Endoplasmic reticulum stress-mediated autophagy activation is involved in cadmium-induced ferroptosis of renal tubular epithelial cells

Cadmium-induced dysfunction of the blood-brain barrier depends on ROS-mediated inhibition of PTPase activity in zebrafish

(2021) Tao Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Arsenite induces ferroptosis in the neuronal cells via activation of ferritinophagy

(2021) Junting Xiao et al.   FOOD AND CHEMICAL TOXICOLOGY

Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells

(2021) Xia Qin et al.   Autophagy

Cadmium exposure impairs pancreatic β-cell function and exaggerates diabetes by disrupting lipid metabolism

(2021) Huihui Hong et al.   ENVIRONMENT INTERNATIONAL

Energy-stress-mediated AMPK activation inhibits ferroptosis

(2020) Hyemin Lee et al.   NATURE CELL BIOLOGY

Ferroptosis involves in intestinal epithelial cell death in ulcerative colitis

(2020) Minyi Xu et al.   Cell Death & Disease

Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer

(2020) Daiha Shin et al.   Redox Biology

Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death

(2020) Changfeng Li et al.   Autophagy

Fenton reaction-independent ferroptosis therapy via glutathione and iron redox couple sequentially triggered lipid peroxide generator

(2020) Yu-Jing He et al.   BIOMATERIALS

Environmental pollutants affecting children's growth and development: Collective results from the MOCEH study, a multi-centric prospective birth cohort in Korea

(2020) Surabhi Shah et al.   ENVIRONMENT INTERNATIONAL

Cadmium induces mitochondrial ROS inactivation of XIAP pathway leading to apoptosis in neuronal cells

(2020) Rui Zhao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Effects of Cadmium Toxicity

(2020) Giuseppe Genchi et al.   International Journal of Environmental Research and Public Health

Mitochondrial redox-driven mitofusin 2 S-glutathionylation promotes neuronal necroptosis via disrupting ER-mitochondria crosstalk in cadmium-induced neurotoxicity

(2020) Lin Che et al.   CHEMOSPHERE

Cadmium exposure and risk of breast cancer: A dose-response meta-analysis of cohort studies

(2020) Tommaso Filippini et al.   ENVIRONMENT INTERNATIONAL

Ferroptosis: molecular mechanisms and health implications

(2020) Daolin Tang et al.   CELL RESEARCH

Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells

(2020) Chang Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Endoplasmic reticulum stress and autophagy contributed to cadmium nephrotoxicity in HK-2 cells and Sprague-Dawley rats

(2020) Jian-Ri Li et al.   FOOD AND CHEMICAL TOXICOLOGY

Environmental exposure to cadmium impairs fetal growth and placental angiogenesis via GCN-2-mediated mitochondrial stress

(2020) Yong-Wei Xiong et al.   JOURNAL OF HAZARDOUS MATERIALS

ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress

(2020) Stephanie Vrijsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental cadmium exposure induces fetal growth restriction via triggering PERK-regulated mitophagy in placental trophoblasts

(2020) Hua-Long Zhu et al.   ENVIRONMENT INTERNATIONAL

Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells

(2020) Qiushuang Zhu et al.   JOURNAL OF HAZARDOUS MATERIALS

Ferroptosis is a type of autophagy-dependent cell death

(2019) Borong Zhou et al.   SEMINARS IN CANCER BIOLOGY

Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms

(2019) Kota Fujiki et al.   CELL DEATH AND DIFFERENTIATION

Autophagy: a potential key contributor to the therapeutic action of mesenchymal stem cells

(2019) Sabrina Ceccariglia et al.   Autophagy

The association between plasma selenium and chronic kidney disease related to lead, cadmium and arsenic exposure in a Taiwanese population

(2019) Chih-Yin Wu et al.   JOURNAL OF HAZARDOUS MATERIALS

A TAZ–ANGPTL4–NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer

(2019) Wen-Hsuan Yang et al.   MOLECULAR CANCER RESEARCH

Cadmium and kidney function: Concentrations, variabilities, and associations across various stages of glomerular function

(2019) Ram B. Jain   ENVIRONMENTAL POLLUTION

Molybdenum and cadmium co-induce oxidative stress and apoptosis through mitochondria-mediated pathway in duck renal tubular epithelial cells

