Emerging roles for IL-6 family cytokines as positive and negative regulators of ectopic lymphoid structures
出版年份 2021 全文链接
标题
Emerging roles for IL-6 family cytokines as positive and negative regulators of ectopic lymphoid structures
作者
关键词
Interleukin-6, Interleukin-11, Interleukin-27, Oncostatin-M, Leukaemia inhibitory factor, Ectopic Lymphoid Structures, Tertiary Lymphoid Structures
出版物
CYTOKINE
Volume 146, Issue -, Pages 155650
出版商
Elsevier BV
发表日期
2021-08-01
DOI
10.1016/j.cyto.2021.155650
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Therapeutic IL-6 trans-signalling inhibition by olamkicept (sgp130Fc) in patients with active inflammatory bowel disease
- (2021) Stefan Schreiber et al. GASTROENTEROLOGY
- STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment
- (2021) Manoj Chelvanambi et al. Journal for ImmunoTherapy of Cancer
- B cells are associated with survival and immunotherapy response in sarcoma
- (2020) Florent Petitprez et al. NATURE
- Tertiary lymphoid structures improve immunotherapy and survival in melanoma
- (2020) Rita Cabrita et al. NATURE
- B cells and tertiary lymphoid structures promote immunotherapy response
- (2020) Beth A. Helmink et al. NATURE
- Structural Understanding of Interleukin 6 Family Cytokine Signaling and Targeted Therapies: Focus on Interleukin 11
- (2020) Riley D. Metcalfe et al. Frontiers in Immunology
- Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren’s syndrome with ectopic germinal centres and MALT lymphoma
- (2020) Elena Pontarini et al. ANNALS OF THE RHEUMATIC DISEASES
- Anti-IL-17A treatment reduces serum inflammatory, angiogenic and tissue remodeling biomarkers accompanied by less synovial high endothelial venules in peripheral spondyloarthritis
- (2020) Merlijn H. Kaaij et al. Scientific Reports
- Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells
- (2019) Jason P. Twohig et al. NATURE IMMUNOLOGY
- Type I interferon induces CXCL13 to support ectopic germinal center formation
- (2019) Alice E. Denton et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IDO1 inhibition potentiates vaccine-induced immunity against pancreatic adenocarcinoma
- (2019) Alex B. Blair et al. JOURNAL OF CLINICAL INVESTIGATION
- Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity
- (2019) Mattias N.D. Svensson et al. JOURNAL OF CLINICAL INVESTIGATION
- Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients
- (2019) Frances Humby et al. ANNALS OF THE RHEUMATIC DISEASES
- T-Cell–Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities
- (2019) Florian Wiede et al. DIABETES
- Coordination of Immune-Stroma Crosstalk by IL-6 Family Cytokines
- (2019) Nathaniel R. West Frontiers in Immunology
- Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
- (2019) Benjamin Ng et al. Science Translational Medicine
- Features of ectopic lymphoid-like structures in human uveitis
- (2019) Simon J. Epps et al. EXPERIMENTAL EYE RESEARCH
- In vivo affinity and target engagement in skin and blood in a first-time-in-human study of an anti-oncostatin M monoclonal antibody
- (2018) Juliet Reid et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- IL-27: a double agent in the IL-6 family
- (2018) G. W. Jones et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development
- (2018) David G. Hill et al. INTERNATIONAL JOURNAL OF CANCER
- Peribronchial tertiary lymphoid structures persist after rituximab therapy in patients with cystic fibrosis
- (2018) Lucile Regard et al. JOURNAL OF CLINICAL PATHOLOGY
- Atherogenic dyslipidemia promotes autoimmune follicular helper T cell responses via IL-27
- (2018) Heeju Ryu et al. NATURE IMMUNOLOGY
- Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis
- (2018) Rakeshchandra R. Meka et al. JOURNAL OF CONTROLLED RELEASE
- Induction and transcriptional regulation of the co-inhibitory gene module in T cells
- (2018) Norio Chihara et al. NATURE
- Soluble gp130 prevents interleukin-6 and interleukin-11 cluster signaling but not intracellular autocrine responses
- (2018) Larissa Lamertz et al. Science Signaling
- Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators
- (2017) Hung N. Nguyen et al. IMMUNITY
- Dual Roles of IL-27 in Cancer Biology and Immunotherapy
