ahmad Abdullah et al.   Scientific Reports

DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways

(2018) Qinhua Jin et al.   Redox Biology

Biomarkers in Islet Cell Transplantation for Type 1 Diabetes

(2018) Fatimah T. AlRashidi et al.   Current Diabetes Reports

The Role of the Transcription Factor Nuclear Factor-kappa B in Thyroid Autoimmunity and Cancer

(2018) Cesidio Giuliani et al.   Frontiers in Endocrinology

c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD+ cleavage activity to inhibit mitochondrial respiration

(2018) Hitoshi Murata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial division inhibitor-1 potentiates cisplatin-induced apoptosis via the mitochondrial death pathway in cholangiocarcinoma cells

(2018) Ornanong Tusskorn et al.   BIOMEDICINE & PHARMACOTHERAPY

Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway

(2017) Yichi Yu et al.   FREE RADICAL BIOLOGY AND MEDICINE

O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress

(2017) Weiqi Xu et al.   JOURNAL OF HEPATOLOGY

From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

(2017) Avi Ashkenazi et al.   NATURE REVIEWS DRUG DISCOVERY

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Eucalrobusone C suppresses cell proliferation and induces ROS-dependent mitochondrial apoptosis via the p38 MAPK pathway in hepatocellular carcinoma cells

(2017) Kai-Li Jian et al.   PHYTOMEDICINE

Luteolin inhibits cell proliferation and induces cell apoptosis via down-regulation of mitochondrial membrane potential in esophageal carcinoma cells EC1 and KYSE450

(2017) Ping Chen et al.   Oncotarget

XBP1-FoxO1 interaction regulates ER stress-induced autophagy in auditory cells

(2017) Akihiro Kishino et al.   Scientific Reports

Molecular mechanisms of ROS production and oxidative stress in diabetes

(2016) P. Newsholme et al.   BIOCHEMICAL JOURNAL

Diabetic nephropathy in type 1 diabetes: a review of early natural history, pathogenesis, and diagnosis

(2016) Nektaria Papadopoulou-Marketou et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane

(2016) Mark P.A. Luna-Vargas et al.   FEBS Journal

Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane

(2016) Katelyn L. O'Neill et al.   GENES & DEVELOPMENT

Endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation

(2016) Kira Meyerovich et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue

(2016) Zhenjiang Liu et al.   Oncotarget

Oxidative and endoplasmic reticulum stress in β-cell dysfunction in diabetes

(2015) Sumaira Z Hasnain et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

XBP1 mitigates aminoglycoside-induced endoplasmic reticulum stress and neuronal cell death

(2015) N Oishi et al.   Cell Death & Disease

The other sweet face of XBP-1

(2011) Kohjiro Ueki et al.   NATURE MEDICINE