标题
Roles of MET in human cancer
作者
关键词
MET, Cancer, Carcinogenesis mechanism, HGF-MET axis
出版物
CLINICA CHIMICA ACTA
Volume 525, Issue -, Pages 69-83
出版商
Elsevier BV
发表日期
2021-12-21
DOI
10.1016/j.cca.2021.12.017
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Colorectal cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Case of Hereditary Papillary Renal Cell Carcinoma Type I in a Patient With a Germline MET Mutation in Russia
- (2020) Dmitry S. Mikhaylenko et al. Frontiers in Oncology
- The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma
- (2020) Haiyu Wang et al. Frontiers in Cell and Developmental Biology
- Surgical Treatments of Hepatobiliary Cancers
- (2020) Ganesh Gunasekaran et al. HEPATOLOGY
- Profiling global cancer incidence and mortality by socioeconomic development
- (2020) Joannie Lortet‐Tieulent et al. INTERNATIONAL JOURNAL OF CANCER
- Exosome-Delivered c-Met siRNA Could Reverse Chemoresistance to Cisplatin in Gastric Cancer
- (2020) Qiumo Zhang et al. International Journal of Nanomedicine
- The Role of MET Inhibitor Therapies in the Treatment of Advanced Non-Small Cell Lung Cancer
- (2020) Ramon Andrade De Mello et al. Journal of Clinical Medicine
- The burden of gastric cancer
- (2020) Chisato Hamashima Annals of Translational Medicine
- Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells
- (2019) Omidreza Firuzi et al. Cancers
- MET in glioma: signaling pathways and targeted therapies
- (2019) Fangling Cheng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Endostar regulates EMT, migration and invasion of lung cancer cells through the HGF-Met pathway
- (2019) Yuyao Shen et al. MOLECULAR AND CELLULAR PROBES
- c-MET Overexpression in Colorectal Cancer: A Poor Prognostic Factor for Survival
- (2018) Su Jin Lee et al. Clinical Colorectal Cancer
- MET in gastric cancer with liver metastasis: The relationship between MET amplification and Met overexpression in primary stomach tumors and liver metastasis
- (2018) Han S. Kim et al. JOURNAL OF SURGICAL ONCOLOGY
- Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway
- (2018) Syue-Ting Chen et al. ONCOGENE
- Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases: A systematic review of the current evidence
- (2018) Diamantis I. Tsilimigras et al. SURGICAL ONCOLOGY-OXFORD
- Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018
- (2018) J. Ferlay et al. EUROPEAN JOURNAL OF CANCER
- Status of Agents Targeting the HGF/c-Met Axis in Lung Cancer
- (2018) Oshin Miranda et al. Cancers
- LBA52Results of the GEOMETRY mono-1 phase II study for evaluation of the MET inhibitor capmatinib (INC280) in patients (pts) with METΔex14 mutated advanced non-small cell lung cancer (NSCLC)
- (2018) J Wolf et al. ANNALS OF ONCOLOGY
- Update on clinical gene therapy for hemophilia
- (2018) George Q. Perrin et al. BLOOD
- Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor
- (2018) Huimin Hu et al. CELL
- Molecular Diagnostic Assays and Clinicopathologic Implications of MET Exon 14 Skipping Mutation in Non–small-cell Lung Cancer
- (2018) Eun Kyung Kim et al. Clinical Lung Cancer
- Clinical and prognostic value of the C-Met/HGF signaling pathway in cervical cancer
- (2017) Nadia Boromand et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Emergence of Preexisting MET Y1230C Mutation as a Resistance Mechanism to Crizotinib in NSCLC with MET Exon 14 Skipping
- (2017) Sai-Hong Ignatius Ou et al. Journal of Thoracic Oncology
- Targeting MET in Lung Cancer: Will Expectations Finally Be MET?
