Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells

Cellular degradation systems in ferroptosis

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Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death

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Ferroptosis is a type of autophagy-dependent cell death

(2019) Borong Zhou et al.   SEMINARS IN CANCER BIOLOGY

Ferroptosis as a target for protection against cardiomyopathy

(2019) Xuexian Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clockophagy is a novel selective autophagy process favoring ferroptosis

(2019) Minghua Yang et al.   Science Advances

Multiple Mechanisms of Zinc-Mediated Inhibition for the Apoptotic Caspases-3, -6, -7, and -8

(2018) Scott J. Eron et al.   ACS Chemical Biology

Lysosomal deposition of copper oxide nanoparticles triggers HUVEC cells death

(2018) Jun Zhang et al.   BIOMATERIALS

Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells

(2018) Zili Zhang et al.   Autophagy

Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles

(2018) Reza Mohammadinejad et al.   Autophagy

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

(2018) Xinxin Song et al.   CURRENT BIOLOGY

Disruption of the Superoxide Anions-Mitophagy Regulation Axis Mediates Copper Oxide Nanoparticles-Induced Vascular Endothelial Cell Death

(2018) Jun Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial biogenesis and metabolic hyperactivation limits the application of MTT assay in the estimation of radiation induced growth inhibition

(2018) Yogesh Rai et al.   Scientific Reports

Lipid storage and lipophagy regulates ferroptosis

(2018) Yuansong Bai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway

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Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Ferroptosis and Its Role in Diverse Brain Diseases

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Autophagy-dependent release of zinc ions is critical for acute lung injury triggered by zinc oxide nanoparticles

(2018) Xuejun Jiang et al.   Nanotoxicology

DHA inhibits proliferation and induces ferroptosis of leukemia cells through autophagy dependent degradation of ferritin

(2018) Jing Du et al.   FREE RADICAL BIOLOGY AND MEDICINE

The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review

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Zinc oxide nanoparticles harness autophagy to induce cell death in lung epithelial cells

(2017) Jun Zhang et al.   Cell Death & Disease

AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

(2017) Rebecca C. Rabinovitch et al.   Cell Reports

Current recommendations for chelation for transfusion-dependent thalassemia

(2016) Janet L. Kwiatkowski   Annals of the New York Academy of Sciences

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Identification of ACSL4 as a biomarker and contributor of ferroptosis

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells

(2016) Renyu Lin et al.   CANCER LETTERS

Ferroptosis: process and function

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Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

(2016) Sung Eun Kim et al.   Nature Nanotechnology

Zinc-Oxide Nanoparticles Exhibit Genotoxic, Clastogenic, Cytotoxic and Actin Depolymerization Effects by Inducing Oxidative Stress Responses in Macrophages and Adult Mice

(2016) Rashmirekha Pati et al.   TOXICOLOGICAL SCIENCES

NCOA4 Deficiency Impairs Systemic Iron Homeostasis

(2016) Roberto Bellelli et al.   Cell Reports

Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories

(2015) Nicklas Raun Jacobsen et al.   FOOD AND CHEMICAL TOXICOLOGY

Biological reactivity of zinc oxide nanoparticles with mammalian test systems: an overview

(2015) Shruti R Saptarshi et al.   Nanomedicine

Genotoxic effects of zinc oxide nanoparticles

(2015) Julia Heim et al.   Nanoscale

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

(2015) Joseph D Mancias et al.   eLife

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

(2014) Rachid Skouta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

(2014) William E. Dowdle et al.   NATURE CELL BIOLOGY

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

ZnO Nanoparticles Applied to Bioimaging and Drug Delivery

(2013) Huan-Ming Xiong   ADVANCED MATERIALS

Biomedical Applications of Zinc Oxide Nanomaterials

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Computational classification of mitochondrial shapes reflects stress and redox state

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Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes

(2012) Ruth M. Mackenzie et al.   CLINICAL SCIENCE

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Zinc Oxide Nanoparticles Interfere With Zinc Ion Homeostasis to Cause Cytotoxicity

(2011) Yi-Yun Kao et al.   TOXICOLOGICAL SCIENCES

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

Flow cytometry measurement of the labile iron pool in human hematopoietic cells

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