Bisphenol a Induces Autophagy Defects and AIF-Dependent Apoptosis via HO-1 and AMPK to Degenerate N2a Neurons

Activation of autophagic flux via LKB1/AMPK/mTOR axis against xenoestrogen Bisphenol-A exposure in primary rat hepatocytes

(2020) Sumit Kr Anand et al.   FOOD AND CHEMICAL TOXICOLOGY

Intersections between Regulated Cell Death and Autophagy

(2019) Francesco Napoletano et al.   TRENDS IN CELL BIOLOGY

Involvement of AMP-activated protein kinase in neuroinflammation and neurodegeneration in the adult and developing brain

(2019) Mariko Saito et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

AICAR, an AMPK activator, protects against cisplatin-induced acute kidney injury through the JAK/STAT/SOCS pathway

(2019) Bodokhsuren Tsogbadrakh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibited autophagy may contribute to heme toxicity in cardiomyoblast cells

(2019) Alexandra Gyongyosi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dual Role of Autophagy in Diseases of the Central Nervous System

(2019) Tamara Bar-Yosef et al.   Frontiers in Cellular Neuroscience

Bisphenol A co-exposure effects: a key factor in understanding BPA’s complex mechanism and health outcomes

(2019) Manoj Sonavane et al.   CRITICAL REVIEWS IN TOXICOLOGY

Neuro-toxic and reproductive effects of BPA

(2019) Antonietta Santoro et al.   Current Neuropharmacology

Autophagy Modulators: Mechanistic Aspects and Drug Delivery Systems

(2019) Tavakol et al.   Biomolecules

A review on sources and health impacts of bisphenol A

(2019) Anna Abraham et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Low-dose bisphenol A exposure impairs learning and memory ability with alterations of neuromorphology and neurotransmitters in rats

(2019) Haibin Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

(2018) Mario Mauthe et al.   Autophagy

Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway

(2018) Min Gi Jo et al.   MOLECULAR NEUROBIOLOGY

Heme Oxygenase 1 in the Nervous System: Does It Favor Neuronal Cell Survival or Induce Neurodegeneration?

(2018) Mariapaola Nitti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bisphenol A exhibits cytotoxic or genotoxic potential via oxidative stress-associated mitochondrial apoptotic pathway in murine macrophages

(2018) Fu-Mei Huang et al.   FOOD AND CHEMICAL TOXICOLOGY

The heat shock response in neurons and astroglia and its role in neurodegenerative diseases

(2017) Rebecca San Gil et al.   Molecular Neurodegeneration

Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer’s Disease-like Neurotoxicity

(2017) Tingwei Wang et al.   Scientific Reports

p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation

(2016) Wei Jing Liu et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Bisphenol A disrupts glucose transport and neurophysiological role of IR/IRS/AKT/GSK3β axis in the brain of male mice

(2016) Jing Li et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Dynamin-related Protein 1 Inhibition Mitigates Bisphenol A-mediated Alterations in Mitochondrial Dynamics and Neural Stem Cell Proliferation and Differentiation

(2016) Swati Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-Glucose-Derived Oxidative Stress-Dependent Heme Oxygenase-1 Expression from Astrocytes Contributes to the Neuronal Apoptosis

(2016) Chuen-Mao Yang et al.   MOLECULAR NEUROBIOLOGY

Control of adult neurogenesis by programmed cell death in the mammalian brain

(2016) Jae Ryun Ryu et al.   Molecular Brain

Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis

(2015) Chenglong Dong et al.   EXPERIMENTAL CELL RESEARCH

Treadmill exercise activates Nrf2 antioxidant system to protect the nigrostriatal dopaminergic neurons from MPP+ toxicity

(2015) Yi-Hsien Tsou et al.   EXPERIMENTAL NEUROLOGY

Activation of Autophagic Flux against Xenoestrogen Bisphenol-A-induced Hippocampal Neurodegeneration via AMP kinase (AMPK)/Mammalian Target of Rapamycin (mTOR) Pathways

(2015) Swati Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bisphenol-A Mediated Inhibition of Hippocampal Neurogenesis Attenuated by Curcumin via Canonical Wnt Pathway

(2015) Shashi Kant Tiwari et al.   MOLECULAR NEUROBIOLOGY

Neurotherapeutic effects of novel HO-1 inhibitorsin vitroand in a transgenic mouse model of Alzheimer's disease

(2015) Ajay Gupta et al.   JOURNAL OF NEUROCHEMISTRY

The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent

(2014) X. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Inhibitory Effects of Bisphenol-A on Neural Stem Cells Proliferation and Differentiation in the Rat Brain Are Dependent on Wnt/β-Catenin Pathway

(2014) Shashi Kant Tiwari et al.   MOLECULAR NEUROBIOLOGY

Bisphenol A induces oxidative stress-associated DNA damage in INS-1 cells

(2014) Fei Xin et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Gastrodin protects against MPP+-induced oxidative stress by up regulates heme oxygenase-1 expression through p38 MAPK/Nrf2 pathway in human dopaminergic cells

(2014) Genling Jiang et al.   NEUROCHEMISTRY INTERNATIONAL

Heme Oxygenase-1 Prevents Cardiac Dysfunction in Streptozotocin-Diabetic Mice by Reducing Inflammation, Oxidative Stress, Apoptosis and Enhancing Autophagy

(2013) Yanli Zhao et al.   PLoS One

Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy

(2012) Ashlee N. Higdon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Targeting Heme Oxygenase-1 for Neuroprotection and Neuroinflammation in Neurodegenerative Diseases

(2012) Agnieszka Jazwa et al.   CURRENT DRUG TARGETS

Unregulated brain iron deposition in transgenic mice over-expressingHMOX1in the astrocytic compartment

(2012) Wei Song et al.   JOURNAL OF NEUROCHEMISTRY

AMPK inhibitor compound C suppresses cell proliferation by induction of apoptosis and autophagy in human colorectal cancer cells

(2012) Weng-Lang Yang et al.   JOURNAL OF SURGICAL ONCOLOGY

Protective effect of N-acetylcysteine on bisphenol A-induced cognitive dysfunction and oxidative stress in rats

(2011) Seema Jain et al.   FOOD AND CHEMICAL TOXICOLOGY

Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects

(2011) Beverly S. Rubin   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival

(2010) Xiao-ming Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Apoptosis-Inducing Factor: Structure, Function, and Redox Regulation

(2010) Irina F. Sevrioukova   ANTIOXIDANTS & REDOX SIGNALING

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway

(2010) Ljubica Vucicevic et al.   Autophagy

Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A

(2010) Laura N. Vandenberg et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bisphenol A induces endoplasmic reticulum stress-associated apoptosis in mouse non-parenchymal hepatocytes

(2010) Junpei Asahi et al.   LIFE SCIENCES

p62, an autophagy hero or culprit?

(2010) Tor Erik Rusten et al.   NATURE CELL BIOLOGY

Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice

(2010) Yu-Hua Tian et al.   SYNAPSE

Expanding roles for AMP-activated protein kinase in neuronal survival and autophagy

(2009) Jeroen Poels et al.   BIOESSAYS

Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement

(2009) Hyman M. Schipper et al.   JOURNAL OF NEUROCHEMISTRY

Suppression of the JNK Pathway by Induction of a Metabolic Stress Response Prevents Vascular Injury and Dysfunction

(2008) Eberhard Schulz et al.   CIRCULATION