- (2017) Marina Fabbi et al. MEDIATORS OF INFLAMMATION
- IL11 is a crucial determinant of cardiovascular fibrosis
- (2017) Sebastian Schafer et al. NATURE
- Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease
- (2017) Nathaniel R West et al. NATURE MEDICINE
- Ectopic lymphoid neogenesis in rheumatic autoimmune diseases
- (2017) Michele Bombardieri et al. Nature Reviews Rheumatology
- Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling
- (2017) D J Junk et al. ONCOGENE
- Treg-specific IL-27Rα deletion uncovers a key role for IL-27 in Treg function to control autoimmunity
- (2017) Jeongsu Do et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interleukin-6 Family Cytokines
- (2017) Stefan Rose-John Cold Spring Harbor Perspectives in Biology
- IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression
- (2017) Giacomo Casella et al. Scientific Reports
- Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis
- (2017) Ehab A. Ayaub et al. Scientific Reports
- Targeting Interleukin-11 Receptor- Impairs Human Endometrial Cancer Cell Proliferation and Invasion In Vitro and Reduces Tumor Growth and Metastasis In Vivo
- (2016) A. L. Winship et al. MOLECULAR CANCER THERAPEUTICS
- Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells
- (2016) Sylvia Heink et al. NATURE IMMUNOLOGY
- Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease
- (2016) René Pfeifle et al. NATURE IMMUNOLOGY
- Proteolytic Cleavage Governs Interleukin-11 Trans-signaling
- (2016) Juliane Lokau et al. Cell Reports
- Understanding Immune Cells in Tertiary Lymphoid Organ Development: It Is All Starting to Come Together
- (2016) Gareth W. Jones et al. Frontiers in Immunology
- Immune contexture and histological response after neoadjuvant chemotherapy predict clinical outcome of lung cancer patients
- (2016) Romain Remark et al. OncoImmunology
- Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs
- (2015) Elisa Corsiero et al. ANNALS OF THE RHEUMATIC DISEASES
- Stromal Cells in Chronic Inflammation and Tertiary Lymphoid Organ Formation
- (2015) Christopher D. Buckley et al. Annual Review of Immunology
- The Immunobiology of Interleukin-27
- (2015) Hiroki Yoshida et al. Annual Review of Immunology
- Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer
- (2015) N Hiraoka et al. BRITISH JOURNAL OF CANCER
- Emerging roles for IL-11 signaling in cancer development and progression: Focus on breast cancer
- (2015) Cameron N. Johnstone et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Interleukin 35: Critical regulator of immunity and lymphocyte-mediated diseases
- (2015) Charles E. Egwuagu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Oncostatin M and interleukin-31: Cytokines, receptors, signal transduction and physiology
- (2015) Heike M. Hermanns CYTOKINE & GROWTH FACTOR REVIEWS
- Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors
- (2015) Desheng Hu et al. IMMUNITY
- Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses
- (2015) Nikhil S. Joshi et al. IMMUNITY
- Ectopic lymphoid follicles: inducible centres for generating antigen-specific immune responses within tissues
- (2015) Gareth W. Jones et al. IMMUNOLOGY
- Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis
- (2015) Gareth W. Jones et al. JOURNAL OF EXPERIMENTAL MEDICINE
- An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell–suppressive function and therapeutic efficacy
- (2015) J-s Do et al. Mucosal Immunology
- IL-6 as a keystone cytokine in health and disease
- (2015) Christopher A Hunter et al. NATURE IMMUNOLOGY
- Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma
- (2015) Shlomi Finkin et al. NATURE IMMUNOLOGY
- Ectopic lymphoid neogenesis is strongly associated with activation of the IL-23 pathway in rheumatoid synovitis
- (2015) Juan D. Cañete et al. ARTHRITIS RESEARCH & THERAPY
- Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity
- (2015) J. David Peske et al. Nature Communications
- Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts
- (2015) Jean Albrengues et al. Nature Communications
- An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction
- (2015) Chen Zhu et al. Nature Communications
- Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma
- (2015) Giovanni Francesco Castino et al. OncoImmunology
- Tumor infiltration by Tbet+ effector T cells and CD20+ B cells is associated with survival in gastric cancer patients
- (2015) Audrey Hennequin et al. OncoImmunology
- Targeting IL-11 signaling in colon cancer
- (2015) Matthias Ernst et al. Oncotarget
- Presence of B Cells in Tertiary Lymphoid Structures Is Associated with a Protective Immunity in Patients with Lung Cancer
- (2014) Claire Germain et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- CLEC-2 is required for development and maintenance of lymph nodes
- (2014) C. Benezech et al. BLOOD
- Occurrence of Tertiary Lymphoid Tissue Is Associated with T-Cell Infiltration and Predicts Better Prognosis in Early-Stage Colorectal Cancers
- (2014) G. Di Caro et al. CLINICAL CANCER RESEARCH
- Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation
- (2014) Ceri A. Fielding et al. IMMUNITY
- Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjögren's syndrome
- (2014) Ya-Zhuo Gong et al. JOURNAL OF AUTOIMMUNITY
- LIF/STAT3/SOCS3 Signaling Pathway in Murine Bone Marrow Stromal Cells Suppresses Osteoblast Differentiation
- (2014) Kenta Matsushita et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- IL-17–induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs
- (2014) Henrike Fleige et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Clinicopathological Correlations of Podoplanin (gp38) Expression in Rheumatoid Synovium and Its Potential Contribution to Fibroblast Platelet Crosstalk
- (2014) Manuel J. Del Rey et al. PLoS One
- Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics
- (2014) Glynn Dennis et al. ARTHRITIS RESEARCH & THERAPY
- LIF Mediates Proinvasive Activation of Stromal Fibroblasts in Cancer
- (2014) Jean Albrengues et al. Cell Reports
- Implication of Epstein-Barr Virus Infection in Disease-Specific Autoreactive B Cell Activation in Ectopic Lymphoid Structures of Sjögren's Syndrome
- (2014) Cristina Croia et al. Arthritis & Rheumatology
- Antibody-Secreting Cell Specificity in Labial Salivary Glands Reflects the Clinical Presentation and Serology in Patients With Sjögren's Syndrome
- (2014) Jacen S. Maier-Moore et al. Arthritis & Rheumatology
- Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation
- (2014) E. R. Lutz et al. Cancer Immunology Research
- Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically
- (2013) Tracy L. Putoczki et al. CANCER CELL
- Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells
- (2013) J. Goc et al. CANCER RESEARCH
- Characteristics and significance of colorectal cancer associated lymphoid reaction
- (2013) Juha P. Väyrynen et al. INTERNATIONAL JOURNAL OF CANCER
- CD4+ follicular helper T cell infiltration predicts breast cancer survival
- (2013) Chunyan Gu-Trantien et al. JOURNAL OF CLINICAL INVESTIGATION
- Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses
- (2013) Keiji Hirota et al. NATURE IMMUNOLOGY
- Safety, tolerability, pharmacokinetics and pharmacodynamics of an anti- oncostatin M monoclonal antibody in rheumatoid arthritis: results from phase II randomized, placebo-controlled trials
- (2013) Ernest H Choy et al. ARTHRITIS RESEARCH & THERAPY
- STAT3-Driven Upregulation of TLR2 Promotes Gastric Tumorigenesis Independent of Tumor Inflammation
- (2012) Hazel Tye et al. CANCER CELL
- Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases
- (2012) Arcadi Cipponi et al. CANCER RESEARCH
- CD20+ Tumor-Infiltrating Lymphocytes Have an Atypical CD27- Memory Phenotype and Together with CD8+ T Cells Promote Favorable Prognosis in Ovarian Cancer
- (2012) J. S. Nielsen et al. CLINICAL CANCER RESEARCH
- A role for Th17 cells in the regulation of tertiary lymphoid follicles
- (2012) Jane L. Grogan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology
- (2012) Aisling O’Hara Hall et al. IMMUNITY
- Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1
- (2012) Kiyoshi Hirahara et al. IMMUNITY
- IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6
- (2012) Stefan Rose-John International Journal of Biological Sciences
- Novel IL27p28/IL12p40 Cytokine Suppressed Experimental Autoimmune Uveitis by Inhibiting Autoreactive Th1/Th17 Cells and Promoting Expansion of Regulatory T Cells
