Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs

Association between anti-Porphyromonas gingivalis or anti-α-enolase antibody and severity of periodontitis or rheumatoid arthritis (RA) disease activity in RA

(2015) Joo Youn Lee et al.   BMC MUSCULOSKELETAL DISORDERS

Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis

(2015) Heidi Kokkonen et al.   ARTHRITIS RESEARCH & THERAPY

Accumulation of Self-Reactive Naïve and Memory B Cell Reveals Sequential Defects in B Cell Tolerance Checkpoints in Sjögren’s Syndrome

(2014) Elisa Corsiero et al.   PLoS One

Development of anti-citrullinated protein antibody and rheumatoid factor isotypes prior to the onset of rheumatoid arthritis

(2014) Wouter H Bos et al.   ARTHRITIS RESEARCH & THERAPY

Implication of Epstein-Barr Virus Infection in Disease-Specific Autoreactive B Cell Activation in Ectopic Lymphoid Structures of Sjögren's Syndrome

(2014) Cristina Croia et al.   Arthritis & Rheumatology

Antibodies from patients with rheumatoid arthritis target citrullinated histone 4 contained in neutrophils extracellular traps

(2013) Federico Pratesi et al.   ANNALS OF THE RHEUMATIC DISEASES

Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients

(2013) S Kelly et al.   ANNALS OF THE RHEUMATIC DISEASES

Ectopic germinal centers, BAFF and anti-B-cell therapy in myasthenia gravis

(2013) Sonia Berrih-Aknin et al.   AUTOIMMUNITY REVIEWS

New learnings on the pathophysiology of RA from synovial biopsies

(2013) Costantino Pitzalis et al.   CURRENT OPINION IN RHEUMATOLOGY

Adaptive immunity in rheumatoid arthritis

(2013) Lars Klareskog et al.   CURRENT OPINION IN RHEUMATOLOGY

Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

(2013) Khaled Amara et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process

(2013) C. Farrera et al.   JOURNAL OF IMMUNOLOGY

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Epstein–Barr virus persistence and infection of autoreactive plasma cells in synovial lymphoid structures in rheumatoid arthritis

(2012) Cristina Croia et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

(2012) S. Sangaletti et al.   BLOOD

Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

(2012) Jeremy Sokolove et al.   PLoS One

Immunoglobulin Analysis Tool: A Novel Tool for the Analysis of Human and Mouse Heavy and Light Chain Transcripts

(2012) Tobias Rogosch et al.   Frontiers in Immunology

A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells

(2011) M. Bombardieri et al.   ANNALS OF THE RHEUMATIC DISEASES

Synovial fibroblasts promote immunoglobulin class switching by a mechanism involving BAFF

(2011) Ghada Alsaleh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

V-region gene analysis of locally defined synovial B and plasma cells reveals selected B cell expansion and accumulation of plasma cell clones in rheumatoid arthritis

(2010) Tobias Scheel et al.   ARTHRITIS AND RHEUMATISM

Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis

(2010) Natalia Wegner et al.   ARTHRITIS AND RHEUMATISM

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling

(2009) Antonio Manzo et al.   IMMUNOLOGICAL REVIEWS

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

(2009) Frances Humby et al.   PLOS MEDICINE

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

(2007) Thomas Tiller et al.   JOURNAL OF IMMUNOLOGICAL METHODS