- (2017) Alexander Drilon et al. Journal of Thoracic Oncology
- MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale
- (2017) Ravi Salgia MOLECULAR CANCER THERAPEUTICS
- Targeting c-MET in gastrointestinal tumours: rationale, opportunities and challenges
- (2017) Conor A. Bradley et al. Nature Reviews Clinical Oncology
- The c-Met receptor: Implication for targeted therapies in colorectal cancer
- (2017) Elmira Safaie Qamsari et al. TUMOR BIOLOGY
- Clinicopathological and prognostic significance of c-Met overexpression in breast cancer
- (2017) Xixi Zhao et al. Oncotarget
- The Therapeutic Targeting of HGF/c-Met Signaling in Hepatocellular Carcinoma: Alternative Approaches
- (2017) Chi-Tan Hu et al. Cancers
- HGF/Met Signaling in Cancer Invasion: The Impact on Cytoskeleton Remodeling
- (2017) Chuan Xiang et al. Cancers
- Adenocarcinomas on the Rise — Does it Influence Survival from Oesophageal Cancer?
- (2017) M. A. Goscinski et al. Scandinavian Journal of Surgery
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- HGF/Met Signaling in Head and Neck Cancer: Impact on the Tumor Microenvironment
- (2016) Stefan Hartmann et al. CLINICAL CANCER RESEARCH
- Diagnosis and Prognostic Significance of c-Met in Cervical Cancer: A Meta-Analysis
- (2016) Jifeng Peng et al. DISEASE MARKERS
- The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma
- (2016) Ichiro Fukumoto et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Exosomes: novel implications in diagnosis and treatment of gastrointestinal cancer
- (2016) Mohammad Rahbari et al. LANGENBECKS ARCHIVES OF SURGERY
- Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma
- (2016) NEW ENGLAND JOURNAL OF MEDICINE
- Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein
- (2015) Anna C. Navis et al. ACTA NEUROPATHOLOGICA
- Searching for targets for the systemic therapy of mesothelioma
- (2015) R. A. Stahel et al. ANNALS OF ONCOLOGY
- Global Cancer Incidence and Mortality Rates and Trends--An Update
- (2015) L. A. Torre et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Nicotine Reduces Survival via Augmentation of Paracrine HGF-MET Signaling in the Pancreatic Cancer Microenvironment
- (2015) D. Delitto et al. CLINICAL CANCER RESEARCH
- Update on Biomarkers of Hepatocellular Carcinoma
- (2015) Roongruedee Chaiteerakij et al. Clinical Gastroenterology and Hepatology
- Novel Roles of c-Met in the Survival of Renal Cancer Cells through the Regulation of HO-1 and PD-L1 Expression
- (2015) Murugabaskar Balan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High levels of c-Met is associated with poor prognosis in glioblastoma
- (2015) Stine Asferg Petterson et al. JOURNAL OF NEURO-ONCOLOGY
- miR-144-3p exerts anti-tumor effects in glioblastoma by targeting c-Met
- (2015) Fengming Lan et al. JOURNAL OF NEUROCHEMISTRY
- Whole genomes redefine the mutational landscape of pancreatic cancer
- (2015) Nicola Waddell et al. NATURE
- High c-Met expression is a negative prognostic marker for colorectal cancer: a meta-analysis
- (2015) HeLi Gao et al. TUMOR BIOLOGY
- Down-regulation of c-Met and Bcl2 by microRNA-206, activates apoptosis, and inhibits tumor cell proliferation, migration and colony formation
- (2015) Chengcao Sun et al. Oncotarget
- Non-small-cell lung cancer
- (2015) Cesare Gridelli et al. Nature Reviews Disease Primers
- Clinical significance of MET in gastric cancer
- (2015) Mikito Inokuchi World Journal of Gastrointestinal Oncology
- Childhood and adolescent cancer statistics, 2014
- (2014) Elizabeth Ward et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Significance of c-MET overexpression in cytotoxic anticancer drug-resistant small-cell lung cancer cells
- (2014) Hiroaki Ozasa et al. CANCER SCIENCE
- MET Is a Potential Target across All Papillary Renal Cell Carcinomas: Result from a Large Molecular Study of pRCC with CGH Array and Matching Gene Expression Array
- (2014) L. Albiges et al. CLINICAL CANCER RESEARCH
- Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling
- (2014) Katia Nones et al. INTERNATIONAL JOURNAL OF CANCER
- Improved Survival with Bevacizumab in Advanced Cervical Cancer
- (2014) Krishnansu S. Tewari et al. NEW ENGLAND JOURNAL OF MEDICINE
- DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification
- (2014) C V Camacho et al. ONCOGENE
- c-Met signaling in the development of tumorigenesis and chemoresistance: Potential applications in pancreatic cancer
- (2014) Daniel Delitto WORLD JOURNAL OF GASTROENTEROLOGY
- ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer
- (2014) Sandra Van Schaeybroeck et al. Cell Reports
- High MET expression is an adverse prognostic factor in patients with triple-negative breast cancer
- (2013) F Zagouri et al. BRITISH JOURNAL OF CANCER
- Targeting the Hepatocyte Growth Factor/c-Met Signaling Pathway in Renal Cell Carcinoma
- (2013) Lauren C. Harshman et al. CANCER JOURNAL
- α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells
- (2013) Hiromitsu Michikoshi et al. CANCER LETTERS
- The MET Oncogene in Glioblastoma Stem Cells: Implications as a Diagnostic Marker and a Therapeutic Target
- (2013) C. Boccaccio et al. CANCER RESEARCH
- Targeting the HGF/c-MET Pathway in Hepatocellular Carcinoma
- (2013) L. Goyal et al. CLINICAL CANCER RESEARCH
- Integration of New Genes into Cellular Networks, and Their Structural Maturation
- (2013) G. Abrusan GENETICS
- MET is a potential target for use in combination therapy with EGFR inhibition in triple-negative/basal-like breast cancer
- (2013) Yu Jin Kim et al. INTERNATIONAL JOURNAL OF CANCER
- Initial Clinical Sensitivity and Acquired Resistance to MET Inhibition in MET-Mutated Papillary Renal Cell Carcinoma
- (2013) Jennifer R. Diamond et al. JOURNAL OF CLINICAL ONCOLOGY
- SOCS3 Deletion in T Lymphocytes Suppresses Development of Chronic Ocular Inflammation via Upregulation of CTLA-4 and Expansion of Regulatory T Cells
- (2013) C.-R. Yu et al. JOURNAL OF IMMUNOLOGY
- The war on cancer: are we winning?
- (2013) M. J. Duffy TUMOR BIOLOGY
- Cabozantinib as a Novel Therapy for Renal Cell Carcinoma
- (2013) Ulka Vaishampayan Current Oncology Reports
- Hepatocyte Growth Factor Signaling in Intrapancreatic Ductal Cells Drives Pancreatic Morphogenesis
- (2013) Ryan M. Anderson et al. PLoS Genetics
- Targeted therapy: tailoring cancer treatment
- (2013) Min Yan et al. Chinese Journal of Cancer
- Knockdown of RON receptor kinase delays but does not prevent tumor progression while enhancing HGF/MET signaling in pancreatic cancer cell lines
- (2013) S Zhao et al. Oncogenesis
- Inhibition of c-Met activation sensitizes osteosarcoma cells to cisplatin via suppression of the PI3K–Akt signaling
- (2012) Kelai Wang et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Progress in cancer therapy targeting c-Met signaling pathway
- (2012) Kyung Hee Jung et al. ARCHIVES OF PHARMACAL RESEARCH
- Increased MET and HGF gene copy numbers are associated with trastuzumab failure in HER2-positive metastatic breast cancer
- (2012) G Minuti et al. BRITISH JOURNAL OF CANCER
- The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
- (2012) F. De Bacco et al. CANCER RESEARCH
- Met Kinase Inhibitor E7050 Reverses Three Different Mechanisms of Hepatocyte Growth Factor-Induced Tyrosine Kinase Inhibitor Resistance in EGFR Mutant Lung Cancer
- (2012) W. Wang et al. CLINICAL CANCER RESEARCH
- Enhancement of the Antiproliferative Activity of Gemcitabine by Modulation of c-Met Pathway in Pancreatic Cancer
- (2012) Amir Avan et al. CURRENT PHARMACEUTICAL DESIGN
- MiR-410 regulates MET to influence the proliferation and invasion of glioma
- (2012) Lingchao Chen et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinoma
- (2012) Shunsuke Kondo et al. International Journal of Clinical Oncology
- Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship
- (2012) Julian R. Molina et al. MAYO CLINIC PROCEEDINGS
- MET Activation Mediates Resistance to Lapatinib Inhibition of HER2-Amplified Gastric Cancer Cells
- (2012) C.-T. Chen et al. MOLECULAR CANCER THERAPEUTICS
- MicroRNA-34a Inhibits the Proliferation and Metastasis of Osteosarcoma Cells Both In Vitro and In Vivo
- (2012) Kang Yan et al. PLoS One
- Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1
- (2012) Lauren Averett Byers et al. Cancer Discovery
- Activating mutation in MET oncogene in familial colorectal cancer