(2019) Chang Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Activation of integrated stress response and disordered iron homeostasis upon combined exposure to cadmium and PCB77

(2019) Lixin Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Arsenic induces pancreatic dysfunction and ferroptosis via mitochondrial ROS-autophagy-lysosomal pathway

(2019) Sen Wei et al.   JOURNAL OF HAZARDOUS MATERIALS

GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues

(2018) Matilde Maiorino et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy

(2018) Jiwei Wang et al.   Autophagy

Endoplasmic Reticulum stress signaling and the pathogenesis of Non-Alcoholic Fatty Liver Disease

(2018) Cynthia Lebeaupin et al.   JOURNAL OF HEPATOLOGY

Ferroptosis-Induced Endoplasmic Reticulum Stress: Cross-talk between Ferroptosis and Apoptosis

(2018) Young-Sun Lee et al.   MOLECULAR CANCER RESEARCH

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

(2018) Xinxin Song et al.   CURRENT BIOLOGY

AKT inhibition-mediated dephosphorylation of TFE3 promotes overactive autophagy independent of MTORC1 in cadmium-exposed bone mesenchymal stem cells

(2018) Huifeng Pi et al.   Autophagy

Lipid storage and lipophagy regulates ferroptosis

(2018) Yuansong Bai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Puerarin reverses cadmium-induced lysosomal dysfunction in primary rat proximal tubular cells via inhibiting Nrf2 pathway

(2018) Li-Yuan Wang et al.   BIOCHEMICAL PHARMACOLOGY

Apoptosis and apoptotic body: disease message and therapeutic target potentials

(2018) Xuebo Xu et al.   BIOSCIENCE REPORTS

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Whole cigarette smoke condensates induce ferroptosis in human bronchial epithelial cells

(2018) Eun-Jung Park et al.   TOXICOLOGY LETTERS

ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner

(2017) D Chen et al.   ONCOGENE

Human renal tubular cells contain CD24/CD133 progenitor cell populations: Implications for tubular regeneration after toxicant induced damage using cadmium as a model

(2017) Swojani Shrestha et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Trehalose protects against cadmium-induced cytotoxicity in primary rat proximal tubular cells via inhibiting apoptosis and restoring autophagic flux

(2017) Xin-Yu Wang et al.   Cell Death & Disease

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

(2017) Yangchun Xie et al.   Cell Reports

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Human exposure to environmental pollutants after a tire landfill fire in Spain: Health risks

(2016) Martí Nadal et al.   ENVIRONMENT INTERNATIONAL

Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A

(2016) Chong Xu et al.   NEUROPHARMACOLOGY

Endoplasmic reticulum stress eIF2α–ATF4 pathway-mediated cyclooxygenase-2 induction regulates cadmium-induced autophagy in kidney

(2016) B Luo et al.   Cell Death & Disease

A Chain Modeling Approach To Estimate the Impact of Soil Cadmium Pollution on Human Dietary Exposure

(2016) EELCO FRANZ et al.   JOURNAL OF FOOD PROTECTION

SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin

(2015) Huifeng Pi et al.   Autophagy

Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

(2015) M Hayano et al.   CELL DEATH AND DIFFERENTIATION

Insight into the oxidative stress induced by lead and/or cadmium in blood, liver and kidneys

(2015) Vesna Matović et al.   FOOD AND CHEMICAL TOXICOLOGY

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

(2014) Scott J Dixon et al.   eLife

Crosstalk between apoptosis, necrosis and autophagy

(2013) Vassiliki Nikoletopoulou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Age-relevant renal effects of cadmium exposure through consumption of home-harvested rice in female Japanese farmers

(2013) Hyogo Horiguchi et al.   ENVIRONMENT INTERNATIONAL

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

Effect of Cadmium on Lipid Peroxidation and on Some Antioxidants in the Liver, Kidneys and Testes of Rats Given Diet Containing Cadmium-polluted Radish Bulbs

(2013) Samir Haouem et al.   Journal of Toxicologic Pathology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes

(2011) Yan-Li Ji et al.   JOURNAL OF PINEAL RESEARCH