- (2012) Ren-Xi Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells
- (2012) Tom A. Barr et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Gene therapy using IL-27 ameliorates Sjögren's syndrome-like autoimmune exocrinopathy
- (2012) Byung Lee et al. ARTHRITIS RESEARCH & THERAPY
- Local expression of interleukin-27 ameliorates collagen-induced arthritis
- (2011) Sarah R. Pickens et al. ARTHRITIS AND RHEUMATISM
- Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis
- (2011) Laura Lovato et al. BRAIN
- Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis
- (2011) Owain W. Howell et al. BRAIN
- Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer
- (2011) L. Martinet et al. CANCER RESEARCH
- Treg versus Th17 lymphocyte lineages are cross-regulated by LIF versus IL-6
- (2011) Wenda Gao et al. CELL CYCLE
- LIF in the regulation of T-cell fate and as a potential therapeutic
- (2011) S M Metcalfe GENES AND IMMUNITY
- Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation
- (2011) Anneli Peters et al. IMMUNITY
- Leukemia Inhibitory Factor Inhibits T Helper 17 Cell Differentiation and Confers Treatment Effects of Neural Progenitor Cell Therapy in Autoimmune Disease
- (2011) Wei Cao et al. IMMUNITY
- Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
- (2011) Simon A. Jones et al. JOURNAL OF CLINICAL INVESTIGATION
- The development of inducible bronchus-associated lymphoid tissue depends on IL-17
- (2011) Javier Rangel-Moreno et al. NATURE IMMUNOLOGY
- Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection
- (2011) J. A. Harker et al. SCIENCE
- ADAM17: a molecular switch to control inflammation and tissue regeneration
- (2011) Jürgen Scheller et al. TRENDS IN IMMUNOLOGY
- Long-Term Allograft Tolerance Is Characterized by the Accumulation of B Cells Exhibiting an Inhibited Profile
- (2010) L. Le Texier et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Tertiary lymphoid organs in renal allografts can be associated with donor-specific tolerance rather than rejection
- (2010) Kathryn Brown et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice
- (2010) Emma C. Walker et al. JOURNAL OF CLINICAL INVESTIGATION
- IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells
- (2010) Marcel Batten et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation
- (2010) Susann Winter et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- A role for IL-27p28 as an antagonist of gp130-mediated signaling
- (2010) Jason S Stumhofer et al. NATURE IMMUNOLOGY
- Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus–infected mice
- (2009) Corine H. GeurtsvanKessel et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells
- (2009) Oliver Dienz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
- (2009) Thomas Duhen et al. NATURE IMMUNOLOGY
- B Cell Survival in Intragraft Tertiary Lymphoid Organs After Rituximab Therapy
- (2009) Olivier Thaunat et al. TRANSPLANTATION
- Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis
- (2009) Kathrin Schwager et al. ARTHRITIS RESEARCH & THERAPY
- Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium
- (2009) Frances Humby et al. PLOS MEDICINE
- Endogenous IL-11 Signaling Is Essential in Th2- and IL-13–Induced Inflammation and Mucus Production
- (2008) Chun Geun Lee et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Interleukin 27 attenuates collagen-induced arthritis
- (2008) W Niedbala et al. ANNALS OF THE RHEUMATIC DISEASES
- Clinical significance of synovial lymphoid neogenesis and its reversal after anti-tumour necrosis factor therapy in rheumatoid arthritis
- (2008) J D Canete et al. ANNALS OF THE RHEUMATIC DISEASES
- Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
- (2008) Hideki Ogura et al. IMMUNITY
- Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures
- (2008) Marie-Caroline Dieu-Nosjean et al. JOURNAL OF CLINICAL ONCOLOGY
- IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells
- (2008) T. Korn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interleukin-6 Is Crucial for Recall of Influenza-Specific Memory CD4+ T Cells
- (2008) Maria Paula Longhi et al. PLoS Pathogens
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