Statistical testing in transcriptomic‐neuroimaging studies: A how‐to and evaluation of methods assessing spatial and gene specificity

Overcoming false-positive gene-category enrichment in the analysis of spatially resolved transcriptomic brain atlas data

(2021) Ben D. Fulcher et al.   Nature Communications

A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease

(2021) Douglas P. Wightman et al.   NATURE GENETICS

The ENIGMA Toolbox: multiscale neural contextualization of multisite neuroimaging datasets

(2021) Sara Larivière et al.   NATURE METHODS

Comparing spatial null models for brain maps

(2021) Ross D. Markello et al.   NEUROIMAGE

A molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems

(2020) Jacob W. Vogel et al.   Nature Communications

Association of Human Supragranular Enriched Gene Expression With Cortical Thickness Patterns in 22q11.2 Deletion Syndrome

(2020) Gil Hoftman et al.   BIOLOGICAL PSYCHIATRY

Generative modeling of brain maps with spatial autocorrelation

(2020) Joshua B. Burt et al.   NEUROIMAGE

Convergent molecular, cellular, and cortical neuroimaging signatures of major depressive disorder

(2020) Kevin M. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

A practical guide to linking brain-wide gene expression and neuroimaging data

(2019) Aurina Arnatkevic̆iūtė et al.   NEUROIMAGE

Identification of common genetic risk variants for autism spectrum disorder

(2019) Jakob Grove et al.   NATURE GENETICS

Brain annotation toolbox: exploring the functional and genetic associations of neuroimaging results

(2019) Zhaowen Liu et al.   BIOINFORMATICS

Multi-scale neuroscience of psychiatric disorders

(2019) Martijn P. van den Heuvel et al.   BIOLOGICAL PSYCHIATRY

Regional transcriptional architecture of Parkinson’s disease pathogenesis and network spread

(2019) Benjamin Freeze et al.   BRAIN

Shared vulnerability for connectome alterations across psychiatric and neurological brain disorders

(2019) Siemon C. de Lange et al.   Nature Human Behaviour

Genetic mapping and evolutionary analysis of human-expanded cognitive networks

(2019) Yongbin Wei et al.   Nature Communications

Effects of APOE -ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease

(2018) Raffaele Cacciaglia et al.   Alzheimers & Dementia

Brain Regions Showing White Matter Loss in Huntington’s Disease Are Enriched for Synaptic and Metabolic Genes

(2018) Peter McColgan et al.   BIOLOGICAL PSYCHIATRY

Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in autism

(2018) Rafael Romero-Garcia et al.   MOLECULAR PSYCHIATRY

Structural covariance networks are coupled to expression of genes enriched in supragranular layers of the human cortex

(2018) Rafael Romero-Garcia et al.   NEUROIMAGE

On testing for spatial correspondence between maps of human brain structure and function

(2018) Aaron F. Alexander-Bloch et al.   NEUROIMAGE

Gene expression links functional networks across cortex and striatum

(2018) Kevin M. Anderson et al.   Nature Communications

Hierarchy of transcriptomic specialization across human cortex captured by structural neuroimaging topography

(2018) Joshua B. Burt et al.   NATURE NEUROSCIENCE

Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure

(2018) Christiaan A. de Leeuw et al.   Nature Communications

Shared and distinct transcriptomic cell types across neocortical areas

(2018) Bosiljka Tasic et al.   NATURE

Comprehensive functional genomic resource and integrative model for the human brain

(2018) Daifeng Wang et al.   SCIENCE

Bridging the Gap between Connectome and Transcriptome

(2018) Alex Fornito et al.   TRENDS IN COGNITIVE SCIENCES

A Spotlight on Bridging Microscale and Macroscale Human Brain Architecture

(2017) Martijn P. van den Heuvel et al.   NEURON

Adult ADHD: Risk Factor for Dementia or Phenotypic Mimic?

(2017) Brandy L. Callahan et al.   Frontiers in Aging Neuroscience

Gene transcription profiles associated with inter-modular hubs and connection distance in human functional magnetic resonance imaging networks

(2016) Petra E. Vértes et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Transcriptional profiles of supragranular-enriched genes associate with corticocortical network architecture in the human brain

(2016) Fenna M. Krienen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Specialization and Flexibility in Human Association Cortex

(2015) B. T. Thomas Yeo et al.   CEREBRAL CORTEX

Correspondence between Resting-State Activity and Brain Gene Expression

(2015) Guang-Zhong Wang et al.   NEURON

Correlated gene expression supports synchronous activity in brain networks

(2015) J. Richiardi et al.   SCIENCE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

A FreeSurfer view of the cortical transcriptome generated from the Allen Human Brain Atlas

(2015) Leon French et al.   Frontiers in Neuroscience

The cis-regulatory effect of an Alzheimer’s disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes

(2014) Colton Linnertz et al.   Alzheimers & Dementia

Interneuron cell types are fit to function

(2014) Adam Kepecs et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Understanding Structural-Functional Relationships in the Human Brain

(2014) Zhijiang Wang et al.   NEUROSCIENTIST

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

The WU-Minn Human Connectome Project: An overview

(2013) David C. Van Essen et al.   NEUROIMAGE

Large-Scale Cellular-Resolution Gene Profiling in Human Neocortex Reveals Species-Specific Molecular Signatures

(2012) Hongkui Zeng et al.   CELL

An anatomically comprehensive atlas of the adult human brain transcriptome

(2012) Michael J. Hawrylycz et al.   NATURE

The organization of the human cerebral cortex estimated by intrinsic functional connectivity

(2011) B. T. Thomas Yeo et al.   JOURNAL OF NEUROPHYSIOLOGY

Mapping the human connectome at multiple scales with diffusion spectrum MRI

(2011) Leila Cammoun et al.   JOURNAL OF NEUROSCIENCE METHODS

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Large-scale automated synthesis of human functional neuroimaging data

(2011) Tal Yarkoni et al.   NATURE METHODS

Association of ApoE and LRP mRNA levels with dementia and AD neuropathology

(2011) Afia Akram et al.   NEUROBIOLOGY OF AGING

Gene expression signature is shared by patients with Alzheimer’s disease and schizophrenia at the superior temporal gyrus

(2010) Y. Horesh et al.   EUROPEAN JOURNAL OF NEUROLOGY

Unbiased average age-appropriate atlases for pediatric studies

(2010) Vladimir Fonov et al.   NEUROIMAGE

Regional aerobic glycolysis in the human brain

(2010) S. Neil Vaishnavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional and Evolutionary Insights into Human Brain Development through Global Transcriptome Analysis

(2009) Matthew B. Johnson et al.   NEURON