- (2011) Deborah W Neklason et al. BMC CANCER
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- MET Expression and Amplification in Patients with Localized Gastric Cancer
- (2011) Y. Y. Janjigian et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Lung Cancer: Epidemiology, Etiology, and Prevention
- (2011) Charles S. Dela Cruz et al. CLINICS IN CHEST MEDICINE
- c-Met Is a Marker of Pancreatic Cancer Stem Cells and Therapeutic Target
- (2011) Chenwei Li et al. GASTROENTEROLOGY
- c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma
- (2011) Hanning You et al. HEPATOLOGY
- Hepatocyte growth factor twenty years on: Much more than a growth factor
- (2011) Takahiro Nakamura et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Small-cell lung cancer
- (2011) Jan P van Meerbeeck et al. LANCET
- A direct role for Met endocytosis in tumorigenesis
- (2011) Carine Joffre et al. NATURE CELL BIOLOGY
- Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme
- (2011) H J Jun et al. ONCOGENE
- Targeting c-Met as a promising strategy for the treatment of hepatocellular carcinoma
- (2011) Jianjun Gao et al. PHARMACOLOGICAL RESEARCH
- c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
- (2011) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of HGF/Met Signaling to Brk and Sam68 in Breast Cancer Progression
- (2011) Alessia Locatelli et al. Hormones & Cancer
- Does hepatocyte growth factor/c-Met signal play synergetic role in lung cancer?
- (2010) Xiangdong Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Marker Expression in Circulating Cancer Cells of Pancreatic Cancer Patients
- (2010) Jiahua Zhou et al. JOURNAL OF SURGICAL RESEARCH
- High MET Gene Copy Number Leads to Shorter Survival in Patients with Non-small Cell Lung Cancer
- (2010) Heounjeong Go et al. Journal of Thoracic Oncology
- MET signalling: principles and functions in development, organ regeneration and cancer
- (2010) Livio Trusolino et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Small Cell Lung Cancer: Past, Present, and Future
- (2010) Estelamari Rodriguez et al. Current Oncology Reports
- Osteosarcoma treatment: state of the art
- (2009) Hang T. Ta et al. CANCER AND METASTASIS REVIEWS
- MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes
- (2009) Y. Li et al. CANCER RESEARCH
- Epithelial-mesenchymal transition in cancer development and its clinical significance
- (2009) Masaaki Iwatsuki et al. CANCER SCIENCE
- Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells
- (2009) Koji Kawaguchi et al. CARCINOGENESIS
- Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
- (2009) Ji Luo et al. CELL
- Recent Advances in Cancer Therapy: An Overview
- (2009) A. Urruticoechea et al. CURRENT PHARMACEUTICAL DESIGN
- Targeting the Met signaling pathway in renal cancer
- (2009) Alessio Giubellino et al. Expert Review of Anticancer Therapy
- Src and FAK mediate cell-matrix adhesion-dependent activation of met during transformation of breast epithelial cells
- (2009) Angela Y. Hui et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- IncreasedMETGene Copy Number Negatively Affects Survival of Surgically Resected Non–Small-Cell Lung Cancer Patients
- (2009) Federico Cappuzzo et al. JOURNAL OF CLINICAL ONCOLOGY
- Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer
- (2009) M. G. Ponzo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prognostic significance of c-Met expression in glioblastomas
- (2008) Doo-Sik Kong et al. CANCER
- c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases
- (2008) Zhao-Shi Zeng et al. CANCER LETTERS
- miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells
- (2008) Na Li et al. CANCER LETTERS
- Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer
- (2008) Katsuhiro Okuda et al. CANCER SCIENCE
- METgene amplification orEGFRmutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors
- (2008) Takafumi Kubo et al. INTERNATIONAL JOURNAL OF CANCER
- MET as a target for treatment of chest tumors
- (2008) Nicole A. Cipriani et al. LUNG CANCER
- Malignant Gliomas in Adults
- (2008) Patrick Y. Wen et al. NEW ENGLAND JOURNAL OF MEDICINE
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